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960-990 / 1000+ resultscommunity PP405 is still being evaluated for safety over efficacy.
Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss. PP405 is still under evaluation for safety.
community Is there a consensus on RU these days? Pyril turned out to be a bust right?
The conversation discusses the effectiveness and safety of hair loss treatments, specifically RU58841 and Pyrilutimide (Pyril), with users sharing that Pyril was no more effective than a placebo and expressing concerns about the safety of RU58841 based on personal experiences and the lack of pharmaceutical interest.
community B12 and D Vitamins very low (bloodwork showed 15 for D). Dutasteride and Minoxidil not holding back the hairloss. Should i supplement?
Dutasteride and Minoxidil are not effectively preventing hair loss. Supplementing with Vitamin D and B12 is recommended.
community Pyrilutamide - anybody getting real gains from it?
People's experiences with Pyrilutamide as a hair loss treatment, including anecdotal evidence of regrowth and reduced scalp itch when used in conjunction with Finasteride and Minoxidil.
community Are these a good on, what’s your opinion?
Progesterone, hydrocortisone butyrate, and estrone base are discussed as treatments for hair loss. Topical progesterone and dutasteride are suggested to potentially reverse androgenic alopecia.
community RU58841 2.5% in Minoxidil 5% 3ml twice a day - Less Hairfall "BUT"
The user mixed RU58841 with Minoxidil for hair loss treatment and experienced reduced hair fall and thicker hair but stopped due to chest pain and muscle twitching. They plan to use a new routine without RU58841 or Finasteride due to side effects, including various topical treatments and peptides.
community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease
Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.
community 24 y/o woman diagnosed with AGA today. Scared and confused.
A 24-year-old woman being diagnosed with androgenic alopecia (AGA) who is scared and confused about her hair loss, and the treatment options of Minoxidil, finasteride, RU58841, spironolactone, and possibly a biopsy.
community I tried mixing 3 grams RU58841 into 60ml minoxidil 5% solution and shook for 5 minutes and I can still see tiny crystals floating around like a snow globe when I shine a torch in the bottle
OP mixed RU58841 with minoxidil and initially saw crystals, but realized they were bubbles. They asked for advice on application frequency for a 5% solution.
community Histamine intolerance and topical treatments
The user experiences histamine intolerance with alcohol-based hair loss treatments like Rogaine foam and seeks alternatives. Suggestions include alcohol-free and PPG-free topical minoxidil or finasteride, and trying Spectral products with different solvents.
community kx826 .05% month 8 | topical minoxidil .5% month 21 combo update.
The user used finasteride but stopped due to side effects, then used topical minoxidil for 13 months, and later added KX826/pyrilutamide for 8 months. They experienced shedding after starting pyrilutamide and use minoxidil and KX826 once daily.
community How long until pyrilutamide or gt20029 get FDA approved?
Hair loss treatments pyrilutamide and GT20029 discussed. Pyrilutamide approval in 2 years, GT20029 in 5-6+ years.
community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution
The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.
community ghk-cu is potent 5-ar inhibitor?
GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.
community Pyrilutamide 2 months update(with pics )
The conversation discusses the effects of Pyrilutamide on hair growth after two months, with one person noting that while new hair regrowth isn't apparent, existing hair appears longer and thicker.
community On Dutasteride 0.5mg ED for almost 2 years. Increasingly shedding hair for more than 5 months.
The user experienced increased hair shedding after switching from finasteride to dutasteride, despite lifestyle improvements and additional treatments like oral minoxidil and PRP. They are concerned about persistent shedding, changes in hormone levels, and potential chronic telogen effluvium, and are considering a scalp biopsy for further investigation.
community Is pyri and gt20029 worth the hype????
The conversation discusses the effectiveness of pyrithione zinc and GT20029 for hair loss. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.
community Where are GT20029 phase II results?
The conversation is about the anticipation of results for a hair loss treatment study, specifically for GT20029, with expectations for the results to be released in the first quarter of 2024. No specific treatments were discussed.
community Planning to take a break from Fin for a 2 months then start with Pyrilutamide - What hormone levels to test?
The user plans to pause finasteride for two months to test its effects on mood and productivity, then switch to Pyrilutamide while monitoring hormone levels. Concerns are raised about potential hair loss and the effectiveness of Pyrilutamide compared to finasteride.
community Adrogens and Covid-19
The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.
community 26 months of finasteride—> below baseline
The conclusion of the conversation is that the user, General-Switch-5722, has been using finasteride and minoxidil for over 2 years but is still experiencing hair loss. They are considering adding a low dose of RU58841 or topical dutasteride as potential treatments. Other users in the conversation have suggested switching to dutasteride or using oral minoxidil.
community Anyone tried switching from RU to Pyrilutamide (KX-826)
The conversation discusses switching from RU58841 to pyrilutamide for hair loss treatment, with users generally recommending staying on RU58841 if it is effective. RU58841 is sourced from GeneTherica, which ships worldwide.
community Topical Finasteride: 130 Day Update
The user tried a home-brew topical finasteride regimen for 120 days with initial benefits but no long-term improvement, leading to continued hair shedding. They switched to oral finasteride, experiencing mild testicle discomfort but no changes in libido or erections, and plan to continue this regimen for 120 days.
community 0.025% tretinoin strong enough to enhance minoxidils effects?
Using 0.025% tretinoin may enhance minoxidil's effects for hair loss. Users suggest starting with 0.025% and gradually increasing the concentration, and discuss combining treatments like microneedling.
community Shedding long hair after 8 months of no shedding (oral dut .5mg+ oral min 2.5)
A user experienced significant hair shedding after 8 months of using oral dutasteride (0.5 mg), minoxidil (2.5 mg), and biotin (5 mg) daily. They are concerned about the effectiveness of the treatment and possible resistance to dutasteride.
community I interviewed Kintor: GT20029 Clinical Trial Pictures. As well as KX826.
GT20029 and KX826 are promising hair loss treatments, with GT20029 increasing hair count and KX826 showing significant results. KX826 may be a good alternative for those who can't use finasteride or dutasteride, though results vary.
community Does the HMI-115 actually have potential or is it another false hope?
Hair loss discussion includes potential HMI-115 treatment. Topical mucuna pruriens shows good results, blocking prolactin possibly more important than blocking DHT.
community Epidemic of brand names working wildly different, if at all.
The conversation discusses the variability in effectiveness of medications, including finasteride, and questions whether different manufacturers impact results. The user suggests sharing successful brands to help others identify effective options.
community Pyrilutamide just launched internationally, and all you're doing is hating
The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.