PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.
The conclusion of the conversation is that the user, PirateBeastBaby, had good results with microneedling for hair loss after using oral finasteride and topical minoxidil 20 years ago. They believe that microneedling was the gamechanger for their hair growth.
A 25-year-old male using Dutasteride, oral Minoxidil, and Ketoconazole shampoo is experiencing increased hair shedding and vellus hair growth along the hairline. Concerns are raised about whether this is a seasonal shed or a potential setback.
The user "dsx460" shared their progress pictures of hair regrowth using a combination of topical finasteride, minoxidil, microneedling, and a keto diet. They are happy with the progress and hope for further improvement.
The conversation discusses concerns about the potential risk of cancer from creating new hair follicles through microneedling, due to stem cell division. Specific treatments mentioned include microneedling, caffeine-containing anti-hair loss shampoos, and other unspecified topicals.
The conversation discusses the delay in bringing FAK inhibitors and Stanford's hydrogel to market for hair transplants, with a preference for FAK inhibitors over Verteporfin due to their superior potential in preventing scarring. The user expresses frustration over the slow progress and hopes for faster development by companies like FAKnostics.
A 40+ year old is regrowing their hairline using microneedling, minoxidil, tretinoin, low-level laser therapy, massages, and Nizoral, without using finasteride or dutasteride. They noted progress in hair growth below a birthmark, an area that hadn't seen growth since their teenage years.
The user is using ketoconazole shampoo, 5% minoxidil, and microneedling for hair loss treatment. It's suggested that adding a DHT suppressant like finasteride could improve results.
The user reports using topical minoxidil 6% and finasteride 0.05% once daily, along with microneedling, vitamins, biotin, and nizoral shampoo. They recently increased minoxidil and finasteride to twice daily and feel their hair is thicker but are unsure about regrowth.
The conversation discusses a 5-month hair loss treatment regimen including finasteride, minoxidil, RU58841, dermapen (1.7mm), and ketoconazole shampoo, with noticeable hair regrowth. One user notes the hair appears thicker, while another mentions RU58841 is not doctor-recommended.
OP is unsure if their hair is improving or worsening despite using Topical Fin, Pyri, Keto Shampoo, TGel, Microneedling, and Tretinoin. A user suggests switching to oral Fin and Minoxidil.
Ketoconazole shampoo may help with early-stage hair loss by stopping hair regression and promoting new hair growth, though its effectiveness as a DHT blocker is debated. Users report varying results, with some experiencing dryness and others seeing improvement when used 2-3 times a week.
The user experienced significant hair density improvement over seven months using finasteride, topical minoxidil, Nizoral shampoo, and supplements like biotin and vitamin D. They also used a derma stamp with rosemary and peppermint oil, noting no side effects from finasteride.
A female user's six-month progress with only minoxidil and ketoconazole, including their experiences before and after using the treatments. They also discussed the differences between male and female hair loss and suggested that meds may offer more progress, though some results can be had without them.
User discusses verteporfin for hair regrowth through "super microneedling" and preventing scarring. They mention a case of an old man regrowing hair after a head injury and suggest verteporfin could recreate this result.
The user is experiencing thicker hair after using oral minoxidil, dutasteride, biotin, collagen shampoo with rosemary, and ketoconazole. They are considering adding a derma roller to their regimen for potential benefits.
The user has been using topical finasteride and minoxidil for two years with decent regrowth and recently added microneedling to their routine. They are questioning if the small hairs observed are new regrowth from microneedling or just vellus or miniaturized hairs.
OP shared 9-month hair regrowth progress using 1mg finasteride, 5% minoxidil, 2% ketoconazole, and a dermapen. Users discussed side effects, application methods, and additional treatment suggestions.
The user is experiencing positive results in hair regrowth using a protocol that includes minoxidil, dutasteride, essential growth serum, argan oil, trioxidil shampoo, ketoconazole shampoo, and microneedling. They express hope and satisfaction with the progress after six weeks of treatment.
Adipose-derived stem cells with ATP improved hair regrowth in male and female mice with androgenetic alopecia. The most effective treatments were low dose stem cells with ATP for males and medium dose stem cells with non-liposomal ATP for females.
The user has been using topical minoxidil 8% and finasteride 0.3% for six months, along with 2% ketoconazole shampoo and microneedling. They are experiencing some hair regrowth and hope for thicker hair by next year.
Cold shock therapy may promote hair growth by stimulating follicular muscles and affecting stem cells. The exact mechanisms and full range of elements involved are not yet fully understood.
Microneedling and tretinoin may enhance minoxidil absorption for hair loss, but evidence on their effectiveness is limited. Iron supplements and broccoli sprouts are suggested for enzyme activation, but their impact on hair is unclear.
Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.
A 27-year-old male experienced hair loss and dermatitis, which improved with tea tree oil and neem extract. He is considering using a 2% Ketoconazole solution for further treatment.