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      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  60 upvotes 1 month ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community Any treatment not nuking systemic DHT levels?

      in Finasteride/Dutasteride  17 upvotes 2 months ago
      Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.

      community Meds ain't working.its been a year on meds.23M

      in Update 2 months ago
      A 23-year-old male has been using finasteride, oral minoxidil, and dutasteride for a year to combat hair loss but sees no improvement and continues to lose over 100 hairs daily. Despite trying various treatments and consulting dermatologists, he feels hopeless and considers stopping the medications.

      community Turkey? Fin? Min? Fin+Min? Biotin? Keto? Saw? Dut? Nut?

      in Satire  1349 upvotes 5 months ago
      Hair loss treatments and celebrity hair maintenance, mentioning finasteride, minoxidil, RU58841, biotin, ketoconazole, saw palmetto, dutasteride, and Nutrafol. The tone is satirical, speculating on celebrities' use of hairpieces and transplants.

      community Average r/bald user complaining

      in Satire  398 upvotes 5 months ago
      Hair loss treatments like Minoxidil, finasteride, and RU58841, focusing on their effectiveness and side effects. It also highlights the disparity in medical research funding between hair loss and conditions like endometriosis.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  122 upvotes 6 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community Serum based on plant extracts boosts hair growth in weeks.

      in Treatment  42 upvotes 7 months ago
      A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.

      community risks with finasteride and dutasteride

      in Research/Science  138 upvotes 10 months ago
      Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

      community RU58841 in germany eventually facing legal charges

      in Hair Systems  32 upvotes 10 months ago
      The conversation discusses the use of RU58841 for hair loss, with concerns about its legality in Germany and potential legal consequences. Alternatives like finasteride and dutasteride are mentioned, with some users questioning the effectiveness and safety of RU58841.

      community What is the cause of "DHT itch"?

      in Research/Science  7 upvotes 1 year ago
      The conversation discusses the effects of using Tongkat ali and dioscorea to raise DHT levels, leading to increased body hair growth and an itchy scalp, without causing hair loss. The discussion also debates the role of DHT in male characteristics and its impact on sexual function, with differing opinions on its importance and effects.

      community Ru58841 + topical minoxidil + microneedling succes story

      in Progress Pictures  335 upvotes 1 year ago
      A user shared their successful hair loss treatment using RU58841, topical minoxidil, and microneedling, noting significant improvement over three months. They chose RU58841 over finasteride due to personal preference and reported no side effects, while others discussed their experiences with different treatments and supplements.

      community 5 months topical spiro + minox + micro

      in Progress Pictures  7 upvotes 1 year ago
      A 35-year-old male uses topical minoxidil, spironolactone, and microneedling for hair loss, with spironolactone prescribed based on a DNA test indicating poor response to finasteride and dutasteride. Despite concerns about the test's validity and spironolactone's side effects, he reports stable or improved hair condition and no low testosterone symptoms.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  4 upvotes 1 year ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

      community four months topical minoxidil update

      in Progress Pictures  13 upvotes 1 year ago
      The conversation is about a user's four-month progress using topical minoxidil for hair loss, with discussions on potential future use of finasteride and natural DHT blockers like saw palmetto and spearmint tea. The user is cautious about oral medications due to past side effects and is exploring natural alternatives.

      community Back from the dead! (Progress update)

      in Progress Pictures  998 upvotes 1 year ago
      A user shared their hair regrowth progress after a year of derma stamping, daily minoxidil, and four months of oral finasteride, along with regular workouts. Others discussed the effectiveness of these treatments and additional methods like red light therapy and RU58841.

      community My mum is mad annoying about Fin.

      in Chat  245 upvotes 2 years ago
      A 25-year-old man discusses his struggles with his mother's opposition to his use of Finasteride for hair loss treatment, despite it improving his condition and self-control after a hair transplant. He expresses frustration over her blaming the medication for various issues and the stress caused by her insistence to stop taking it.

      community Huberman tweet about finasteride

      in Finasteride/Dutasteride  278 upvotes 2 years ago
      The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

      community hmi115 is coming. Prepare yourselves for what's coming

      in Technology  106 upvotes 2 years ago
      The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

      community Diagnosed with female pattern hair loss as a male with recent aggressive loss. Preemptively mourning the only part of myself I’ve ever come close to loving. Lost all motivation to do anything with my life.

      in Progress Pictures  271 upvotes 2 years ago
      The conclusion of the conversation is that the user should consider using treatments such as finasteride, minoxidil, and RU58841 to potentially reverse their hair loss. Other suggestions include using hair loss concealers and maintaining a healthy diet.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  444 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community My Testosterone results before and after Finasteride

      in Update  147 upvotes 4 years ago
      Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

      community Why I deleted my YouTube channel Part I

      in Update  118 upvotes 4 years ago
      A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.