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      community Alfatradiol only for mild thinning

      in Product  1 upvotes 9 months ago
      Alfatradiol is considered safe but less effective than finasteride for hair loss. One user reported subtle regrowth using alfatradiol with finasteride and minoxidil, while another found alfatradiol ineffective.

      community Question about solution to pill conversion

      in General  67 upvotes 1 year ago
      The user left their 2.5 mg pills at home and is considering using 5% topical minoxidil as a substitute. They also inquire about where to obtain over-the-counter minoxidil pills.

      community The urge to buy Clascoterone 5% solution

      in Research/Science  11 upvotes 7 months ago
      Clascoterone 5% solution is not yet commercially available, with only the 1% solution currently sold for acne. Users discuss the potential of Clascoterone as a hair loss treatment, comparing it to other anti-androgens like RU58841 and Eucapil.

      community Pyrilutamide bulk powder purchasing

      in Product  2 upvotes 1 year ago
      Pyrilutamide is being used effectively for hair loss with no side effects, and the user is seeking a cheaper bulk supplier. Users discuss the difficulty of finding affordable, trustworthy sources, with some suggesting potential suppliers.

      community Thoughts on Lactobacillus Reuteri 6475?

      in Treatment  3 upvotes 1 year ago
      Lactobacillus reuteri 6475 is being used by a person who reports healthier hair after one month, despite initial shedding. The discussion includes speculation about its effects on gut bacteria and scalp inflammation.

      community Formula 82f and Keto?

      in Minoxidil  70 upvotes 1 year ago
      A user is using a topical treatment called Formula 82f, which contains finasteride, minoxidil, and a steroid, along with Ketoconazole shampoo for hair loss. They are considering whether to switch to oral medication for better results.

      community Histamine intolerance and topical treatments

      in Treatments  66 upvotes 1 year ago
      The user experiences histamine intolerance with alcohol-based hair loss treatments like Rogaine foam and seeks alternatives. Suggestions include alcohol-free and PPG-free topical minoxidil or finasteride, and trying Spectral products with different solvents.

      community Warning: Your Rogaine Foam Might Not Contain Minoxidil

      in Minoxidil  373 upvotes 2 years ago
      A user experienced significant hair loss after using Rogaine foam purchased from Amazon, which failed a bleach test for Minoxidil. They discovered that even legitimate Rogaine products might be faulty and advised buying from reputable sources.

      community Flakey scalp due to minoxidil?

      in Minoxidil  7 upvotes 1 year ago
      Minoxidil can cause scalp flaking and dryness, often due to its alcohol content. Switching to foam minoxidil or using antifungal shampoos like Ketoconazole may help reduce these side effects.

      community Creatine is the opposite of minoxidil !

      in Research/Science  315 upvotes 9 months ago
      Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

      community Best solution for pyrilutamide in UK?

      in Treatment 2 years ago
      The user is looking for a PG-free solvent in the UK or EU to make their own pyrilutamide solution for hair loss and is currently using finasteride, considering minoxidil. They hope pyrilutamide will help stabilize their hair loss.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 3 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community Handle the itch from Minoxidil?

      in Minoxidil  1 upvotes 4 months ago
      Minoxidil can cause scalp itchiness, often due to propylene glycol, and users suggest alternatives like foam formulations without PG, using moisturizing oils, or reducing application frequency. Some recommend ketoconazole or zinc pyrithione shampoos to help with inflammation and itchiness.

      community Chinese source for pyrilutamide or ru8841 ?

      in Product  3 upvotes 9 months ago
      The conversation is about finding a reliable Chinese source for pyrilutamide or RU58841, ideally with a third-party Certificate of Analysis from Janoshik Analytical. The user is seeking recommendations for these hair loss treatments.

      community Koshine826 PRO 1% is available

      in Chat  35 upvotes 1 year ago
      The conversation is about the availability of Koshine826 PRO 1% for hair loss treatment. The discussion includes Minoxidil, finasteride, and RU58841.

      community Azelaic acid with ru58841 combination

      in Treatment 5 months ago
      The conversation discusses using azelaic acid to reduce scalp inflammation while using RU58841 for hair loss. It suggests applying azelaic acid in the morning and RU58841 at night to avoid degradation, while also using dutasteride and minoxidil.

      community Leaving Ketoconazole Shampoo on for Longer

      in Ketoconazole  15 upvotes 2 years ago
      The conversation is about using Ketoconazole shampoo for hair loss, with users discussing leaving it on the scalp for longer periods. Some users report benefits for dandruff, but there's uncertainty about its effectiveness for androgenetic alopecia (AGA).