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      community Clascoterone 5% solution infographic

      in Update  132 upvotes 6 months ago
      Clascoterone 5% solution is discussed as a potential new treatment for hair loss, offering an alternative for those who can't use finasteride or need additional options beyond minoxidil. Concerns about cost, effectiveness, and safety compared to existing treatments like RU58841 and finasteride are highlighted.

      community Are there alternatives to finasteride?

      in Research/Science  12 upvotes 3 years ago
      The conversation is about seeking alternatives to finasteride for hair loss treatment due to concerns about sexual side effects, with pyrilutamide mentioned as a potential alternative.

      community Any alternatives to topical min?

      in Treatment  1 upvotes 11 months ago
      The user is considering alternatives to topical minoxidil for hair growth due to concerns about future cat ownership, mentioning stemoxydine and redensyl as possibilities. They currently use topical regaine foam and oral finasteride.

      community About those dutasteride studies 😒

      in Research/Science  24 upvotes 1 year ago
      Dutasteride studies for hair loss are often sponsored by GlaxoSmithKline, raising concerns about potential bias. Despite this, some users report positive results with dutasteride and oral minoxidil, while others remain skeptical of industry-funded research.

      community Oral minox + dut

      in Research/Science  8 upvotes 5 years ago
      The conversation discusses hair loss treatments using oral minoxidil, oral dutasteride, and mesotherapy dutasteride, showing impressive 6-month results. The user wishes these treatments were available in the U.S.

      community Dutasteride not working - is it the end?

      in Finasteride/Dutasteride  2 upvotes 1 month ago
      The user tried topical minoxidil, topical and oral finasteride, and switched to dutasteride and oral minoxidil without success in stopping hair loss. Suggestions included continuing treatment longer, trying microneedling, and considering a hair transplant.

      community Does the effect of spironolactone on androgenetic alopecia really weaken over time?

      in Female  4 upvotes 1 year ago
      Spironolactone can remain effective for a long time in treating androgenetic alopecia, but it may not completely stop hair loss. Hair loss treatments like spironolactone, finasteride, and dutasteride slow down hair loss rather than cure it, and their effectiveness can vary based on individual response and the aggressiveness of the condition.

      community My dermatologist uses oral minox and dutasteride

      in Minoxidil  65 upvotes 3 years ago
      Treatments for hair loss and the potential side effects. The user discussed their doctor's advice to take 1.25 mg oral minoxidil and .5 mg dutasteride daily, with a warning that those with heart conditions should not take oral minoxidil. Other users shared their experiences, including taking finasteride and noting the possible overkill of the dosage prescribed by Jirons1's dermatologist.

      community DHT is about to get smashed ….

      in Update  801 upvotes 1 year ago
      The conversation discusses hair loss treatments like topical finasteride with minoxidil, oral dutasteride, and essential oils. Oral treatments like dutasteride and finasteride are seen as more effective, though some prefer topicals to avoid side effects.

      community I’m taking Veradermics VDPHL01 - AMA

      in Treatment  174 upvotes 1 month ago
      A participant using Veradermics VDPHL01, an extended-release oral minoxidil, experienced significant hair regrowth from Norwood 6 to Norwood 3V without side effects. They plan to use dutasteride after the treatment to maintain results.

      community Dutasteride mesotherapy alongside oral fin and dut?

      in Research/Science  2 upvotes 5 months ago
      Dutasteride mesotherapy, combined with peptides and exosomes, is being considered for hair loss treatment. One user suggests that oral finasteride or dutasteride mesotherapy may not be necessary if already taking oral dutasteride.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Got prescribed Dutasteride today

      in Treatment  13 upvotes 2 years ago
      The conversation is about someone being prescribed Dutasteride for hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

      community Hypertrichosis goals (yes, yes R2M)

      in General  115 upvotes 1 year ago
      The user aims to achieve a hypertrichosis look and has used topical Minoxidil for 20 years, now trying oral Minoxidil in a low dose. They seek alternatives to Minoxidil to avoid side effects.

      community Topical fin working when oral has failed?

      in Finasteride/Dutasteride  1 upvotes 2 years ago
      The user switched from oral finasteride to dutasteride with minoxidil, but saw no results. They then tried topical finasteride and noticed some potential improvement after four months, theorizing that the topical application bypasses liver metabolism.

      community Hairline itch when hairline’s receding

      in Chat  80 upvotes 7 months ago
      Hair loss treatments like finasteride, dutasteride, minoxidil, and RU58841. Users discuss "DHT itch" at receding hairlines and suggest using dutasteride or ketoconazole shampoo for relief.

      community What makes breezula different than formula 82f?

      in Question  9 upvotes 6 years ago
      Breezula (clascoterone) and Formula 82F (topical finasteride) are treatments for hair loss that block DHT differently; Breezula competes with DHT at the hormone receptor site without systemic effects, while 82F inhibits the enzyme that converts testosterone to DHT. Breezula may work for those who don't respond to finasteride and vice versa.