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      community New Hair Loss Treatment: Adipose Derived Secretomes

      in Research/Science  17 upvotes 11 months ago
      Adipose-derived stem cell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.

      community Mix Pyrilutamide powder in Minoxidil solution?

      in Minoxidil  3 upvotes 2 years ago
      Mixing Pyrilutamide powder with Minoxidil solution is being considered. The Minoxidil solution contains Minoxidil 5%, Azelaic acid 5%, ABN complex 0.8%, Retinol 0.025%, Caffeine 0.001%, and a delivery vehicle.

      community A concern regarding the upcoming androgen degrader drug GT20029

      in Chat  12 upvotes 1 year ago
      GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

      community Is S5 plus cream an okay alternative to finasteride?

      in Finasteride  4 upvotes 9 years ago
      The conversation discusses using S5 plus cream (Spironolactone, Alfatradiol, and Tempol) as an alternative to finasteride for hair loss, with concerns about its effectiveness and potential systemic absorption. The original poster already uses 5% minoxidil and is seeking alternatives due to fears of finasteride's side effects.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

      in Chat  13 upvotes 4 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community Thoughts on these and similar other products?

      in Chat  4 upvotes 1 year ago
      The conversation discusses the effectiveness of DHT blockers for hair loss, questioning if they are just vitamins or truly effective. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Positive Hair Result in Patient using Tirzepatide

      in Research/Science  6 upvotes 1 year ago
      A 57-year-old man with male pattern hair loss and insulin resistance experienced hair regrowth and weight loss after using tirzepatide, without other hair treatments. Dysregulated glucose metabolism is linked to hair loss, with tirzepatide potentially improving hair density by normalizing insulin resistance.
      Sudden Triangular Thinning Patch

      community Sudden Triangular Thinning Patch

      in General  157 upvotes 7 months ago
      A 31-year-old has been using finasteride, dutasteride, and oral minoxidil for hair loss. They noticed a sudden triangular thinning patch on their scalp and are seeking advice, questioning if it could be medication-related.

      community applying tretinoin and SPF on scalp?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses using tretinoin for hair loss and whether applying SPF on the scalp is necessary if hair covers the treated areas. The user is considering this treatment despite having no completely bald patches.

      community Setipiprant trial results

      in Update  13 upvotes 7 years ago
      Setipiprant trial for hair loss failed, showing no difference between placebo and treatment. Discussion also noted placebo users reporting side effects.

      community Lyphar Biotech. China source for RU58841

      in Research/Science  1 upvotes 1 month ago
      The conversation discusses the safety and trustworthiness of ordering RU58841 from Lyphar Biotech in China, with a focus on pricing and reliability. The user is seeking advice on whether to proceed with the purchase or consider alternative sources.

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI

      in Finasteride/Dutasteride  26 upvotes 1 year ago
      The conversation discusses the effectiveness and skepticism around topical dutasteride for hair loss, with mentions of combining it with other treatments like minoxidil and oral medications. Some users doubt its efficacy due to lack of independent studies and potential conflicts of interest.

      community Thoughts on my Topical and Oral concept idea ?

      in Treatment  1 upvotes 1 year ago
      The user is seeking advice on improving their hair loss treatment regimen, considering changes to their topical solution, and is curious about others' daily routines and recommendations for medications and supplements. They are contemplating switching Tretinoin for Tazarotene, Latanoprost for Bimatoprost, and possibly adding Alfatradiol, Topical Melatonin, or a topical androgen receptor antagonist.

      community Topical Serenoa? Anyone tried it?

      in Treatment  2 upvotes 1 month ago
      The conversation discusses using topical serenoa oil, a natural anti-DHT treatment, for hair loss. It is considered less effective than finasteride and dutasteride but can be added to a routine with topical minoxidil.

      community Fuck it, I’m ordering Pyri Topical

      in Product  12 upvotes 1 year ago
      A user plans to order Pyrilutamide for hair loss after losing ground on finasteride. Another user advises against buying from Hairliciously, suggesting Amazon instead.

      community Does pyrilutamide actually work?

      in Treatment  24 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment, and how it compares to existing treatments such as Minoxidil, Finasteride and RU58841. Real-world results are being discussed to determine its effectiveness.

      community Topical solution recommendation

      in Treatment  2 upvotes 8 months ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community Clascoterone - what we have right now

      in Research/Science  19 upvotes 1 month ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.