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community Can we get a reality check on PP405?

in Research/Science 83 upvotes 6 months ago

PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

community 4 years on fin and min (Before and After) Age 27 to 31

in Progress Pictures 997 upvotes 6 months ago

A user experienced significant hair regrowth using finasteride and minoxidil over four years, despite side effects like seborrheic dermatitis, urinary changes, and water retention. They were satisfied with the results and maintained a strong physique.

community P-1075: a BETTER version of Minoxidil

in Research/Science 6 months ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

community The Health Benefits of Head Hair

in Research/Science 19 upvotes 6 months ago

Hair provides protection against head trauma, reduces skin cancer risk, helps remove heavy metals, and aids in wound healing. The conversation emphasizes the health benefits of maintaining head hair beyond cosmetic reasons.

community 17 y/o Male Considering Finasteride + Minoxidil for Early Balding - Seeking Advice

in Finasteride 136 upvotes 6 months ago

A 17-year-old male is experiencing genetic hair thinning and is considering using finasteride and minoxidil for treatment. He is frustrated with dermatologists' suggestions of vitamins and seeks advice on effective solutions.

community Serum based on plant extracts boosts hair growth in weeks.

in Treatment 44 upvotes 6 months ago

A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

in Research/Science 65 upvotes 6 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community 19M with Diffuse and Crown Thinning: Start Minoxidil or Seek Second Opinion?

in General 158 upvotes 6 months ago

A 19-year-old male with diffuse and crown thinning is considering starting minoxidil as advised by a dermatologist but is unsure if he should seek a second opinion. Another user suggests consulting a reputable dermatologist to avoid wasting resources.

community Pelage, PP405, is creating a database for potential new trial volunteers

in Research/Science 149 upvotes 6 months ago

PP405 is a new hair loss treatment targeting dormant hair follicles, with ongoing trials. Some users consider stopping finasteride and minoxidil to join trials, while others doubt its effectiveness.

community How to cope with starting fin/dut too late

in Chat 9 upvotes 6 months ago

Regret over not starting hair loss treatments like finasteride and minoxidil earlier, leading to significant hair loss. Users discuss coping strategies, including buzzing hair, staying on medications, and considering future treatments.

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