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      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community Pp405 full presentation on new topical

      in Product  105 upvotes 2 months ago
      A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.

      community RU58841 is the only thing that worked for me, a DUPA sufferer

      in Treatment  1 upvotes 11 months ago
      RU58841 was the only treatment that slowed hair loss and reduced irritation for a DUPA sufferer after trying finasteride, minoxidil, and dutasteride with no success. The user continues using 6mg oral minoxidil, 0.5mg dutasteride, and an 8% RU58841 solution.

      community 108 days of dutasteride 0,5 mg daily use 25M

      in Progress Pictures  832 upvotes 1 year ago
      A user experienced positive hair regrowth after 108 days of using 0.5 mg daily Dutasteride and Alpecin caffeine shampoo, without Minoxidil. The discussion included advice on dosage, potential side effects, and comparisons with Finasteride and Minoxidil.

      community Pyrilutamide Trial Phase 3 Results?

      in Research/Science  10 upvotes 2 years ago
      The conversation is about the release of Phase 3 trial results for pyrilutamide in China for treating hair loss. The user is inquiring if the actual results have been posted, noting that a recent release did not contain them.

      community Pyrilutamide 3 weeks update once a day

      in Progress Pictures  33 upvotes 3 years ago
      User shared 3-week progress using Pyrilutamide once a day for hair loss. Another user shared their 3-month progress with 0.25% concentration Pyrilutamide, experiencing rollback of 4 years in 3 months.

      community Spironolactone or bicalutamide prescription

      in Treatment  4 upvotes 2 years ago
      The conversation is about someone seeking a doctor in the EU who prescribes spironolactone or bicalutamide for female pattern hair loss, as they are having difficulty finding treatment options beyond Minoxidil in Austria. They are asking for recommendations and are open to direct messages for assistance.

      community What’s the deal with pyrilutamide?

      in Research/Science  53 upvotes 4 years ago
      The effectiveness of pyrilutamide, a hair loss treatment, with research results being postponed until September. Various people shared their experiences with topical finasteride, minoxidil and RU58841, as well as other treatments such as dandruff shampoo, group buys and grey markets.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  122 upvotes 8 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community My Pyrilutamide Experience Update 2 Part 2 PICS

      in Progress Pictures  54 upvotes 3 years ago
      The user's experience with Pyrilutamide for hair loss treatment, including their belief that it has sparked improvements in combination with other treatments such as Minoxidil and Finasteride. Another user was also hoping to see results from using Pyrilutamide alone.

      community Is it possible/legal to buy clascoterone in Spain?

      in Treatment  2 upvotes 10 months ago
      The user has tried various hair loss treatments, including topilutamide, alfatradiol, pyrilutamide, and topical spironolactone, but experienced headaches. They are inquiring about the availability and legality of clascoterone in Spain.

      community Almost 3 months on pyrilutamide

      in Treatment  32 upvotes 3 years ago
      A user's experience with Pyrilutamide, which they have been taking for 3 months to treat their aggressive male pattern baldness. The user reported that the medication decreased shedding and was hopeful it would work as advertised.

      community Pyrilutamide update number 1 - 1 week use

      in Update  55 upvotes 3 years ago
      A user who is using Pyrilutamide, Finasteride, and a homemade topical solution to treat their hair loss. Replies mentioned the potential of Pyrilutamide being a "cure" for hair loss and a reminder that results may not be credited solely to it.

      community Alright so FDA better approve PP405 as fast as they approved covid vaccine

      in Product  128 upvotes 10 months ago
      PP405 is a potential hair loss treatment showing promising early results, with hopes for market release by 2028, but skepticism remains due to inconclusive data and past disappointments with similar products. Current treatments like Minoxidil and Finasteride have side effects, leading some to anticipate PP405 as a safer alternative, though its effectiveness compared to placebo is debated.

      community Anyone used Pyril? Any updates from existing users?

      in Research/Science  17 upvotes 3 years ago
      Researching the effectiveness of the hair loss treatment Pyril in comparison to other treatments such as Minoxidil, Finasteride, and RU58841. Replies suggest that users often fail to provide updates on their experience with Pyril.

      community GT20029 - Promising phase II results

      in Research/Science  15 upvotes 2 years ago
      GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

      community Pyrilutamide at 16 years old- update 2

      in Research/Science  21 upvotes 3 years ago
      A 16-year-old researching and trying Pyrilutamide for hair loss treatment, reporting back on side effects experienced after one week of use; the reported side effects included testicle pain, headache, and increased shedding. Libido and sexual performance seemed unaffected.

      community 4 Month Update on Pyrilutamide

      in Update  11 upvotes 3 years ago
      Hair loss treatment with Pyrilutamide, Minoxidil, and Finasteride showed improvement after 4 months. Shedding reduced, hair feels stronger and healthier, with no side effects.