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community for those who had high levels of testo and estradiol after start fin/dut: did it comeback to baseline or normal levels?

in Finasteride/Dutasteride 8 upvotes 1 year ago

A user experienced increased testosterone and estradiol levels after starting finasteride/dutasteride and is asking if these levels will return to normal over time. The conversation focuses on whether these changes are temporary.

community Bloodwork after 18 months on finasteride (1 year on dut + fin)

in Finasteride 5 upvotes 6 years ago

The user has been on finasteride for 18 months and added dutasteride after the first 6 months, with no hair regrowth observed. Bloodwork shows normal levels of DHT despite the use of both medications.

community We need to talk about DHT itch

in Treatment 3 years ago

DHT Itch and its link to balding, with various treatments such as finasteride being discussed. Members shared their experiences of scalp itch before and after taking 5AR inhibitors, and potential underlying causes such as seborrheic dermatitis were discussed.

community Is this hierarchy of topical anti androgens accurate?

in Ketoconazole 7 upvotes 3 years ago

User on fin, minox, and ketoconazole seeks to add another topical anti-androgen. Hierarchy of effectiveness: 1. RU55841, 2. Fluridil - Eucapil, 3. CB-03-01 - Breezula, 4. Ketoconazole; alfatradiol suggested as addition.

community KX-826 1% Phase II Results from China Just Dropped

in Research/Science 37 upvotes 8 months ago

KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

community There is news from pyrilutamide?

in Product 32 upvotes 2 years ago

The discussion is about a hair loss drug called pyrilutamide. Users discuss its efficacy, safety, and expected market release around 2025-2026, with some expressing concerns about the authenticity of current market offerings.

community Dut + Min, 5 Months In, No Results — Need Advice

in Treatments 163 upvotes 7 months ago

A 28-year-old experiencing worsening hair loss despite using Dutasteride and oral Minoxidil is considering exosome therapy and possibly switching treatments due to side effects. They seek advice on whether to continue with Dutasteride or try alternatives like Pyrilutamide or topical supplements.

community Halted my hair loss with topical liposomal finasteride 0.01%

in Treatment 22 upvotes 7 months ago

The user halted hair loss using 0.01% topical liposomal finasteride daily, with no side effects or regrowth, and recently added 5% minoxidil and low-level laser therapy. They recommend this conservative approach for those hesitant about finasteride.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 2 years ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community Dim: high estradiol levels what to do

in Chat 8 upvotes 1 year ago

A user is experiencing facial bloating from low-dose topical finasteride due to high estradiol levels and is seeking advice on using DIM to manage this issue, including dosage and brand recommendations.

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