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      community Ru-58841 or KX-826 (Pyrilutamide)?

      in Treatment  13 upvotes 3 years ago
      Exploring potential treatments for hair loss, with the focus being on comparing RU58841 and Pyrilutamide. Finasteride, Dutasteride, oral Minoxidil, microneedling, topical Minoxidil, Biotin, Zinc, Vitamin D and Nizoral are also discussed as part of a treatment stack.

      community Help! Minoxidil or Duta to avoid Shed of long hair.

      in Female  7 upvotes 1 year ago
      The user is considering using Tacrolimus Solution and topical Dutasteride to avoid shedding caused by Minoxidil, which they fear may lead to facial side effects. They are also concerned about scalp sensitivity and are exploring different treatment bases to manage seborrheic dermatitis.

      community Any alternatives to topical min?

      in Treatment  1 upvotes 9 months ago
      The user is considering alternatives to topical minoxidil for hair growth due to concerns about future cat ownership, mentioning stemoxydine and redensyl as possibilities. They currently use topical regaine foam and oral finasteride.

      community 8 months Fin and Min. Now on stronger regiment

      in Progress Pictures  7 upvotes 1 year ago
      The user shared progress pictures after 10 months of hair loss treatment, initially using 1mg Finasteride and 5mg Minoxidil, then switching to 2.5mg Minoxidil, topical Minoxidil, and RU58841. Recently, they added 0.5mg Dutasteride to their regimen.

      community 8 months of 0.5 mg dut daily, 14 months of 5 mg oral min

      in Progress Pictures  3 upvotes 2 weeks ago
      The user has been using 0.5 mg dutasteride daily for 8 months and 5 mg oral minoxidil for 14 months to address hair thinning. Despite some users seeing no change or improvement, the user feels their hairline density has decreased and corners have worsened.

      community ZeroMino Product Minoxidilmax?

      in Product  1 upvotes 2 years ago
      New product on minoxidilmax contains adenosine, caffeine, niacinamide, melatonin, azelaic acid, and biotin. User asks if it works for hair loss.

      community Creatine is the opposite of minoxidil !

      in Research/Science  321 upvotes 5 months ago
      Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 1 year ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community New approach: oral and topical min

      in Progress Pictures 1 year ago
      The user is trying a new hair loss treatment combining 1.25 mg oral minoxidil with a daily topical solution containing hydrocortisone, tretinoin, 8% minoxidil, and 0.025% finasteride. They aim to maintain their current hair before considering a hair transplant in Istanbul.

      community 6 months on min-fin medication

      in Progress Pictures  610 upvotes 6 months ago
      A 42-year-old user shared progress after 6 months using 1.25mg finasteride and 5mg oral minoxidil daily, with 5% topical minoxidil twice a day, improved nutrition, and weekly dermarolling. The user noticed some shedding and slower regrowth but remains disciplined, while others commented on the impressive results and potential side effects of high minoxidil doses.

      community Finasteyd topical 0.025% minoxidil and caffeine action

      in Progress Pictures  102 upvotes 1 year ago
      The user "OP" uses a combination of topical minoxidil 5%, finasteride 0.025%, and caffeine to combat hair loss, with noticeable results over 5-6 months. Side effects include unwanted body hair growth and an itchy scalp, but no significant sexual side effects.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  63 upvotes 2 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community The mechanism of androgenic alopecia

      in Research/Science  34 upvotes 6 months ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community How effective would this be compared to just topical min + fin?

      in Finasteride  4 upvotes 6 years ago
      The user discusses using a topical solution with minoxidil, finasteride, and additional ingredients like apigenin, oleanolic acid, and biotinoyl tripeptide. They question if this combination is more effective than using just minoxidil and finasteride alone, noting they are already taking oral finasteride.

      community Oral minoxidil hypertension after stopping

      in General  48 upvotes 4 months ago
      The user switched from topical to oral minoxidil (5mg daily) a year ago, saw no improvement, and experienced chest pain and trouble sleeping after stopping. They are considering whether to resume and taper the dosage due to stress and anxiety.

      community RU58841 or topical spironolactone??

      in Research/Science  2 upvotes 4 years ago
      The conversation is about choosing between RU58841 and topical spironolactone for hair loss treatment. The user is currently using a topical solution with minoxidil, alfatradiol, and progesterone, and is concerned about side effects and effectiveness of both RU58841 and spironolactone.

      community What happens if you combine dutasteride and a aromataze inhibitor?

      in Question  4 upvotes 6 years ago
      Combining dutasteride and an aromatase inhibitor may increase testosterone levels significantly, potentially enhancing athletic performance but also posing health risks like elevated blood pressure and worsened cholesterol. The user is experimenting with dutasteride, anastrozole, minoxidil, and ketoconazole shampoo to manage hair loss and estradiol levels, while monitoring side effects and hormone levels.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  124 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Minoxidil 5% with 0.01% tretinoin

      in Treatment  1 upvotes 1 year ago
      Minoxidil 5% combined with 0.01% tretinoin may be as effective as using minoxidil twice daily. Users discuss switching to oral minoxidil for consistency, with concerns about side effects.

      community Dutasteride + oral min progress

      in Progress Pictures  537 upvotes 1 year ago
      A 20-year-old used finasteride for 5 months, then switched to dutasteride for 7 months, and added oral minoxidil for 2.5 months, finding the combination of dutasteride and oral minoxidil most effective. The user experienced significant hair improvement and confidence boost, with no blood tests but an ECG to monitor heart health.