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    GlossaryAmino Acid Metabolism

    processes by which the body breaks down and uses amino acids

    Amino acid metabolism refers to the processes by which the body breaks down and utilizes amino acids, the building blocks of proteins. This includes both catabolism (breaking down amino acids for energy or converting them into other compounds) and anabolism (using amino acids to build new proteins and other important molecules). These processes are crucial for maintaining muscle tissue, producing enzymes and hormones, and supporting overall cellular function.

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      community Fats on your Head to Stop Hair Loss?

      in Research/Science  141 upvotes 2 years ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community Dutasteride broked my liver (maybe)

      in Finasteride/Dutasteride  8 upvotes 3 years ago
      A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 6 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  98 upvotes 2 years ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 2 years ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community I cry every day, everything is very depressing

      in Finasteride/Dutasteride  52 upvotes 1 year ago
      A user is experiencing hair loss despite using dutasteride and oral minoxidil, feeling hopeless and considering a hair system. They are advised to try ketoconazole, seek a second opinion from a dermatologist, and consider treatments like finasteride, RU58841, and hair transplants.

      community DIY NutraKos-style 6–amino-acid mix (recipe + references)

      in Product  1 upvotes 3 months ago
      A user shared a DIY recipe for a NutraKos-style amino acid mix as a cost-effective alternative to the expensive product, suggesting it as a complementary supplement for hair loss. Another user argued that proven treatments like finasteride and minoxidil are more reliable, questioning the efficacy of the amino acid mix.

      community Thoughts on Revitacare Haircare Mesotherapy?

      in Product  2 upvotes 2 years ago
      A 17-year-old with AGA is considering Revitacare Haircare Mesotherapy, which includes hyaluronic acid, amino acids, zinc, and B vitamins, injected into the scalp. One reply dismisses it as ineffective.

      community oral hyaluronic acid supplements?

      in Treatment  5 upvotes 4 years ago
      Oral hyaluronic acid is not beneficial for hair, as it gets broken down in the stomach and has no strong evidence supporting its effectiveness. The user is taking finasteride, dutasteride, and topical minoxidil for hair loss, but combining finasteride and dutasteride is considered redundant.

      community Micronutrient testing, deficiencies, etc.

      in Treatment  4 upvotes 3 years ago
      Micronutrient testing and deficiencies related to hair loss, particularly androgenetic alopecia (AGA). Discussion includes the impact of iron, selenium, zinc, copper, folate, B12, vitamin E, vitamin D, amino acids, and fatty acids, alongside treatments like dutasteride or finasteride.

      community Progressi in 9 mesi, da luglio 2025 a marzo 2026

      in Progress Pictures  153 upvotes 1 month ago
      The user shared their 9-month hair regrowth progress using topical Minoxidil 5%, finasteride 0.05%, retinoic acid 0.01%, dermastamping, ketoconazole shampoo, and supplements like biotin. They experienced some hair density improvement but minimal change in the hairline, with initial side effects from finasteride that resolved after dosage adjustment.

      community Taurine supplements work for hair growth?

      in Product  8 upvotes 2 years ago
      The conversation discusses taurine supplements for hair growth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.

      community Small study on zinc and arginine

      in Research/Science  17 upvotes 5 years ago
      The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It also touches on a study involving zinc and L-arginine.

      community Stacking on top of Min/ Fin - adding hair supplements?

      in Product  1 upvotes 1 year ago
      The conversation is about adding Swisse Hair Nutrition for Men, which contains saw palmetto and various vitamins, to a Minoxidil and finasteride regimen to potentially enhance hair growth. The user is seeking feedback on the effectiveness of stacking these supplements with their current treatment.

      community Vegan Protein Powder Make Loss Worse?

      in Female  2 upvotes 1 year ago
      A user is experiencing genetic hair loss and is using spironolactone and minoxidil without success. They are considering switching to vegan protein powder due to digestive issues and are concerned if it will worsen hair loss.

      community (21M) 13 months into meds, hair fall's returning

      in Update  3 upvotes 1 year ago
      A 21-year-old male, 13 months into hair loss treatment, reports increased hair fall despite using Dutasteride, oral Minoxidil, vitamins, and specialized shampoos. He questions the impact of anxiety and depression on hair fall and is hesitant to seek therapy.

      community (20M) Minoxidil Tablets causing hairfall again

      in Minoxidil  2 upvotes 2 years ago
      A user experienced increased hair fall after starting Minoxidil tablets, despite following a comprehensive treatment plan for Seborrhoeic Capitis and Androgenetic Alopecia. They are unsure if the Minoxidil tablets are the cause and seek advice.

      community Natural Remedies: Polyphenols and Hair Loss

       18 upvotes 6 years ago
      Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

      community Sucess story for you guys, pics are 10+ years apart.

      in Progress Pictures  311 upvotes 2 years ago
      A user shared a success story showing hair regrowth over 10 years, attributing it to quitting creatine and taking 0.5mg finasteride. Some commenters were skeptical about creatine's impact, while others inquired about side effects, and the original poster reported no negative effects from finasteride.