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      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  739 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Has anyone tried this product or similar ?

      in Product  9 upvotes 9 months ago
      Minoxidil can be harmful to pets, especially cats. Users report mixed results with hair loss stabilization but no regrowth, and suggest buying Minoxidil, finasteride, and RU58841 separately to save money.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  215 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community Quitting minoxidil after 1.2 years of hair transplant

      in Transplants 7 months ago
      The user experienced side effects like dull skin and eye bags from minoxidil after a hair transplant and is considering alternatives like redensyl. They stopped using finasteride due to side effects and are concerned about maintaining hair without minoxidil.

      community Any treatment not nuking systemic DHT levels?

      in Finasteride/Dutasteride  16 upvotes 3 months ago
      Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.

      community topical minoxidil (5%) & kx826 (.5%) update.

      in Progress Pictures 9 months ago
      The user has been using topical minoxidil (5%) for two years and kx826/pyrilutamide for one year, after experiencing side effects from finasteride. They report positive results from the combination of minoxidil and kx826 in combating hair loss.

      community A concern regarding the upcoming androgen degrader drug GT20029

      in Chat  11 upvotes 1 year ago
      GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

      community Growth Stimulants that aren't Minoxidil...?

      in Research/Science  7 upvotes 2 years ago
      The user is exploring hair growth stimulants other than Minoxidil, mentioning Stemoxydine, various peptides, drugs like Latanoprost and Bimatoprost, and natural remedies such as Rosemary Oil and Caffeine. They express concerns about the long-term effectiveness and safety of these alternatives and seek more information on viable options for hair regrowth.

      community Microneedling to maintain results from min

      in Microneedling  7 upvotes 1 year ago
      Microneedling alone is not effective in maintaining minoxidil results for hair growth. Combining microneedling with minoxidil and finasteride may enhance results, but microneedling by itself is not a reliable treatment.

      community Oral Minoxidil only users (no fin-dut)

      in Minoxidil  4 upvotes 2 months ago
      Oral Minoxidil users discuss their experiences with hair regrowth, noting that results may be temporary without a DHT blocker. Some users report significant regrowth after several months but express concerns about needing additional treatments.

      community About GT20029's Efficacy and Strength

      in Chat  7 upvotes 3 years ago
      The conversation is about the effectiveness and production of GT20029, a drug being developed as a topical androgen receptor degrader for hair loss, and whether it can fully degrade androgen receptors or only partially. It also discusses the drug's potential unique working mechanism and synthesis by a company called Anagen.

      community Malassezia safe topical treatments?

      in Question  2 upvotes 7 years ago
      The user is seeking Malassezia-safe treatments for hair loss and currently uses a baby shampoo, a scalp tonic with antifungal ingredients, and aloe gel. They consider using Kirkland Minoxidil 5% drops and possibly consulting a doctor about Finasteride.

      community My doc asked me to use this, I'm 17

      in Finasteride/Dutasteride  11 upvotes 2 years ago
      A 17-year-old experiencing hair loss due to hard water was advised by a dermatologist to use a treatment containing Minoxidil and vitamins. A respondent confirmed the treatment's safety but warned that discontinuing Minoxidil could worsen hair loss.

      community Bicalutamide and muscles growth

      in Female  8 upvotes 1 year ago
      A 30-year-old woman with androgenetic alopecia is considering bicalutamide to slow hair loss but is concerned about its impact on muscle growth due to its anti-androgen effects. Alternatives suggested include dutasteride, spironolactone, RU58841, and minoxidil, with concerns about bicalutamide's side effects.

      community 1.5 years dut oral min results

      in Finasteride/Dutasteride  511 upvotes 2 years ago
      The conversation discusses a user's 1.5-year experience with oral minoxidil and dutasteride for hair loss, mentioning side effects like itchy nipples and ball ache. Specific treatments used are 5mg of minoxidil and 0.5mg of dutasteride daily.

      community Minoxidil permanent face changes?

      in Minoxidil  4 upvotes 4 years ago
      Excessive use of topical minoxidil led to unwanted facial changes and side effects. The user plans to switch to oral minoxidil with microneedling for hair regrowth.

      community Progress - 9 months oral minoxidil 2.5 mg & 4 months oral finasteride 1 mg

      in Progress Pictures  8 upvotes 8 months ago
      The user has been using oral minoxidil 2.5 mg for 9 months and oral finasteride 1 mg for 4 months, along with microneedling, and has noticed more baby hairs and longer eyelashes but no extra overall thickness. They are considering increasing the minoxidil dose but are concerned about safety due to potential side effects.

      community Is microneedling worth it when you're on dut and oral min?

      in Microneedling  11 upvotes 3 months ago
      Microneedling may not significantly enhance hair growth when combined with dutasteride and oral minoxidil, as its primary benefit is improving topical absorption. Some users suggest using a 1.5mm depth for potential follicle stimulation, but results and effectiveness vary.