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      community What is worth dissolving in topical minoxidil solution?

      in Treatment  3 upvotes 1 year ago
      Switching from minoxidil foam to topical solution and considering adding caffeine, melatonin, or cetirizine. Currently using 2.5mg oral minoxidil and 1mg oral finasteride, planning to ask for 0.5mg oral dutasteride and 5mg oral minoxidil.

      community Fluridil degrades the androgen receptor.

      in Research/Science  12 upvotes 10 months ago
      Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.

      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 2 years ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

      community Fallopia multiflora (Fo-Ti) for Hair Regrowth?

       3 upvotes 12 years ago
      Fo-Ti is discussed as a potential treatment for hair loss, but its effectiveness is questioned. Users express skepticism and caution about its use.

      community Topical finasteride might be a lie

      in Research/Science 2 years ago
      The conversation discusses doubts about the effectiveness of topical finasteride for hair loss, suggesting that DHT could be produced elsewhere in the body and affect the scalp. It proposes that androgen receptor antagonists like spironolactone and clascoterone might be more effective as they could prevent this potential bypass mechanism.

      community Minox and retinol? Does it work better?

      in Product  2 upvotes 1 year ago
      A user has been using minoxidil and finasteride for hair loss for about five years, noticing that while it hasn't improved much, it has slowed hair loss. They recently added topical retinol, which seems to have increased hair growth, possibly by enhancing minoxidil absorption and activity.

      community Is it possible for diffuse thinning to stop or retard?

      in Finasteride/Dutasteride  11 upvotes 4 weeks ago
      Diffuse thinning is unpredictable, and while some suggest treatments like finasteride or dutasteride, others emphasize acceptance as hair loss may continue. Some users share personal experiences with treatments like nizoral, scalp massage, and lifestyle changes, but results vary.

      community Dutasteride 0.05% topical vs Finasteride 0.1% topical foam

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      The conversation discusses two hair loss treatments: Minoxidil 5% with Azelaic Acid 1.5% and Dutasteride 0.05% topical foam, and Finasteride 0.1% with Minoxidil 5% topical foam. Users express uncertainty about the effectiveness of topical Dutasteride, while topical Finasteride is generally considered effective.

      community Minoxidil foam and styling products

      in Minoxidil  2 upvotes 11 months ago
      Minoxidil foam can be used with styling products, but it's best to wait before applying fibers. Switching to night application may help maintain hairstyle.

      community Still hope on Kintor due to the new announcement

      in Treatment  17 upvotes 2 years ago
      The conversation is about Kintor's announcement indicating continued hope for their product KX-826 as a treatment for Alopecia Androgenetica. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community Topical fin working when oral has failed?

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The user switched from oral finasteride to dutasteride with minoxidil, but saw no results. They then tried topical finasteride and noticed some potential improvement after four months, theorizing that the topical application bypasses liver metabolism.

      community started RU58841 today and am panicing

      in Treatment  8 upvotes 2 years ago
      A user started using RU58841 for hair loss and experienced anxiety and physical discomfort. Other users suggested avoiding the treatment due to similar side effects and recommended alternative treatments like pyri.

      community Creatine and ru-58841 experiences?

      in Chat  1 upvotes 7 months ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community Azelaic acid with ru58841 combination

      in Treatment 2 months ago
      The conversation discusses using azelaic acid to reduce scalp inflammation while using RU58841 for hair loss. It suggests applying azelaic acid in the morning and RU58841 at night to avoid degradation, while also using dutasteride and minoxidil.

      community Pyrilutamide or RU or cb-03-01?

      in Minoxidil  2 upvotes 4 months ago
      The conversation discusses using Minoxidil, finasteride, RU58841, and pyrilutamide for hair loss treatment. The user is considering adding a topical treatment and has not experienced side effects from current treatments.

      community Oral Minoxidil and Grapefruit Juice

      in Research/Science  96 upvotes 2 years ago
      The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

      community How good is Minoxidil mixed with tretinoin

      in Minoxidil  3 upvotes 1 year ago
      Minoxidil combined with tretinoin may improve hair regrowth due to their synergistic effects. Using a gel with 0.025% tretinoin and antibiotics might still be beneficial.

      community discouraged about pyrilutamide

      in Research/Science  11 upvotes 3 years ago
      Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  132 upvotes 1 year ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Conceived on low dose topical fin (.025%), anyone else?

      in Finasteride/Dutasteride  6 upvotes 1 month ago
      A user expressed concern about using low-dose topical finasteride while conceiving, but was reassured that the risk of affecting a fetus is negligible. The user stopped using finasteride during pregnancy and switched to minoxidil and ketoconazole, while others shared experiences and advice on using these treatments safely.

      community Anyone know cheapest/best way to source RU58841 for Aussies?

      in Product  2 upvotes 1 month ago
      The conversation is about sourcing RU58841 for hair loss treatment in Australia and discusses the lack of effective alternatives. Alternatives mentioned include Kx826, fluridil, cb, alfatradiol, and topical spiro, but they are considered weak compared to RU58841.