A female user's diagnosis of androgenetic alopecia, and the advice shared in response which suggests taking spironolactone and minoxidil together to prevent hairloss.
The conversation discusses GT20029, a new topical drug for hairloss and acne without notable side effects, which has been accepted for investigational use in China. Some users express skepticism about the legitimacy of the company and the potential for other drugs like RU58841 to be developed due to patent expiration and lack of profitability.
The user experienced decreased libido with saw palmetto and is now considering topical anti-androgens like RU58841, pyrilutamide, and topical dutasteride for hairloss. Minoxidil is also mentioned as a potential addition, but the user is cautious about side effects and availability of treatments.
An 18-year-old male used anti-androgens and oral Minoxidil for 10 months to treat hairloss. He initially used 1mg Finasteride and 5% topical Minoxidil for 5 months, then switched to Dutasteride for 4.5 months and inconsistently used 5mg oral Minoxidil for 2 months due to availability issues.
The conversation discusses how Tretinoin may improve the effectiveness of Minoxidil for treating hairloss by increasing the activity of certain enzymes in hair follicles. One user comments that this information is not new.
Pyrilutimide and CB-03-01, two treatments for hairloss, have similar clinical trial results despite different binding affinities to androgen receptors. Factors other than binding affinity, like the time a drug stays bound to the receptor, may influence their effectiveness.
A 24-year-old male experienced an increase in estradiol levels and symptoms like gynecomastia and excessive sweating after using Minoxidil for hairloss. His estradiol levels decreased after he stopped using Minoxidil.
Minoxidil, finasteride, and RU58841 are suggested for hairloss treatment. Supplements like biotin and saw palmetto may help but are not effective for androgenic alopecia.
A woman experienced significant hair regrowth after six months of using dutasteride and minoxidil, despite initial hairloss due to androgenetic alopecia. She reported minimal side effects and highlighted the effectiveness of these treatments for women, despite doctors' hesitancy to prescribe them.
Consult a doctor before starting treatments like minoxidil and finasteride, as underlying issues like vitamin D deficiency can affect hairloss. While some believe androgenic alopecia is the most common cause, addressing all potential causes can lead to better results.
The conversation discusses the potential use of thermal paper receipts, which contain estrogen, as a treatment for hairloss. Participants humorously debate its effectiveness compared to established treatments like Minoxidil and finasteride.
The post and conversation are about the user's high testosterone levels and their worsening hairloss despite trying various treatments. They are considering using low doses of anti-androgens to lower their testosterone levels as a potential solution.
The user is taking dutasteride 0.5mg daily and seeks a topical androgen inhibitor for the scalp. They are looking for recommendations to enhance their hairloss treatment.
A 23-year-old has been using finasteride, dutasteride, and spironolactone to combat hairloss and hormonal acne, with mixed results and concerns about side effects. The user is experimenting with spironolactone despite its potential risks, hoping for skin and body hair improvements.
Dutasteride may inhibit androgen receptors in addition to reducing DHT, potentially explaining its effectiveness over finasteride for hairloss. Concerns about its impact on muscle growth are debated, with some suggesting no significant effects.
User used Finasteride, Dutasteride, and Minoxidil for one year to treat hairloss. They discussed possibly trying RU58841 or pyrilutamide in the future.
Kintor Pharma announced successful Phase II trial results for KX-826 in treating hairloss, showing it's comparable to finasteride and can be used with it. Some participants saw a 10 hair/cm^2 increase, which is considered a good outcome at the low dose used.
Bicalutamide blocks androgen receptors, preventing testosterone and DHT from binding, which can help with hairloss but may cause feminization. It is not recommended for those who do not want feminization effects.
A 26 year old female diagnosed with androgenetic alopecia who is interested in treatments such as spironolactone, finasteride and Minoxidil to help her hairloss but is worried about side effects like muscle gain, sex drive and effectiveness.
Spironolactone can remain effective for a long time in treating androgenetic alopecia, but it may not completely stop hairloss. Hairloss treatments like spironolactone, finasteride, and dutasteride slow down hairloss rather than cure it, and their effectiveness can vary based on individual response and the aggressiveness of the condition.
The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hairloss as they cannot tolerate anti-androgens and are also in therapy for mental health.
The user has been using finasteride, dutasteride, pyrithione zinc, and oral minoxidil to treat hairloss and has seen an increase in fine hairs on the hairline but overall thinning on the top. They are considering adding zinc and Vitamin K to their regimen and are already taking hair multivitamins with collagen.
The conversation discusses using 1% cetirizine, an antihistamine, as a potential treatment for androgenetic alopecia (hairloss). One user plans to try cetirizine instead of finasteride, while others are curious or skeptical about its effectiveness, discussing the role of inflammation in hairloss.
Ketoconazole shampoo is primarily used to reduce scalp fungus and inflammation, not to block DHT or androgen receptors. It may help with seborrheic dermatitis and improve scalp health, but its effects on hairloss are minimal compared to treatments like finasteride.
The user is using finasteride, minoxidil, and ciclopirox shampoo for hairloss and is considering adding a topical anti-androgen like RU58841, Clacosterone, or KX286. They have scheduled a hair transplant and are concerned about the cost and effectiveness of future treatments.
The post is about whether there is any additional benefit to using alfatradiol or other estrogen treatments for hairloss if someone is already using finasteride, dutasteride, or an androgen receptor inhibitor like RU58841, pyrithione zinc, or fluridil.
Kintor Pharma completed enrolling subjects for a Phase III trial of KX-826 for male hairloss treatment. The trial includes a 24-week treatment period and a 4-week safety follow-up, with results expected in about 6-7 months.
CB-03-01 is a topical anti-androgen with low absorption, offering potential as a side-effect-free alternative to Finasteride/Dutasteride for hairloss. It's in stage 2 clinical trials for acne and showing promise for male pattern baldness.
Certain oils and treatments used for natural breast enhancement, like fenugreek oil and shatavari, may also help with androgenetic alopecia due to their estrogen link. The discussion suggests these items might pause hairloss.