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      community Combine minoxidil, tazarotene, lumigan

      in Treatment  3 upvotes 11 months ago
      Combining minoxidil 5%, tazarotene 0.1% cream, and lumigan for hair loss treatment is discussed. The conversation focuses on the safety and effectiveness of using these treatments together.

      community 25M Seeking Advice on Hair Regrowth Treatments and Options

      in Basic Questions  123 upvotes 1 month ago
      A 25-year-old is considering treatments for hair regrowth, including ketoconazole shampoo, 5% Minoxidil, Minoxidil with Tretinoin, and possibly ordering RU58841. They are hesitant about using Dutasteride or Finasteride due to perceived risks but are motivated to regrow hair to improve appearance due to visible veins from low body fat.

      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  13 upvotes 5 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community Anti Fibrosis and Calcification regimen?

      in Question  10 upvotes 8 years ago
      The user experienced no improvement in hair loss with finasteride and minoxidil but had side effects. They plan to add wounding, scalp massage, vitamin K, and taurine supplements to their regimen and seek feedback on these additions.

      community Liquid minoxidil + pyrilutamide

      in Treatment  17 upvotes 3 years ago
      Potential treatments for hair loss, specifically the combination of liquid minoxidil and pyrilutamide, with some suggesting that adding finasteride may be beneficial.

      community An updated, simple guide to the most effective hair loss treatments

       193 upvotes 6 years ago
      Effective treatments for hair loss, including Dutasteride, Finasteride, Minoxidil, Dermarolling, LLLT, PRP, Ketoconazole, and Scalp Massage. In addition, anti-inflammatory diets and stress management are recommended to maintain or regrow hair.

      community What do you guys think about my foundation?

      in Treatment 5 months ago
      The user had a hair transplant and uses oral minoxidil, a red laser therapy helmet, fish oil, collagen, and sardines for hair thinning but avoids finasteride due to side effect concerns. Many suggest these methods may not be effective long-term without a DHT blocker.

      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 7 months ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

      community My nuclear protocol (scary but very effective)

      in Treatment  80 upvotes 4 years ago
      A hair loss treatment protocol involving topical and oral medications such as Minoxidil, RU58841, Finasteride, Dutasteride, Melatonin, Zinc, Vitamin B6, NAC, Caffeine, Biotin, Ginseng, and Semen; other treatments including Microneedling, Laser Helmet, Nizoral shampoo, Scalp Massage and supplements like Vitamin C, Vitamin D, Fish Oil, and Biotin; and the potential side effects of using this protocol.

      community Verteporfin day 119 update - donor hair regeneration human trial

      in Research/Science  146 upvotes 3 years ago
      A human trial of verteporfin, a drug that can inhibit wound healing by scarring and promote regeneration of original tissue and hair follicles to provide an unlimited source for hair transplants; people discussed the potential of this drug and how it could be rolled out in mainstream with more doctors getting on board.

      community Can amino acids help with AGA

      in Chat  4 upvotes 2 years ago
      Amino acids like lysine, methionine, and cysteine may help with androgenetic alopecia when taken in high doses along with a DHT blocker. Users discuss combining these with treatments like Minoxidil, finasteride, and RU58841.

      community When dutasteride does not slow down hairloss

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The conversation is about a user struggling with hair loss despite using dutasteride, finasteride, minoxidil, and dermaneedling. The user is considering other treatments but is hesitant to use RU-58841 due to side effects and is seeking advice on alternative solutions.

      community NW5 advice current treatments AGA

      in Treatment  5 upvotes 5 years ago
      Minoxidil, PRP, low-level light therapy, stem cell therapy, mesotherapy, Acell, and microneedling are discussed as treatments for thickening fine hairs in NW5 hair loss sufferers. A hair transplant may be necessary for significant improvement.

      community Proposed Alternative stack to fin/min combination

      in Treatment 1 year ago
      A user proposed an alternative hair loss treatment stack using topical caffeine, copper, microneedling, and red light as a natural option for those experiencing side effects from finasteride or minoxidil. Other users expressed skepticism, emphasizing that finasteride and minoxidil remain the most effective treatments, while the proposed alternatives are unlikely to provide long-term results.

      community We Need A Solution For The Inflammatory Response related To AGA

      in Research/Science  16 upvotes 1 year ago
      The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

      community only microneedling and supplements

      in Progress Pictures  67 upvotes 10 months ago
      The user used microneedling, zinc, vitamin D3, biotin, magnesium, saw palmetto, pumpkin seed oil, and a DHT-blocker shampoo with biotin for hair loss. They are considering adding minoxidil due to stagnation in progress.

      community Proposed new pathogenesis model for androgenetic alopecia (AGA)

      in Research/Science  7 upvotes 3 years ago
      The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Thoughts on Avixis Alfatradiol?

      in Product  4 upvotes 4 years ago
      Avixis Alfatradiol is a topical 5-alpha reductase inhibitor available in Latin America and Germany, but its effectiveness is questioned. A user reported worsened hair loss after using it and recommended finasteride instead due to its proven effectiveness and lower cost.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.