Procapil is marketed as a natural hairloss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.
Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hairloss by blocking DHT and promoting hair growth.
A user added sandalore to minoxidil for hairloss, observing some vellus hair growth and less scalp inflammation. Others tried sandalore with mixed results, discussing dosage and effectiveness compared to minoxidil and finasteride.
Finasteride and dutasteride must be taken continuously to prevent hairloss, and minoxidil should also be used long-term. Patience is needed as results from these treatments can take months to over a year to appear.
A 24-year-old person who is worried about their hairloss after 14 months of taking finasteride and 11 months of minoxidil. Replies to the post suggested sticking with their current regimen, that shedding from one part may not be telogen effluvium, and that shedding is normal with these drugs and they should evaluate in two to three months.
PP405 is being discussed as a potential hairloss treatment, possibly more effective than minoxidil. There are concerns about its effectiveness and product contamination, but some users report early signs of hair regrowth.
Low-dose oral minoxidil is a safe and effective hairloss treatment with fewer side effects than previously feared. Users often prefer it over topical minoxidil for better results, though some experience side effects like increased body hair and cardiovascular issues.
UCLA's PP405 shows promise in reactivating dormant hair follicles for hairloss treatment but is still in clinical trials. Minoxidil and finasteride remain common treatments until PP405 becomes available.
The user has been using a strong combination of hairloss treatments for 16 months, including Finasteride, Minoxidil, Dutasteride, and RU-58841, but their hairloss has worsened. They're questioning whether their high testosterone levels or residual scalp DHT are causing further hairloss, with a reply suggesting that even small amounts of DHT can cause hairloss if one is sensitive to it.
IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hairloss.
A 28-year-old male experiencing hair thinning is considering minoxidil and finasteride. Minoxidil helps regrow hair, while finasteride prevents further loss; both are usually lifelong treatments.
The user experienced improved hair at 6 months using 0.5 mg finasteride daily but noticed more scalp visibility and potential hairloss at 13 months, questioning if this was due to shedding or the treatment not working. Some respondents suggested the possibility of a shed or scalp inflammation, while others observed improvements or advised checking for underlying scalp conditions.
The conversation is about creating a higher concentration of the newly FDA-approved hairloss treatment, Clascoterone (Winlevi), through compounding pharmacies and possibly organizing group purchases. Some users are unfamiliar with Winlevi and are asking for an explanation of the drug.
The post discusses a user's six-year progress with finasteride and a Follicular Unit Transplant (FUT) for hairloss. The user shared before and after photos in reverse order, leading to confusion, but overall, the community responded positively to the user's hair regrowth.
Federal funding cuts have delayed PP405 research, affecting hairloss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.
OP is considering adding dutasteride to their regimen of finasteride and minoxidil to address hairloss plateauing. Users suggest oral minoxidil, microneedling, and possibly a hair transplant, with mixed opinions on dutasteride's effectiveness for temple regrowth.
The conversation discusses a claim that avoiding coffee can lead to significant hair regrowth in individuals with androgenetic alopecia. Participants are skeptical, with some sharing personal anecdotes that contradict the claim, and others discussing the potential role of caffeine in hairloss and the effectiveness of other treatments like finasteride and minoxidil.
A user has been on dutasteride for nearly 2 years with no improvement in hairloss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.
Rejuv-3X, a topical blend with GHK-Cu, AHK-Cu, and JXL-089, is used for hairloss, offering a targeted option without finasteride's side effects. The user plans to combine it with microneedling for enhanced results.
The conversation discusses androgenic alopecia (AGA) and its treatments, focusing on finasteride, minoxidil, and ketoconazole shampoo. Finasteride is recommended as essential for preventing further hairloss.
Dutasteride reduces DHT more effectively than finasteride, but finasteride is more commonly used and approved for hairloss. Users have mixed opinions on dutasteride's effectiveness, with some experiencing better results and others facing side effects or no improvement.
Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hairloss management.
A user who is trying alternative treatments, such as mucuna pruriens dissolved in water/alcohol and a blend of jojoba oil, rosemary oil, and peppermint oil, for hairloss. Other users have shared anecdotal evidence, discussed the potential effectiveness of certain treatments, and questioned the time sensitivity of experimenting with new treatments.
A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hairloss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.
PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.
Mango oil may inhibit DKK1 and DHT, potentially aiding hair growth by activating the Wnt signaling pathway. A user plans to test mango leaves juice and other Ayurvedic products for hair regrowth.
PP405 is considered as a potential hair regrowth treatment, but users are skeptical due to past product failures. They compare it to Minoxidil and Finasteride, questioning its effectiveness and the intentions of pharmaceutical companies.
Switching to Dutasteride worsened hair condition, causing shedding and inflammation. The user will continue Dutasteride until 18 months before possibly switching back to Finasteride, while using oral Minoxidil.
After 11 years on Finasteride, a user's hair is thinning again, suggesting hair may become more sensitive to DHT with age. They plan to introduce Dutasteride once a week, as they cannot tolerate Minoxidil.