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      community Spironolactone and pregnancy planning

      in Female  2 upvotes 1 year ago
      A user with AGA uses topical spironolactone 2% due to side effects from the oral form and is concerned about its use during conception and breastfeeding. They seek alternatives to prevent AGA relapse while planning pregnancy and after childbirth.

      community Low dose spiro with 5ARI inhibitor

      in Chat  2 upvotes 1 year ago
      Spironolactone, finasteride, and dutasteride are discussed for hair maintenance, with concerns about testosterone and side effects like gynecomastia. Spironolactone is noted for use in both bodybuilding and hormone therapy, with low doses considered for minimizing side effects.

      community Thinking about using PP405 and RU58841

      in Research/Science  1 upvotes 5 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.

      community Female male-pattern AGA- seeking help

      in Female  1 upvotes 2 years ago
      A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.

      community RU58841 is the only thing that worked for me, a DUPA sufferer

      in Treatment  1 upvotes 11 months ago
      RU58841 was the only treatment that slowed hair loss and reduced irritation for a DUPA sufferer after trying finasteride, minoxidil, and dutasteride with no success. The user continues using 6mg oral minoxidil, 0.5mg dutasteride, and an 8% RU58841 solution.

      community 7 months progress. fin 1.25 mg, oral min 2.5 mg, keto shampoo, micro-needling once per month. M/32

      in Progress Pictures  82 upvotes 2 years ago
      A user shared a 7-month hair loss treatment progress using finasteride 1.25 mg, oral minoxidil 2.5 mg, ketoconazole shampoo, and monthly micro-needling, noting denser hair and improved quality but no significant regrowth. They experienced mild testicular discomfort and heart palpitations, considering switching to topical minoxidil to avoid side effects.

      community Anyone tried topical adenosine?

      in Product  4 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. User asks for opinions on topical adenosine as a treatment.

      community Anyone tried adenosine for hair loss? Share your experience

      in Treatment  3 upvotes 3 months ago
      A user is seeking experiences with adenosine for hair loss, asking about its effectiveness, usage duration, and combination with treatments like minoxidil, finasteride, or RU58841. Another user mentions difficulty sourcing adenosine and comments on the mixed quality of research.

      community GT20029 Big Phase 2 Update Results!

      in Research/Science  52 upvotes 6 months ago
      GT20029 showed promising results for hair growth in a Phase II trial, with the 1.0% twice-weekly regimen being the most effective. Some users expressed skepticism and humor about the product's effects and market availability.

      community Tretinoin in Androgenic Alopecia

      in Research/Science  12 upvotes 3 years ago
      The conversation discusses using Tretinoin for treating androgenic alopecia. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

      community Multi-Peptide Serum for Hair Density - The Ordinary

      in Treatment  1 upvotes 1 year ago
      The user reports positive results using a multi-peptide serum for hair density, combined with finasteride and melatonin, after stopping minoxidil. They experienced hair regrowth after previously losing hair despite using finasteride and minoxidil.

      community Twist1 Group Buy: Yes it’s that easy

      in Research/Science  39 upvotes 3 years ago
      A group buy for testing a compound targeting Twist1 protein as a potential hair loss treatment. Inhibiting Twist1, which keeps hair follicles in growth phase, may prevent hair loss with minimal side effects.

      community Galenic lotion. Science behind the components

      in Treatment  1 upvotes 10 months ago
      A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

      community I Get Side-Effects from Anti-Androgens

      in Finasteride/Dutasteride  8 upvotes 5 years ago
      Someone looking for solutions to their hair loss, who has tried and failed to tolerate anti-androgen treatments such as finasteride, CB-03-01, RU58841, and Eucapil. The user is seeking advice and understanding of their extreme sensitivity to these treatments.

      community TresslessGPT is available to ChatGPT Plus users

      in 📣 Announcement  107 upvotes 2 years ago
      The conversation introduces a specialized chatbot for ChatGPT Plus users that provides advice on hair loss treatments, drawing from research and community insights. It mentions treatments like RU58841, the "big 4" (likely minoxidil, finasteride, ketoconazole, and tretinoin), dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

      community 7 Month Progress and still growing. Minoxidil + Finasteride

      in Progress Pictures  15 upvotes 6 months ago
      The user experienced significant hair regrowth using 1 mg finasteride daily and 5% topical minoxidil once a day over seven months, with minor side effects like hypertrichosis. Consistency in treatment was emphasized, and the user reported improved hair density and texture without major side effects.

      community 8 monts progress 1mg fin 5mg min

      in Progress Pictures  20 upvotes 1 month ago
      The user experienced increased hair density and improved hairline definition after 8 months of using 1mg finasteride and 5mg minoxidil (both oral and topical) daily, though the hairline recession hasn't reversed. They noticed fuller eyelashes and increased shedding, but overall hair growth is outpacing the loss.

      community Oral Minoxidil - The Hyper-Responder Concept

      in Research/Science  5 upvotes 7 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community risks with finasteride and dutasteride

      in Research/Science  141 upvotes 11 months ago
      Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

      community (Europe) looking for advice on topical anti androgen use

      in Treatment  3 upvotes 10 months ago
      The user is using finasteride, minoxidil, and ciclopirox shampoo for hair loss and is considering adding a topical anti-androgen like RU58841, Clacosterone, or KX286. They have scheduled a hair transplant and are concerned about the cost and effectiveness of future treatments.