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      community Curious about 'nuclear' stacks

      in Research/Science  1 upvotes 1 year ago
      The conversation discusses using higher doses of minoxidil and finasteride, considering dutasteride, and exploring other treatments like RU58841 for hair preservation. The user reports no side effects after six months and is interested in advanced treatment combinations.

      community Thoughts on Pantostin Alfatradiol?

      in Treatment  10 upvotes 4 years ago
      User started using Pantostin Alfatradiol after watching haircafe on YouTube and noticed thicker hair. They wonder why it's not more popular, as it's a 5α-reductase inhibitor with a different mechanism than minoxidil.

      community MSM Supplementation is helping my hairs

      in Update  3 upvotes 1 month ago
      The user reports that MSM supplementation has thickened their hair strands while using finasteride and topical minoxidil. They also take zinc, copper, B-complex, vitamin C, vitamin D3, and K2, and plan to add omega-3, magnesium, astaxanthin, and pterostilbene.

      community Any treatment not nuking systemic DHT levels?

      in Finasteride/Dutasteride  17 upvotes 1 month ago
      Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 2 years ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community What's the deal with Spectral.DNC-N/'nanoxidil'?

      in Minoxidil  5 upvotes 3 years ago
      Nanoxidil is considered to have better absorption and fewer side effects than minoxidil, with added DHT blockers. The user is questioning if switching to the more expensive Spectral.DNC-N is worthwhile compared to cheaper options like Kirkland minoxidil.

      community what do you think about Ell-Cranell + Quercetin

      in Treatment  7 upvotes 2 years ago
      The post discusses the use of El-Cranell, which contains Alfatradiol, and Quercetin as a treatment for hair loss. The user is seeking recommendations on the amount of Quercetin to add to the solution. The conclusion of the document is that Quercetin has been shown to stimulate hair growth and inhibit DHT, and combining it with zinc/copper may have a synergistic effect.

      community Redness and flaking from topical minoxidil

      in Minoxidil  2 upvotes 1 year ago
      Topical minoxidil with tretinoin is causing redness, stinging, and flaking on the scalp. Reducing application frequency and using anti-dandruff shampoo may help alleviate symptoms over time.

      community Anyone knows if koshine kx-826 has propylene glicol?

      in Product 6 months ago
      Koshine KX-826 has different versions, and the green version uses a plant-based carrier that may be less irritating for those sensitive to propylene glycol. Users report irritation with some versions of KX-826.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  5 upvotes 1 year ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Tretinoin, any good, what’s your experience

      in Research/Science  21 upvotes 1 year ago
      The conversation discusses using tretinoin for hair loss and skincare. Users share experiences, noting tretinoin's effectiveness in combination with minoxidil for hair and its proven benefits for anti-aging skincare.

      community 2-Deoxy-D-Ribose official Product

      in Research/Science  5 upvotes 1 year ago
      2-Deoxy-D-Ribose is discussed as a potential hair loss treatment, but skepticism exists due to lack of human testing. The original poster uses a combination of topical Minoxidil, oral Finasteride, topical RU58841, and other treatments, reporting some hair regrowth but not significant results.

      community Drastic loss after stabilization for 5 years of DHT blockers, topical minoxidil, nizoral shampoo

      in Update  8 upvotes 1 year ago
      A 27-year-old is experiencing significant hair loss despite using a combination of 0.5mg dutasteride daily, topical minoxidil, nizoral shampoo, and vitamin D optimization, and is now starting zinc supplementation. Suggestions include considering other causes, possibly increasing dutasteride dosage, switching to oral minoxidil, or maintaining the current regimen and reassessing in six months.

      community Any proof backing Nanoxidil over Minoxidil?

      in Minoxidil  4 upvotes 2 years ago
      The conversation discusses hair loss treatments, specifically comparing Nanoxidil and Minoxidil. The user reports no benefits from either treatment and expresses concern about micro-needling worsening their condition.

      community Have any of you given Nanoxidil a try?

      in Product  4 upvotes 3 years ago
      Nanoxidil is discussed as a potential alternative to Minoxidil for hair loss, with some users reporting better results and improved hair strength. However, concerns about its lack of FDA approval and potential scalp dryness are noted.

      community Effect of melatonin on aromatase expression

      in Update  4 upvotes 3 years ago
      Melatonin's effect on aromatase expression is unclear, with studies showing both increases and decreases. Hormonal impacts are complex and inconsistent, similar to changing health advice on other substances.