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      community Pyrilutamide is literally my only hope

      in Chat  91 upvotes 3 years ago
      Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.

      community Breezula Phase 3 confusion - did they change something?

      in Chat  10 upvotes 6 months ago
      Breezula's phase 2 showed reduced efficacy after 6 months, but phase 3 had positive results, causing confusion about any changes made to the drug. There is frustration over the long timeline for hair loss treatments, with some users expressing more interest in other potential treatments like GT-20029.

      community Hair follicle cloning is already possible

      in Chat  38 upvotes 1 year ago
      Hair follicle cloning is claimed to be possible but not widely available due to potential safety issues, such as cancer risks. Current treatments like finasteride and dutasteride are not effective for everyone, and there is frustration over limited access to these medications.

      community Switching to Dutasteride Foam During Norwood 2 Shedding Phase

      in General  70 upvotes 8 months ago
      The user is considering switching from Minoxidil to dutasteride for hair loss treatment but is concerned about the potential for increased shedding. They are seeking advice on whether to wait for the current shedding phase to subside before starting dutasteride.

      community Chances GT20029 releases by 2028?

      in Technology  7 upvotes 3 years ago
      The conversation is about hair loss treatments, specifically the anticipation for the release of a new treatment, GT20029, by 2028. Users are discussing their experiences with current treatments like finasteride and dutasteride, and the potential of future treatments, including FAK inhibitors and verteporfin trials.

      community I guess I’m cooked. 1mg fin/day 2.5 mg min/day + topical tretinoin (3x/week) + topical min/day. June 2023-june 2025

      in Progress Pictures  2 upvotes 1 year ago
      The user has been using 1mg finasteride daily, 2.5mg minoxidil daily, topical tretinoin three times a week, and topical minoxidil daily from June 2023 to June 2025 without noticeable improvement in hair loss. Suggestions include switching to dutasteride and increasing oral minoxidil to 5mg daily, but concerns about long-term health effects are raised.

      community Hair theory Scar tissue and Verteporfin

      in Chat  25 upvotes 2 years ago
      A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.

      community Update progress on Fin, Min, and Kx-826

      in Is this regrowth?  7 upvotes 1 year ago
      The user is using oral finasteride, minoxidil, and KX-826 for hair regrowth, noticing small improvements. They plan to add ketoconazole shampoo and consider a hair transplant with verteporfin after a year of treatment.

      community Hair follicle neogenesis

       7 upvotes 11 years ago
      A user plans to experiment with creating new hair follicles using methods like derma rolling, applying lithium chloride, tannic acid, and various other substances including caffeine, ketoconazole, and raspberry ketones. They also consider using anti-inflammatories, immunosuppressants, and DHT inhibitors to potentially improve results.

      community I Get Side-Effects from Anti-Androgens

      in Finasteride/Dutasteride  8 upvotes 5 years ago
      Someone looking for solutions to their hair loss, who has tried and failed to tolerate anti-androgen treatments such as finasteride, CB-03-01, RU58841, and Eucapil. The user is seeking advice and understanding of their extreme sensitivity to these treatments.

      community Help! Minoxidil or Duta to avoid Shed of long hair.

      in Female  8 upvotes 1 year ago
      The user is considering using Tacrolimus Solution and topical Dutasteride to avoid shedding caused by Minoxidil, which they fear may lead to facial side effects. They are also concerned about scalp sensitivity and are exploring different treatment bases to manage seborrheic dermatitis.

      community IGF-1 and Peptides? Miracle molecule waiting to be found

      in Research/Science  10 upvotes 10 months ago
      The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

      community P5P supplementation for fin sides.

      in Treatment  7 upvotes 4 years ago
      P5P supplementation helped reverse finasteride side effects, particularly by lowering prolactin levels and restoring sensitivity. The user experienced significant improvement within a day and full recovery in a few days.

      community Adapalene gel 1% cause of hair loss?

      in Treatment  4 upvotes 3 years ago
      A user experienced hair thinning after using Adapalene gel 1% for skin care, suspecting it contributed to hair loss alongside depression and anxiety. They stopped using Adapalene and switched to a Minoxidil/Finasteride formula, noticing hair improvement, while others in the conversation doubted Adapalene's impact on hair loss.

      community Washing hair every day instead of a couple times a week

      in Treatment  7 upvotes 5 years ago
      The user discusses the potential impact of external DHT in sebum on hair loss and plans to wash their hair daily with salicylic acid exfoliation. They believe this might help reduce hair loss despite internal factors.

      community HT booked, taking finasteride and losing ground?

      in I'm Starting Treatment  1 upvotes 5 months ago
      The user is concerned about hair loss despite taking finasteride and has a hair transplant scheduled. They experience scalp itching and burning, which hasn't been relieved by various treatments, and another user suggests using ghk-cu & ahk-cu serum and Koshine kx-826/pyrilutamide for relief.

      community I wrote a poem about pp405 (potential treatment)

      in Satire  19 upvotes 1 year ago
      A poem humorously suggests hope for a new hair loss treatment, PP405, while users debate the effectiveness and side effects of current treatments like Finasteride. Concerns are raised about Finasteride's side effects, especially for young users, and skepticism about new treatments is expressed.

      community Topical Finasteride Users – When Did Your Shedding Stabilize? (DUPA Case)

      in Treatments  112 upvotes 11 months ago
      The user is using a self-made topical mix of finasteride and minoxidil foam for hair loss, experiencing solid regrowth in the frontal area and mild improvement at the crown, but still shedding. They previously used oral finasteride and dutasteride but stopped due to side effects, and are seeking advice on when shedding might stabilize with the topical treatment.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.