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      community KX-826 1% Phase II Results from China Just Dropped

      in Research/Science  37 upvotes 10 months ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community Epidemic of brand names working wildly different, if at all.

       6 upvotes 6 years ago
      The conversation discusses the variability in effectiveness of medications, including finasteride, and questions whether different manufacturers impact results. The user suggests sharing successful brands to help others identify effective options.

      community Happiness is just a gap between sheds

      in Progress Pictures  107 upvotes 7 months ago
      A user shared their experience with hair loss treatments, switching from 1mg finasteride and topical minoxidil to 5mg oral minoxidil and oral dutasteride, noting improvements despite shedding phases. Other users discussed the hair growth cycle, treatment effects, and shared advice on managing hair loss, including buzzing hair and maintaining mental health.

      community Lowering scalp prolactine - Any ideas ?

      in Treatment  2 upvotes 2 years ago
      The conversation is about finding the best method to lower scalp prolactine, with suggestions like P5P and Melatonin. The user also mentions HMI115 as a potential treatment and seeks feedback from those who have tried these methods.

      community New to this, new some opinions

      in General  49 upvotes 1 year ago
      The user has been using Minoxidil and finasteride for a year with good progress but is now experiencing increased hair shedding. They are concerned and questioning if this is normal or a cause for worry.

      community Bryan Johnson and his Hair routine, what's the point?

      in Hair Systems  24 upvotes 2 months ago
      Dutasteride and high-dose Minoxidil are the primary treatments maintaining hair, with additional supplements and therapies like red light offering minimal extra benefit. The discussion criticizes promoting expensive hair care products when basic medications are doing most of the work.

      community Anyone in the discord server for pp405 research?

      in Chat  5 upvotes 9 months ago
      The conversation is about users trying to regain access to a Discord server related to pp405 research, with differing opinions on the effectiveness of pp405 for hair loss. Specific treatments like Minoxidil, finasteride, and RU58841 are not mentioned in the conversation.

      community Shedding after 2 years what’s the reason?

      in Is this regrowth?  1 upvotes 1 year ago
      The user experienced increased hair shedding after switching to a new treatment with higher doses of finasteride (0.3%), minoxidil (7%), ketoconazole (2.2%), and biotin (0.2%). They are curious about the shedding but not concerned about noticeable thinning.

      community KX-826 Phase 3 Failed. Sorry guys...

      in Research/Science  48 upvotes 2 years ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community Breezula - what's the consensus?

      in Research/Science  7 upvotes 5 years ago
      People are discussing Breezula, a hair loss treatment, with mixed opinions on its value for the cost. Some are interested in it, while others think it's not worth the money.

      community Pyrilutamide/KX-826 for women?

      in Treatment  1 upvotes 1 year ago
      Pyrilutamide/KX-826 is being considered as a potential treatment for female androgenetic alopecia (AGA), but its high cost and limited data on effectiveness are concerns. Kintor markets it for both men and women.

      community Shampoo for a thicker appearance

      in Advice  23 upvotes 6 years ago
      A user recommends a biotin collagen shampoo for making hair appear thicker and feeling nice. Another user mentions using a similar product with argan oil from Walmart.

      community Any long term RU55841 / CB-03-01 / Eucapil users here?

      in Research/Science  9 upvotes 5 years ago
      Hair loss treatments RU55841, CB-03-01, and Eucapil were discussed, with concerns about needing increased dosages over time and potential side effects. A user suggested that CB's results could be due to various factors and that combining it with finasteride might slow down any upregulation.

      community Updates about KX-826 & GT20029

      in Research/Science  16 upvotes 3 years ago
      The conversation discusses potential advancements in two hair loss drugs, KX-826 and GT20029, and the interest in whether transitioning from oral finasteride to these drugs would maintain hair growth. One reply expresses skepticism about the compounds' representation.

      community DHT Gel (2.5%) to beard area + Dut + Pyri 1% + Minox

      in Research/Science  5 upvotes 8 months ago
      The conversation discusses using a combination of DHT gel, dutasteride, pyrilutamide, and minoxidil to promote beard growth while minimizing hair loss. Users suggest consulting a doctor and considering genetic factors before proceeding.

      community Duasteride and breast tissue accumulation.

      in Finasteride/Dutasteride  4 upvotes 4 months ago
      The user is experiencing breast tissue growth from taking dutasteride and minoxidil, and is considering reducing the dosage or stopping the medication. Suggestions include seeing an endocrinologist, using Raloxifene or Arimidex, and considering topical treatments or surgery if necessary.

      community My current nuclear stack. Thoughts?

      in Chat  7 upvotes 2 years ago
      The user is using RU58841 twice daily, dutasteride 0.5mg every two days, dutasteride mesotherapy every three months, and 20mg oral minoxidil daily. Other users suggest this regimen is excessive and recommend adding microneedling and ketoconazole shampoo.

      community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

       22 upvotes 8 years ago
      Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.

      community Hair thinning and gut health

       5 upvotes 8 years ago
      The conversation discusses hair thinning potentially linked to gut health issues and suggests biotin as a possible treatment. It also mentions that hair thinning could be due to male pattern baldness (MPB).

      community (UPDATE) 1y and 4m progress. 1mg fin daily, minoxidil foam twice a day, keto shampoo every other hair wash and hims thick fix shampoo and conditioner. Added saw palmetto, biotin + keratin and dermarolling into my routine. super happy, so glad hair loss isn’t consuming my life anymore

      in Progress Pictures  39 upvotes 2 years ago
      The individual has seen hair regrowth over a period of 1 year and 4 months using 1mg finasteride daily, minoxidil foam twice daily, ketoconazole shampoo, thick fix shampoo and conditioner, saw palmetto, biotin, keratin, and dermarolling. They are pleased with the results and no longer feel overwhelmed by hair loss.

      community 6 Months progress, and some second shed anxiety

      in Progress Pictures  10 upvotes 10 months ago
      The user shared progress pictures of their hair journey, noting good results after initial shedding but experiencing a second, more intense shed. They use topical Minoxidil twice daily, Tretinoin at night, oral finasteride daily, and ketoconazole shampoo weekly.

      community Second shed is real guys !!!!!

      in Is this regrowth?  134 upvotes 3 months ago
      The conversation discusses hair shedding experienced by users on minoxidil and finasteride treatments, with some considering additional options like spironolactone and dutasteride. Many users report experiencing a second shedding phase but are advised to continue treatment as it may lead to thicker hair regrowth.