PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.
A user shared their positive experience 9.5 months after a hair transplant at Diamond Hair Clinic in Istanbul, Turkey, mentioning the use of dutasteride, vitamin tablets, and minoxidil shampoo. They expressed satisfaction with the procedure and would choose to do it again.
The user shared their 5-year hair journey, including a recent hair transplant of 2600 grafts, and their routine of using dutasteride, oral minoxidil, and ketrel. They are hopeful for high-density results and recommend starting treatment early.
A 28-year-old used oral finasteride and minoxidil, and underwent two hair transplants in Turkey, with a total of 3150 grafts, resulting in a natural-looking hairline. The first procedure cost £3300, and the second was a free touch-up, with additional costs for flights and accommodation.
A user shared their 1-year crown transformation after a second hair transplant with 4000 grafts, using finasteride, minoxidil, and vitamins. Another user commented that while the crown has filled in, they expected more coverage from 4000 grafts and suggested a possible shedding phase.
A 36-year-old considering a fourth hair transplant is advised to either shave his head or use a hair system due to poor results from previous transplants and late medication use. He plans to consult top surgeons and adjust his current treatments, including finasteride and minoxidil.
HMI-115, a potential treatment for hair loss that has been reported to produce significant regrowth in bald areas. It is the closest thing to a cure currently available and has raised hope that it could make hair transplants obsolete.
Exploring the potential of using verteporfin during hair transplants to minimize scarring and regenerate follicles, as well as discussing a possible standardized protocol for this treatment.
The user experienced hair regrowth after using finasteride for three months and microneedling with a dermapen for a month and a half. Many responses confirm noticeable hair thickening, though some suggest waiting longer for more definitive results.
The user started using 1mg finasteride and Regaine foam post-hair transplant, noticing significant hair growth at three months. They experienced testicular cramps as a side effect but no other issues, and are considering microneedling for further improvement.
The user is experiencing hair loss and is using oral finasteride, considering adding RU58841 and microneedling, and planning a hair transplant. They are seeking advice on whether to wait for treatment results or proceed with the transplant.
A 28-year-old man had a hair transplant in India, choosing not to start finasteride due to past side effects with other medications but will use minoxidil for six months post-surgery. He researched and selected a clinic in Mumbai with a high reputation, underwent a 9-hour procedure for $965, and is optimistic about the results.
Researchers are working on regenerating hair follicles using stem cells, but a cure for baldness is still years away. Current treatments mentioned include Minoxidil, finasteride, and RU58841.
PP405 may induce new hair growth but cannot revive completely dead follicles, and its effectiveness on hairlines is uncertain. It is expected to be available by mid-2028, but users are advised to manage expectations and consider using other treatments like minoxidil and finasteride.
User fought hair loss with Derminator microneedling, topical and oral minoxidil, and a 2000 FUE hair transplant. Derminator was a game changer, preventing further loss.
A user is considering creating a mobile app to track hair transplant recovery, including daily progress, photos, and care instructions. They seek feedback on whether such an app would be helpful for others.
A 3-month update on a microneedling-only project to treat hair loss, which has not had significant results in terms of thicker hair but may have seen some acceleration in hair growth and an increase in vellus hairs. The user plans to continue the journey for 6 months before making any changes, such as adding minoxidil or finasteride.
The post discusses a user's struggle with hair loss and the ineffectiveness of finasteride. Suggestions from the conversation include trying oral minoxidil and considering a 3200 graft hair transplant.
Hair loss treatments discussed include leave-in conditioner, volumizing powder, styling products, and hairspray for thicker appearance without fibers. User shares routine and product suggestions for people with thin hair that lacks volume.
The conversation is about hair regrowth using high-dose dutasteride, oral minoxidil, and microneedling. Users discuss seeing tiny hairs and hope they will become terminal, with advice to use derma rolling weekly for better results.
A 34-year-old male documents his hair growth journey using the iRestore Elite laser cap, biotin, and Pure Synergy Organic Superfood Capsules, after unsuccessful hair transplant and previous treatments with minoxidil and finasteride. Replies suggest using finasteride or dutasteride instead and caution against excessive use of the laser cap.
Transplanting mice skin to humans is not feasible due to immune rejection, but some suggest genetic modification or immune suppression could make it possible. Xenograft hair transplants are discouraged.
A 32-year-old man had a successful hair transplant in Atlanta, using 1mg finasteride and 5% topical minoxidil daily, which greatly improved his confidence and appearance. He spent about $13,000 and is very satisfied with the youthful results and increased happiness.
The user has been taking oral finasteride for 2 months, experiencing more hair loss but noticing some fuzzy hair growth on the scalp. They are questioning if this new hair growth is significant.
Promising hair loss treatments in clinical trials include Pyrilutamide, GT20029, CB-03-01, and PP405, with potential market releases between 2027 and 2029. Hair cloning remains experimental and expensive, while existing treatments like finasteride, minoxidil, and microneedling continue to be used.
A user shared their 4-month hair restoration progress using minoxidil with finasteride, oral finasteride, and micro needling. The community responded positively, praising the results and the user's happy demeanor in photos.
ET-02 showed significant hair growth in five weeks, outperforming minoxidil, with a non-hormonal mechanism that avoids side effects of treatments like finasteride. A phase 2 trial is planned to further assess ET-02's efficacy and safety.
PP405 is a promising new treatment for hair loss that activates dormant stem cells in hair follicles, potentially bypassing the effects of DHT. It is currently in phase 2 trials and could be available between 2027 and 2030, but it is not considered a definitive cure.
Hair loss treatments discussed include promising Pyr available online and Verteporfin dosing after FUE for follicle regeneration, but no updates on SCUBE3.
A user shared their 14-day recovery progress after a 3450 graft FUE hair transplant in Turkey, noting faster healing possibly due to hydrolyzed collagen supplements. They asked if others had similar experiences with or without such supplements.