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      community DHT is about to get smashed ….

      in Update  805 upvotes 1 year ago
      The conversation discusses hair loss treatments like topical finasteride with minoxidil, oral dutasteride, and essential oils. Oral treatments like dutasteride and finasteride are seen as more effective, though some prefer topicals to avoid side effects.

      community About to throw in towel. I just don't know anymore

      in Treatment  9 upvotes 11 months ago
      The user is experiencing severe side effects from finasteride, including sleep issues, depression, and gynecomastia, and is considering stopping the medication. They are exploring other treatments like RU58841 and dutasteride but are hesitant due to potential side effects.

      community Is it okay if I try ashwagandha?

      in Chat  13 upvotes 2 years ago
      The conversation discusses the potential effects of ashwagandha on hair loss and anxiety, with users sharing mixed experiences. Some users caution against ashwagandha due to its potential to increase testosterone and DHT, which could counteract finasteride's benefits, while others suggest alternative methods like exercise, cold showers, or different supplements for managing anxiety.

      community Oral minoxidil kullanan var mi?

      in General  122 upvotes 5 months ago
      The conversation is about finding a reliable source for oral minoxidil in Turkey, preferably in original packaging, and concerns about the safety and effectiveness of local products. The user is seeking recommendations for trustworthy suppliers and is wary of counterfeit products and scams.

      community Changing from topical to oral minoxidil

      in Minoxidil  2 upvotes 11 months ago
      A 22-year-old male is switching from topical to oral minoxidil due to limited results with topical use, while continuing oral finasteride and considering side effects. Users discuss experiences with oral minoxidil, noting potential side effects like swelling and headaches, but also its effectiveness compared to topical treatments.

      community 21M in Egypt Seeking Oral Minox Alternatives Due to Safety Concerns with Cat

      in Treatments  371 upvotes 4 months ago
      A user in Egypt is seeking alternatives to oral minoxidil, which is banned there, after stopping topical minoxidil due to concerns for their cat's safety. Suggestions include drinking diluted topical minoxidil or making homemade minoxidil tablets, but these methods carry significant risks and are not recommended.

      community If dutesteride and oral minoxidil doesn’t work that’s it right?

      in Treatment  41 upvotes 2 years ago
      A user is experiencing ongoing hair loss despite using 0.5mg dutasteride and 2.5mg oral minoxidil for several years and is seeking advice. Suggestions include ensuring correct diagnosis, checking for other health issues, considering finasteride, trying topical antiandrogens, and consulting a dermatologist.

      community Diy dutesteride please help MCT oil or PG?

      in Finasteride/Dutasteride  1 upvotes 5 months ago
      A user is making their own dutasteride solution using MCT oil but is concerned about its effectiveness and bioavailability. They are considering using propylene glycol or adding ethanol for better results, while others suggest the current dosage might be excessive.

      community Combining topicals together or use them separately

      in Chat  4 upvotes 7 months ago
      Combining Minoxidil with Finasteride or RU58841 may cause interference, irritation, or reduced absorption. It might be better to apply one topical at a time and wait an hour before applying another.

      community Thoughts on Hims Fin+Min all in one chews

      in Finasteride/Dutasteride  197 upvotes 2 years ago
      Users discussed the convenience and effectiveness of Hims Fin+Min chewable tablets for hair loss. Some believe it's overpriced compared to traditional oral finasteride and minoxidil, while others find it more convenient and potentially more effective.

      community Potassium and oral min need each other??

      in Minoxidil  4 upvotes 1 year ago
      Oral minoxidil may require potassium for effectiveness, and diuretics taken for water retention might affect this process. The user plans to start taking potassium to address potential issues with minoxidil's effectiveness.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Finally live! alcohol-free, propylene glycol–free topical finasteride foam

      in Update  18 upvotes 5 months ago
      A new alcohol-free, propylene glycol-free topical finasteride foam is available for prescription in Canada and the USA, offering a cleaner alternative for hair loss treatment. The product also offers a combination of 0.1% finasteride with 5% minoxidil and aims to be affordable and less irritating for sensitive scalps.

      community Progress finasteride and minoxidil + problem

      in Progress Pictures  2 upvotes 1 year ago
      The user is experiencing hair improvement in the central and back areas after using finasteride, minoxidil, and a galenic lotion, but the temple area is worsening. They suspect the lotion might be causing the issue and are considering stopping its use.

      community Topical Minoxodil vs Oral Minoxodil

      in Minoxidil  92 upvotes 1 year ago
      A user has been using topical minoxidil and finasteride for hair loss but is considering switching to oral minoxidil due to the inconvenience of topical application. Another user cautions that switching forms may cause shedding and that oral minoxidil may have different side effects and results.

      community Should i wait for breezula while taking topical

      in Chat  2 upvotes 3 months ago
      The conversation discusses whether to wait for Breezula while using topical minoxidil to avoid side effects from finasteride. It mentions Breezula's potential release in a year and its cost and long-term use considerations.

      community Which retinoid for better min absorption?

      in Product  4 upvotes 1 year ago
      User is on vacation in Greece and wants to buy tretinoin or isotretinoin to improve Minoxidil absorption. They are considering isotretinoin since it is available over-the-counter in Greece but requires a prescription back home.

      community Why not just take the drugs before hair loss?

      in Chat  123 upvotes 2 months ago
      Finasteride and dutasteride are discussed as preventative treatments for hair loss, with some advocating for early use and others concerned about side effects, especially before full maturity. Many regret not starting these treatments earlier due to their effectiveness in preventing or slowing hair loss.

      community Topical solution recommendation

      in Treatment  2 upvotes 9 months ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.
      Any experiences with fin/dut alternatives?

      community Any experiences with fin/dut alternatives?

      in General  76 upvotes 10 months ago
      The user is exploring alternatives to finasteride and dutasteride due to concerns about side effects, and is using rosemary and jojoba oil, ketoconazole, minoxidil, microneedling, multi-peptide serum, saw palmetto, and stinging nettle for hair loss. They are also considering CB 03 01 and spironolactone.

      community RU58841 mixing with water solution

      in Research/Science  4 upvotes 4 years ago
      RU58841 is being mixed with Minoxidil solution, but concerns arise about water causing instability. Mixing with water may lead to hydrolysis, potentially reducing effectiveness.