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      community Treating my DUPA via controlling inflammation

      in Treatment  5 upvotes 2 years ago
      The user has DUPA and suspects autoimmune activity as a cause. They have tried various treatments including finasteride, minoxidil, dutasteride, pyrilutamide, estrogel, hydrocortisone, and clobetasol, and are now seeking a long-term immunosuppressant.

      community Are 10% fluridil formulations effective?

      in Treatment  6 upvotes 2 years ago
      The user is asking if using a 10% fluridil formulation would be effective for blocking scalp androgens in addition to their current treatment of oral dutasteride.

      community 5 months progress oral min and fin

      in Progress Pictures  377 upvotes 2 years ago
      A user shared 5 months of progress using 1mg finasteride and 2.5mg minoxidil, showing before and after pictures. Other users complimented the results and discussed their own experiences with similar treatments.

      community Topical dutasteride significantly outperforms oral finasteride

      in Research/Science  65 upvotes 9 months ago
      Topical dutasteride 0.05% is reported to outperform oral finasteride with minimal side effects, but concerns about study bias exist due to company funding. Some users report mixed results with topical dutasteride, noting issues with skin penetration and systemic absorption.

      community Ligand Chem cease trading Pyrilutamide

      in Product  14 upvotes 3 years ago
      Pyrilutamide, a possible hair loss treatment, ceasing to be traded due to patent laws; and the hope that this indicates it may be a legitimate treatment.

      community Why was fluridil abandoned and never made past phase 2?

      in Chat  4 upvotes 4 years ago
      Fluridil was abandoned due to its weak effectiveness and low binding affinity to the androgen receptor, making it less competitive against DHT and testosterone. Users discuss its limited results compared to other treatments like pyrilutamide and RU58841.

      community 5 months topical fin + min + tret hairline

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      A 20-year-old male has been using a topical mix of finasteride, minoxidil, and tretinoin for five months without seeing significant hairline improvement. He is considering adding oral dutasteride or a hair transplant for better results.

      community 5 months only topical minoxidil

      in Progress Pictures  155 upvotes 1 month ago
      Minoxidil is effective for hair growth but may not provide lasting results without addressing DHT, which finasteride or dutasteride can help with. Users report mixed experiences with side effects from these treatments, including acne and itching from minoxidil.

      community 5 months Minoxidil+Fin progress

      in Is this regrowth?  74 upvotes 6 months ago
      The conversation is about a user's 5-month progress using topical Minoxidil (5%) and Finasteride (0.1%) twice daily, along with derma stamping, improved Vitamin D levels, and increased protein intake for hair regrowth. The user is considering dutasteride if progress plateaus and uses a sulfate and paraben-free shampoo.

      community 5 months 1mg Fin 4 month 5% Min

      in Progress Pictures  573 upvotes 1 year ago
      A 27-year-old user shared their 5-month progress using 1mg finasteride daily and 5% minoxidil twice a day for hair loss, reporting improved hair growth despite initial shedding and experiencing only minor side effects like watery semen. They also use Nizoral shampoo, take a multivitamin, and plan to start microneedling if progress slows.

      community High DHT with finasteride. Help!

      in Finasteride/Dutasteride  6 upvotes 2 years ago
      Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.

      community Using liquid cetirizine as a topical?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses using liquid cetirizine as a topical treatment for hair loss. It mentions Minoxidil, finasteride, and RU58841 as other treatments.

      community Hydrophobic Finasteride. Why don’t we have it?

      in Chat  6 upvotes 1 year ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.

      community Clascoterone phase 3 results are out!

      in Treatment  83 upvotes 6 months ago
      Clascoterone phase 3 results show promising improvements in hair count, but concerns about high costs and lack of detailed data remain. Users compare it to existing treatments like Minoxidil and Finasteride, expressing skepticism about its accessibility and effectiveness.

      community Crazy idea: creatine + topical finasteride

      in Chat  22 upvotes 4 years ago
      Using topical finasteride with creatine might help reduce hair loss by targeting local DHT while maintaining normal systemic levels, but results are uncertain without testing. Users report mixed experiences with topical treatments like finasteride, dutasteride, RU58841, and minoxidil, with some seeing regrowth and others experiencing side effects.

      community B5 (Pantothenic acid), B7 (Biotin), B12

      in Treatment  4 upvotes 2 years ago
      The conversation discusses the effects of B5 (Pantothenic acid), B7 (Biotin), and B12 on hair loss. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.