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      community The Big Fat Layer II

      in Research/Science  26 upvotes 5 years ago
      Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

      community 7.5 months and fin, time for dut?

      in Finasteride/Dutasteride  12 upvotes 2 years ago
      The user has been using 1mg finasteride, 2% ketoconazole shampoo, vitamins, and growth shampoo for 7.5 months to treat hair loss and is considering switching to 0.5 mg dutasteride due to slight recession and persistent symptoms. Another user commented that the user's temples appear to have improved, especially in the latest photo.

      community Alfatradiol Experience (2 months)

      in Treatment  12 upvotes 5 years ago
      User experienced side effects from oral finasteride and tried topical Alfatradiol for hair loss. Alfatradiol provided maintenance without significant regrowth, and user suggests it as an alternative for those struggling with finasteride side effects.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community Finasteride, minoxidil and pyrilutamide

      in Progress Pictures  79 upvotes 2 years ago
      The user tried minoxidil 5% for 3 years with little improvement, then switched to a 15% minoxidil with 0.1% finasteride solution once daily and started using pyrilutamide, resulting in significant hair regrowth over time. They are considering a hair transplant but are continuing with topical treatments to maximize hair growth first.

      community We need actual hair loss studies on Epristeride

      in Research/Science  6 upvotes 1 year ago
      Epristeride is a selective 5 alpha reductase type 2 inhibitor that may reduce scalp DHT similarly to finasteride, with potentially fewer side effects. It is suggested that combining epristeride with finasteride or dutasteride could enhance hair loss treatment effectiveness.

      community Rate my Hair loss prevention stack

      in Treatment  5 upvotes 3 months ago
      The user is using a comprehensive hair loss prevention regimen including Dutasteride, RU58841, topical treatments, red light therapy, microneedling, and supplements like Nutrafol, while avoiding Minoxidil. They also supplement with vitamin D and zinc and plan to start testosterone replacement therapy (TRT) in January.

      community Bad reaction to Finasteride, what are my other options?

      in Transplants  15 upvotes 3 years ago
      A user had a bad reaction to Finasteride, experiencing anxiety and fatigue, and is seeking alternative hair loss treatments since they can't use Finasteride or Minoxidil. Suggestions include trying low doses of Finasteride, making a topical version, or using other treatments like Alfatradiol, but the user is hesitant to use Finasteride again and is considering a hair transplant.

      community Take licorice to lower testosterone?

      in Question  1 upvotes 9 years ago
      Licorice is not recommended for hair loss as it inhibits hair growth and is a non-selective testosterone inhibitor. Alternatives like spironolactone are suggested for those considering hormonal treatments for hair loss.

      community Duoxidil, Dutasteride and oral Minoxidil

      in Minoxidil  89 upvotes 6 months ago
      The conversation discusses hair regrowth treatments, specifically using a combination of oral and topical minoxidil, oral and topical dutasteride, and PRP. There is skepticism about the authenticity of the results, with some users questioning the changes in hair and skin appearance.

      community Thoughts on new drug PP405? Already reached phase 2

      in Research/Science  28 upvotes 10 months ago
      PP405 is a new drug in Phase 2 trials for hair loss, generating cautious optimism among users. Some users are currently using finasteride and experiencing side effects, while others are skeptical about unapproved products being sold.

      community Oral minoxidyl and topical minoxidyl

      in Minoxidil  2 upvotes 1 year ago
      Using both oral and topical minoxidil is likely safe, but be cautious of increased systemic absorption. The best tretinoin dosage to enhance minoxidil effectiveness is not specified.

      community Been on Dut for 2 1/2 years. AMA

      in Finasteride/Dutasteride  20 upvotes 4 months ago
      The user shares a positive experience with Dutasteride for hair loss, noting increased hair density and minimal side effects after switching from Finasteride. They prefer oral Dutasteride and avoid Minoxidil due to its inconvenience and potential risks.

      community Any male on topical spironolactone?

      in Research/Science  7 upvotes 3 months ago
      Topical spironolactone is discussed for hair loss treatment, with mentions of DIY solutions and dermatologist compounding. Users inquire about regrowth and sourcing the treatment.

      community The most nuclear stack possible

      in Satire  41 upvotes 1 year ago
      A user humorously suggests an extreme hair loss treatment regimen involving multiple medications and therapies, including Dutasteride, Minoxidil, RU58841, and others, claiming it would prevent hair loss but with potential side effects like gynecomastia. The conversation highlights concerns about safety, side effects, and the effectiveness of such a comprehensive approach.

      community Trichotest Results: no Finasteride

      in Finasteride/Dutasteride  5 upvotes 3 years ago
      The user received trichotest results indicating finasteride is ineffective for them, and they plan to use dutasteride mesotherapy and add cetirizine to minoxidil. They seek advice on incorporating dutasteride into their regimen.

      community 1 year daily dut progress 0.5mg

      in Progress Pictures  43 upvotes 10 months ago
      The user has been using 0.5mg daily dutasteride for a year without seeing progress and previously used oral finasteride and topical minoxidil. They are considering a hair transplant and discussing various treatments like scalp massages, derma rolling, and different medication dosages.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 2 years ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community M29 Dut/Min/Microneedle/Tretinoin

      in Is this regrowth?  24 upvotes 1 year ago
      A user has been using finasteride since 2018, switched to dutasteride, and added minoxidil, microneedling, and a tretinoin/spiro compound. They are pleased with the results and hopeful for more improvement.
      TresslessGPT is now available for free

      community TresslessGPT is now available for free

      in General  386 upvotes 1 year ago
      Tressless GPT is now free and accessible for hair loss advice. Treatments discussed include Minoxidil, finasteride, RU58841, dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

      community HairCafe was right about trolls on dutasteride

      in Chat  232 upvotes 1 year ago
      A user falsely claimed to use 2.5mg of dutasteride by using someone else's photo, which actually showed results from finasteride. The conversation discusses the challenges and skepticism around hair loss treatments like dutasteride and finasteride.