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community 28M with Diffuse Thinning and Donor Area Affected, Dutasteride Not Working, Advice on Next Steps?
A 28-year-old male experiencing diffuse thinning and miniaturization around the ears and back has tried finasteride, dutasteride, and both topical and oral minoxidil without success. He is seeking advice on identifying the type of hair loss and next steps since current treatments are ineffective.
community Nice & pure PRP, 3 ml of this is going to the scalp.
The use of PRP to treat hair loss and its potential effectiveness when combined with 5 alpha reductase blockers such as Minoxidil or Finasteride.
community Microneedling with liposomal minoxidil
Microneedling may enhance the effectiveness of liposomal minoxidil for hair loss. The user is also using tretinoin.
community I ended up in the ER due to oral Minoxodil.
A user experienced severe side effects, including heart issues, after taking oral minoxidil without consulting a doctor. They are now considering alternatives like dutasteride, PRP, or laser treatments for hair loss.
community GT20029 Anageninc Market Availability
The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.
community Oral Minoxidil- Be Careful!!!!!
Oral minoxidil can cause severe side effects, including heart issues, even at low doses. Users suggest starting with a lower dose or using topical treatments to minimize risks.
community HLT Megathread on HMI-115 (key takeaways in comments)
HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
community Which Saw Palmetto is good for blocking 5 alpha reductase, Serenoa repens or Chamaerops humilis?
The conversation is about determining which type of Saw Palmetto, either Chamaerops humilis or Serenoa repens, is effective for inhibiting the 5 alpha reductase enzyme related to hair loss. Specific treatments mentioned are Minoxidil, finasteride, and RU58841.
community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?
Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.
community 10 month progress - Dut, topical min, 1.5mm roller
The conversation is about hair loss progress using treatments such as Dutasteride, topical minoxidil, and a 1.5mm roller.
community Soy Isoflavones and Capsaicin for Hair Growth
The conversation discusses using soy isoflavones and capsaicin for hair growth. It also mentions treatments like Minoxidil, finasteride, and RU58841.
community Will vellus hairs in thinning areas go terminal if you go all out?
A trans woman is using finasteride, minoxidil, microneedling, and HRT to address hair loss, with noticeable improvement in hairline shape and presence of vellus hairs. She is considering hair transplants if these treatments don't yield desired results within a year or two.
community Pyrilutamide binding affinity is similar to RU
Comparing the effectiveness of RU58841, Pyrilutamide and CB-03-01 as treatments for hair loss, with people discussing different aspects such as binding affinity, time of inhibition, safety data and cost.
community Topical to oral minoxidil conversion
community How many non responders to minoxidil become responders with 1.5mm microneedling?
The conversation discusses using 1.5mm microneedling to improve responses to Minoxidil for hair loss. One user humorously suggests more aggressive microneedling.
community cant use minoxidil, is there anything else that can mimic the results?
The conversation is about alternatives to minoxidil for hair growth, as the original poster experienced chest tightness from using it. They are currently using finasteride and considering options like rosemary oil, pumpkin seed oil, and other topical treatments, but acknowledge that minoxidil and finasteride are the most scientifically supported treatments.
community A list of top hyperresponders of /tressless with a data array for studying the phenomenon
The conversation is about treatments for androgenetic alopecia, focusing on hyperresponders. Treatments include Minoxidil, finasteride, RU58841, leg training, and cold therapy.
community RU58841 is a scam until proven otherwise
community When will FAK Inhibitors / Standford Hydrogel be on the market for hair transplants?
The conversation discusses the delay in bringing FAK inhibitors and Stanford's hydrogel to market for hair transplants, with a preference for FAK inhibitors over Verteporfin due to their superior potential in preventing scarring. The user expresses frustration over the slow progress and hopes for faster development by companies like FAKnostics.
community Slow responder: Progress stalling on dut, stabilization and thin fuzz but the hairs aren't going terminal. I wonder what options I have left are
A 43-year-old male has been using oral minoxidil, finasteride, and dutasteride for hair loss, with some stabilization and thin hair growth but no significant cosmetic improvement. He is considering increasing microneedling frequency and exploring other options, as he is concerned about the lack of terminal hair growth.
community Proposed new pathogenesis model for androgenetic alopecia (AGA)
The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.
community Rare case: AGA recovery with vitamin D alone (case study)
Vitamin D deficiency can hinder hair recovery, and addressing it may help with hair loss. Hair loss may result from various issues like excess DHT, vitamin deficiency, or scalp inflammation.
community How much scalp dht does dutasteride 1mg, 1.5mg, and 2mg block?
Dutasteride at 0.5mg blocks 50% of scalp DHT, while higher doses like 1mg and 2.5mg block more, with 2.5mg blocking up to 80%. Some users report better results with lower doses, and there's confusion about the effectiveness of different dosages on scalp versus serum DHT.
community Anyone try Ell-Cranell or Eucapil?
Ell-Cranell and Eucapil are discussed as hair loss treatments, with Ell-Cranell being a weak estrogen and DHT inhibitor that may reduce hair loss without systemic side effects. Alfatradiol is the active ingredient in these products.
community 0.25 alfatradiol or 0.5 Pyrulitamide ?
The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.
community For using ethanol for RU, do I use denatured or non-denatured?
The conversation discusses using non-denatured ethanol for RU58841. Treatments mentioned include Minoxidil, finasteride, and RU58841.
community PP405 is still being evaluated for safety over efficacy.
Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss. PP405 is still under evaluation for safety.
community Tropical growth stimulants other than minoxidil
The conversation discusses alternative hair growth treatments to minoxidil, including Stemoxydine, Tretinoin, adenosine, Baicalin, castor oil, Latanoprost/bimatoprost, and Redensyl. Users share their experiences and opinions on the efficacy of these treatments.
community Glycine supplementaion is said to strongly upregulate 5-alpha Reductase (5-ar) Activity
Glycine supplementation may increase 5-alpha reductase activity, potentially affecting hair loss. Users discuss its impact on hair fall and its role in the body.