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      community Binding affinity of pyrilutamide!

      in Update  168 upvotes 4 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Experiencing Shedding on Phoenix 2in1 and Nizoral for 9 Months

      in Basic Questions  75 upvotes 1 month ago
      The user has been using a Phoenix 2-in-1 pill (1mg finasteride with 3mg minoxidil), nizoral ketoconazole shampoo, and derma rolling for 9 months but continues to experience hair shedding. They are considering adding Rogaine foam and are curious about low-level laser caps for better results.

      community Nizoral ketaconazole any good for dht reduction

      in Ketoconazole  8 upvotes 5 years ago
      A 17-year-old is looking for alternatives to finasteride for DHT control to preserve hair, considering ketoconazole shampoo for its potential to inhibit 5AR and also thinking about using caffeine-containing shampoos like alpecin or watermans.

      community Any male on topical spironolactone?

      in Research/Science  7 upvotes 6 months ago
      Topical spironolactone is discussed for hair loss treatment, with mentions of DIY solutions and dermatologist compounding. Users inquire about regrowth and sourcing the treatment.

      community Dandruff and Topical Solutions

      in Finasteride/Dutasteride  2 upvotes 2 years ago
      The user is using a topical solution with finasteride, minoxidil, and retinoic acid, which causes scalp residue and dryness. They seek advice on removing residue and keeping the scalp moisturized.

      community Anyone had success with homemade topical Spiro?

      in Female  2 upvotes 1 year ago
      A user is using homemade topical spironolactone for androgenetic alopecia and is unsure about its effectiveness due to concurrent telogen shedding. They are seeking advice on others' experiences with homemade topical spironolactone.

      community What are these spots on my scalp

      in Treatment  51 upvotes 1 year ago
      A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

      community Pre and Post Dermarolling Routine?

      in Microneedling  18 upvotes 5 years ago
      The conversation is about a hair loss treatment routine involving dermarolling, finasteride, minoxidil, and natural oils. Suggestions include using shorter needles for better absorption of treatments and longer needles less frequently for hair follicle regeneration.

      community found out im more responsive to dutastetide than finasteride

      in Finasteride/Dutasteride  20 upvotes 3 years ago
      The user switched from finasteride to dutasteride for hair loss and saw significant improvement in under two months. They also microneedle, take supplements including collagen and vitamin D3, use ketoconazole shampoo, and noticed accidental hair regrowth with retinol application on their face.

      community Progress with low-dose topicals

      in Research/Science  4 upvotes 2 months ago
      The conversation discusses using low-dose topical finasteride, specifically 0.005% and 0.01%, for hair regrowth, with some users considering increasing the concentration for better results. Users share experiences with different dosages and combinations, including minoxidil, and discuss the effectiveness and availability of these treatments.

      community Can’t take fin - options/alts?

      in Finasteride/Dutasteride  6 upvotes 4 years ago
      User seeks non-finasteride hair loss treatments, suggests Eucapil, minoxidil, microneedling, keto shampoo, oral castor oil, and alfatradiol. Reply recommends vitamin D, zinc, pumpkin seed oil, saw palmetto, and high black tea intake, but emphasizes minoxidil and microneedling as most effective.

      community Terminal hairs growing in, but derm still says I’m going to go bald in the years to come??

      in Chat  5 upvotes 1 year ago
      A 30-year-old woman with a history of anemia and low vitamin D experienced hair shedding, which improved after addressing nutrient deficiencies. Despite regrowth of terminal hairs, her dermatologist recommended treatments like minoxidil and spironolactone to prevent future bald spots, but she is cautious due to family history of hormone-related cancers.

      community Why haven’t we seen anything about this

      in Research/Science  18 upvotes 6 years ago
      A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.

      community Any Microneedling non-responders figure it out by experimenting?

      in Microneedling  1 upvotes 7 months ago
      The conversation discusses experimenting with microneedling for hair loss, specifically addressing non-responsiveness and the use of topical treatments like dutasteride, minoxidil, and tretinoin. The user seeks advice on effective frequency and depth combinations for better results.

      community Few questions about my futur treatment

      in Treatment  3 upvotes 2 years ago
      The user, who experienced hair loss at the temples due to psoriasis at 17, is now 21 and considering treatment options. They are inquiring about using minoxidil once a day, whether non-AGA hair loss will persist after stopping minoxidil, and if alternative remedies like Detumescence therapy, rosemary and peppermint oils, and microneedling could be sufficient.

      community Topical Dutasteride & Microneedling Works

      in Finasteride/Dutasteride  7 upvotes 1 year ago
      Topical dutasteride, especially at higher concentrations, can be effective for hair loss when combined with microneedling to enhance absorption. Users discuss the side effects of finasteride and dutasteride, with some preferring topical treatments to avoid systemic side effects.

      community Actually making progress, I think.

      in Is this regrowth?  66 upvotes 2 years ago
      User reports seeing fast hair regrowth after 1 month and 12 days using 0.3% Finasteride and 6% Minoxidil. They are considering microneedling and received advice to use a derma stamp.

      community Pp405 full presentation on new topical

      in Product  105 upvotes 2 months ago
      A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.