OP experienced significant hair regrowth after recovering from iron deficiency anemia and starting minoxidil. They suspect anemia contributed more to their hair loss than androgeneticalopecia (AGA).
Despite using dutasteride, RU58841, minoxidil, and ketoconazole for years, the user continues to experience severe hair loss and thinning. They seek advice after multiple dermatologists confirmed androgeneticalopecia (AGA) but offered no effective solutions.
A 26-year-old man from France started experiencing hair loss in September 2020 and began using finasteride in June 2021, reporting some improvement after three months without side effects. He plans to continue finasteride for a year before considering additional treatments like minoxidil or dermarolling.
The conversation discusses the effectiveness of reducing DHT for hair loss treatment and explores alternative approaches like reducing androgen receptor sensitivity. Specific treatments mentioned include finasteride, dutasteride, pyrilutamide (KX-826), GT20029, and RU58841.
The user experienced significant hair shedding after long-term use of finasteride and dutasteride and is now considering trying RU58841 as a last resort. They have checked health factors and suspect stress and poor sleep may contribute to the shedding, but they are determined to try RU58841 to see if it helps with androgeneticalopecia.
Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.
Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.
RU58841 is considered effective by some users, but finasteride and minoxidil are commonly used with varying dosages to manage side effects. Users report different experiences with treatments like pyrilutamide, fluridil, and RU58841, with some seeing results and others not.
The discussion revolves around the need for future oral DHT blockers for hair loss treatment that don't have the side effects of current options like Finasteride and Dutasteride. One user suggests that the future of hair loss treatment will likely be topical anti-androgens, as they can target hair follicles without affecting the entire system.
The conversation is about a person's positive experience with Dutasteride 1mg and Oral Minoxidil 2.5-5mg daily for Diffuse Unpatterned Alopecia, showing significant hair regrowth after 9 months. They mention a tough initial shedding phase, no side effects after 9 months, and a preference for oral treatments due to convenience and pet safety.
Topical Dutasteride may halt hair loss and effectively treat androgenicalopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.
A potential treatment for alopecia involving a protein that calms hair follicles has shown promise in rats, but skepticism remains about its applicability to humans. Many users express doubt about the timeline for effective hair loss treatments, comparing it to past unfulfilled promises.
The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.
A woman with androgeneticalopecia uses Dutasteride and Bicalutamide but feels devastated due to increased sensitivity to DHT. She considers wigs, Minoxidil, and seeks advice on options like spironolactone, hair transplants, and therapy.
RU58841 showed promise for treating androgenicalopecia but research was halted due to financial and organizational changes. There were no significant safety concerns reported in human trials.
A 27-year-old male with androgeneticalopecia has been using finasteride, topical minoxidil, and microneedling for over six months to stabilize hair loss and prepare for a potential hair transplant. While some users suggest switching to dutasteride and increasing minoxidil usage, others note minimal progress, with some hair stabilization but concerns about thinning at the crown.
A Spanish dermatologist suggests sulforaphane for androgeneticalopecia (AGA) due to its potential to remove DHT metabolites, though high dosages are needed. A topical formulation might be possible.
A user with seborrheic dermatitis and traction alopecia is seeking alternatives to minoxidil for hair loss, considering rosemary oil for its anti-inflammatory properties. They express concerns about potential side effects and effectiveness of various treatments, including rosemary oil, caffeine, and Redensyl.
Hair loss treatments for female pattern baldness, with the user focusing on wigs as an effective solution; they also discussed the difference between cheap and real wigs, and the importance of returning to confidence and self-esteem when tackling alopecia.
Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgeneticalopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.
A 20-year-old woman with androgeneticalopecia feels depressed about her hair loss, despite using topical minoxidil, spironolactone, and saw palmetto. Suggestions include trying oral minoxidil, higher doses of finasteride or dutasteride, and checking for vitamin deficiencies and heavy metal exposure.
Topical dutasteride with microneedling is effective for androgeneticalopecia, improving hair thickness and density. Further research is needed to confirm long-term efficacy.
A 30-year-old female with telogen effluvium and androgeneticalopecia is using spironolactone, oral minoxidil, vitamin D, iron sulfate, and a hairmax laser band. She seeks recommendations for a dermastamp or derma roller, advised to use no higher than 0.5 mm.
Minoxidil helped with hairline regrowth, but stopping it led to hair loss, suggesting circulation issues. Dermarolling, collagen peptides, and oils like castor and rosemary are recommended for improving hair health.
PP405 shows initial promise for treating androgeneticalopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.
The conversation is about Kintor's announcement indicating continued hope for their product KX-826 as a treatment for Alopecia Androgenetica. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.
Clascoterone 5% solution (Breezula) is a promising alternative for androgeneticalopecia, showing continued hair growth with consistent use and no significant side effects. It may be suitable for those who cannot tolerate finasteride or dutasteride, especially when trying to conceive.
A 36-year-old man with androgeneticalopecia suspects copper and zinc deficiencies may be accelerating hair loss and is supplementing copper to address this. He is also monitoring blood sugar levels due to previous prediabetes concerns and plans to test for insulin resistance.
Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.