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      community Any advice on getting dht blockers in prison?

      in Chat  31 upvotes 10 months ago
      A person in prison is seeking advice on maintaining hair with treatments like Minoxidil and dutasteride, and others suggest options like Propecia, HRT, or going bald. The conversation includes jokes and serious concerns about the challenges of accessing hair loss treatments in prison.

      community waiting for hope DIY pp405 guy that will save usπŸ˜‘πŸ˜‘πŸ˜”

      in Satire  38 upvotes 7 months ago
      People are discussing the potential of a new hair loss treatment, pp405, and its approval timeline, comparing it to existing treatments like Minoxidil and finasteride. There is skepticism about its effectiveness and concerns about the time it will take for approval and availability, especially in Europe.

      community Which to pill to try. Advice please!

      in Treatment  3 upvotes 5 months ago
      The conversation is about hair loss treatments, specifically discussing the use of minoxidil, finasteride, and dutasteride. The advice suggests continuing minoxidil and considering dutasteride or finasteride as DHT blockers, with a focus on managing potential shedding and side effects.

      community EU topical melatonin recommendations?

      in Treatment  6 upvotes 5 months ago
      The conversation discusses recommendations for using topical melatonin for hair loss treatment. It also mentions Minoxidil, finasteride, and RU58841 as other treatments.

      community Pp405 full presentation on new topical

      in Product  105 upvotes 3 months ago
      A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.

      community Dealing with Retrograde Alopecia

      in Treatment  6 upvotes 4 years ago
      User on Dut, oral minox 20 mg, Saw Palmetto, Pumpkin Oil, RU, 8% topical minox, and topical fina for hair loss; top of head improves, but retrograde alopecia worsens. Asks for options besides exosomes and where to find topical melatonin.

      community Pyrilutamide US Phase 2 Trial?

      in Research/Science  27 upvotes 3 years ago
      The Phase 2 trial for Pyrilutamide in the US, which started a year after the China trials, and inquiring about any available information on when it will finish. Treatments discussed include Minoxidil, Finasteride, and RU58841.

      community treatment of Bicalutamide low dose weekly?

      in Treatment  5 upvotes 4 years ago
      The conversation is about using bicalutamide, taken less frequently than daily, for hair loss treatment. The user is considering 50mg every 3 days or once a week and is asking for others' experiences.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 6 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community Are any of you using topical spironolactone ?

      in Treatment  4 upvotes 10 months ago
      The user is using topical dutasteride, minoxidil, and spironolactone for hair loss, with positive results after adding spironolactone. Another user takes oral spironolactone, dutasteride, and finasteride, noting decreased libido but no major side effects.

      community Is PP405 actually different, or does it fall into the same pattern as previous treatments?

      in Research/Science 3 months ago
      PP405 is being discussed as a potential new approach to hair loss by targeting follicle stem cells, suggesting a different mechanism from existing treatments like finasteride and minoxidil. However, there is skepticism about whether it will lead to meaningful long-term outcomes or follow the pattern of previous treatments that showed promise but lacked consistent results.

      community Fin 1 mg oral 1x/day + min topical 2x/day, 4 months progress

      in Progress Pictures 3 years ago
      Anxious_Bee_67's 4 month progress with a hair loss treatment regimen of 1 mg oral finasteride once a day and topical minoxidil twice a day, which has brought "hope" to others who are fighting the Norwood Reaper. Replies include encouragement for further progress and advice on other treatments that can be used in conjunction with the current ones.
      Should I start treatment or am I cooked?

      community Should I start treatment or am I cooked?

      in General  78 upvotes 1 year ago
      The user is concerned about hair loss and wonders if it could be due to product use or stress, despite having family members with full hair. They are considering starting treatment with Minoxidil, finasteride, or RU58841.

      community Pp405 phase 2a clinical results

      in Research/Science  40 upvotes 1 year ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community Bicalutamide vs Finasteride for female AGA plus TE

      in Female  3 upvotes 4 months ago
      OP is considering Bicalutamide for female AGA and TE but is concerned about its side effects and effectiveness compared to Finasteride. OP is also using Minoxidil and Spironolactone but is experiencing significant shedding and is unsure if it's androgen-driven or due to Minoxidil changes.

      community Complete non responder to everything. Modern Norwood Sisyphus

      in Update  76 upvotes 1 year ago
      The user has been using finasteride for four years and topical minoxidil with microneedling for a year but has not seen significant results in slowing hair loss. They are considering trying dutasteride despite concerns about its intensity, and others suggest trying oral minoxidil or combining treatments for better results.

      community Female male-pattern AGA- seeking help

      in Female  1 upvotes 2 years ago
      A female with male-pattern hair loss (AGA) is seeking help after unsuccessful treatments with spironolactone and supplements, and is considering oral minoxidil and finasteride despite concerns about medication side effects. She has ruled out hormonal birth control and PRP/PRFM, and is looking into further medical advice due to abnormal lab results.

      community Stop Lurking and Start Treatment NOW

      in Chat  62 upvotes 4 years ago
      Start hair loss treatment as soon as you notice thinning to prevent further loss; finasteride and minoxidil are suggested treatments, with the option to switch to topical treatments if side effects occur. Some regret not starting treatment earlier, and maintaining current hair is more likely than regrowth.

      community Why is there so much negativity around pyrilutamide?

      in Research/Science  19 upvotes 1 year ago
      Pyrilutamide is discussed as an effective hair loss treatment by some users, despite skepticism due to limited data and underwhelming trial results. Users compare it to finasteride, minoxidil, and RU58841, with some expressing interest in its potential as an adjunct treatment.

      community Solution for male pattern baldness

      in Treatment  241 upvotes 6 months ago
      A new hair loss treatment claims a 539% improvement over placebo, but skepticism remains due to lack of substantial evidence and reliance on percentage figures. Users discuss the effectiveness of existing treatments like Minoxidil and Finasteride, expressing doubt about the new solution's impact.

      community Need motivation, can’t live normally

      in Treatment  9 upvotes 1 year ago
      A 20-year-old experiencing hair thinning became depressed and sought treatment. The new dermatologist prescribed a routine including topical minoxidil, finasteride, derma stamping, Nizoral shampoo, rosemary oil, and scalp massages.

      community Does everything that reduces DHT block 5ar?

      in Treatment  46 upvotes 2 years ago
      Finasteride is the most effective treatment for reducing DHT and addressing hair loss compared to fish oil and saw palmetto. Topical treatments like RU58841 and minoxidil are also discussed, but finasteride remains the most effective option.