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community People are misunderstanding PP405. 31% response at 8 weeks is better than you think

in Research/Science 181 upvotes 1 year ago

PP405 shows promise as a hair loss treatment, with 31% experiencing increased hair density in a short trial. It may complement treatments like finasteride and minoxidil, but long-term effectiveness and safety need confirmation.

community Anyone have an alternative solvent for pyrilutamide??

in Product 2 upvotes 2 years ago

The user is seeking an alternative solvent for pyrilutamide due to skin irritation from ethanol and propylene glycol. They experienced similar issues with topical minoxidil.

community Chat Gpt approves ,my Current Regimen

in Treatment 2 years ago

The conversation is about a hair loss treatment regimen that does not include finasteride. Specific treatments used are not mentioned.

community It looks like Pelage are giving hints that PP405 is a game changer

in Chat 239 upvotes 4 months ago

PP405 is seen as a potential breakthrough for converting vellus hairs to terminal hairs, with users expressing both hope and skepticism. It is compared to treatments like minoxidil and finasteride, with discussions on side effects and marketing concerns.

community Federal Grant Cuts have impacted PP405 related research

in Technology 460 upvotes 11 months ago

Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

community RU58841 is the only thing that worked for me, a DUPA sufferer

in Treatment 1 upvotes 1 year ago

RU58841 was the only treatment that slowed hair loss and reduced irritation for a DUPA sufferer after trying finasteride, minoxidil, and dutasteride with no success. The user continues using 6mg oral minoxidil, 0.5mg dutasteride, and an 8% RU58841 solution.

community Feel like im not making process. Had insane shed. (Min/Fin/HRT)

in Progress Pictures 5 upvotes 3 months ago

The user started using oral minoxidil and estradiol in August 2025, added finasteride in December, and experienced significant hair shedding in February/March. They switched to estradiol injections and are considering their hair washing routine, while another user suggested consulting a dermatologist and possibly trying dutasteride.

community Who else is looking forward to full phase 2 results of PP405?

in Chat 59 upvotes 6 months ago

PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.

community Seriously considering Dut. (+ photos, my regime and QUESTIONS)

5 upvotes 10 years ago

A 23-year-old with hair loss uses finasteride, minoxidil, and other treatments, considering adding dutasteride due to hairline recession. They seek advice on dutasteride's effectiveness and sourcing.

community Reaching the End

in Update 7 upvotes 5 years ago

User tried dutasteride, topical finasteride, oral minox, dermawounding, saw palmetto, pumpkin seed oil, and ketacozonole for hair loss. Improvement was temporary, now trying RU58841 and seeking help.

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