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      community GT20029 and PP405 the new fin and min that we been waiting for ?

      in Chat  36 upvotes 1 year ago
      PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

      community M20 Vitamin D Deficiency and Hair Thinning

      in General  75 upvotes 1 year ago
      A 20-year-old is experiencing hair thinning due to vitamin D deficiency and has completed a vitamin D prescription without seeing improvement. Suggestions include waiting a few months for potential regrowth or considering treatments like minoxidil or finasteride for androgenetic alopecia.

      community Anyone had anemia + AGA/thinning ?

      in Treatment  4 upvotes 1 year ago
      OP experienced significant hair regrowth after recovering from iron deficiency anemia and starting minoxidil. They suspect anemia contributed more to their hair loss than androgenetic alopecia (AGA).

      community Vitamin D deficiency - could it be the cause?

      in Update  6 upvotes 1 year ago
      The user is experiencing hair thinning and has a vitamin D deficiency, which they suspect might be causing the issue, but they are also considering androgenic alopecia (AGA) as a cause. They are currently using minoxidil and are unable to get finasteride prescribed, while others suggest addressing the vitamin D deficiency and consulting a dermatologist.

      community Ru58841 made my hair worse

      in General  138 upvotes 1 year ago
      RU58841 worsened hair condition, causing thinning and unusual patterns. The user stopped using it two months ago but hasn't seen recovery, and there's speculation about androgen receptor upregulation.

      community 2 months apart, Are these bumps follicles?

      in Is this regrowth?  9 upvotes 1 year ago
      The user is using a mix of supplements, including Minoxidil, to address androgenetic alopecia and is concerned about zinc dosage potentially causing issues. They plan to discuss their treatment and supplement regimen with a dermatologist.

      community Lots of shedding after adding bica 50 mg daily

      in Transgender  119 upvotes 1 year ago
      Switching from spironolactone to bicalutamide caused severe hair shedding, despite using treatments like dutasteride, minoxidil, and estradiol injections. The user is experiencing androgenetic alopecia and is seeking solutions to stop the hair loss.

      community Read before embarking on your hair recovery journey

      in Treatment  207 upvotes 1 year ago
      Consult a doctor before starting treatments like minoxidil and finasteride, as underlying issues like vitamin D deficiency can affect hair loss. While some believe androgenic alopecia is the most common cause, addressing all potential causes can lead to better results.

      community 22M - Doctor Said Hair Loss From Stress, Minoxidil Helped But Now It’s Back Worse. What Now?

      in General  117 upvotes 1 year ago
      A 22-year-old experiencing hair loss, initially attributed to stress, found temporary relief with minoxidil but faced increased shedding after stopping and restarting the treatment. The advice given suggests the hair loss may be due to androgenic alopecia rather than stress, recommending consistent use of minoxidil and considering finasteride, with a suggestion to seek a second opinion from another dermatologist.
      Do I have a chance of reversing this without a transplant?

      community Do I have a chance of reversing this without a transplant?

      in General  98 upvotes 1 year ago
      A 19-year-old is seeking advice on reversing hair loss without a transplant, currently using oral finasteride and topical minoxidil. A suggestion was made to switch to dutasteride and use a stronger minoxidil, with the addition of a topical anti-androgen after three months.

      community 30 Female, a month into 5% Minoxidil - is this normal?

      in Female  30 upvotes 1 year ago
      A 30-year-old woman experiencing rapid hair loss is using 5% Minoxidil, Saw Palmetto, vitamins, and Nizoral, but is advised to see a dermatologist as her symptoms may indicate a condition other than androgenetic alopecia, such as alopecia areata or a thyroid issue. Many suggest a biopsy and blood tests to determine the underlying cause.

      community Koshine comes under two names apparently

      in Product  1 upvotes 1 year ago
      The conversation is about receiving a shipment of Koshine, also known as Kintor, which is an anti-androgen treatment for hair loss. The user is eager to try the KX-826 product and observe its effects and any side effects.

      community Hair journey since august, help!

      in Is this regrowth?  22 upvotes 1 year ago
      The conversation is about hair loss and treatments, with suggestions to use finasteride or dutasteride as DHT blockers and minoxidil for regrowth. Oils and shampoos are considered ineffective for androgenic alopecia without these medications.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Revalid hair complex against hair thinning?

      in Product  3 upvotes 1 year ago
      A 17-year-old with thinning hair is considering using Revalid, a supplement with ingredients like biotin and zinc, based on parental recommendations. Another user suggests that supplements could help since the hair thinning doesn't seem to be androgenic alopecia.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community New angles to attack beyond DHT

      in Research/Science  4 upvotes 1 year ago
      Exploring hair loss treatments beyond DHT, including Minoxidil, pyruvate, Gt20029 targeting androgen receptors, and vasodilators. Other options like Kx826, adenosine signaling, growth factor topicals, and microneedling are also discussed.

      community Koshine826 - LX-826? machine translation of the news article

      in Product  5 upvotes 1 year ago
      KOSHINE826 is a new anti-hair loss and hair growth solution that claims to effectively control oil, reduce hair fall, and promote real hair growth. It targets androgenetic alopecia by inhibiting DHT and has shown promising results in clinical trials.

      community AGA responded to steroid shots? Biopsy wrong? Please help!

      in Female  2 upvotes 2 years ago
      A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

      community Leaving Ketoconazole Shampoo on for Longer

      in Ketoconazole  15 upvotes 2 years ago
      The conversation is about using Ketoconazole shampoo for hair loss, with users discussing leaving it on the scalp for longer periods. Some users report benefits for dandruff, but there's uncertainty about its effectiveness for androgenetic alopecia (AGA).