Search

everythinglearnresearchcommunity

for

Search:↓

The trial for TDM-105795 has been completed, and it was in phase 2A. The discussion seeks input on the next phases, 2B or 3, based on safety and efficacy.

The conversation is about finding shampoos with Piroctone Olamine in the US for itch relief, as the user has not found relief with Keto shampoo, oral Dutasteride, and oral Minoxidil. Users suggest alternatives like Neutrogena T/Gel and online options, but note availability and price issues.

Kintor Pharma has started a Phase II trial in China for GT20029, a potential new treatment for hair loss. Participants are discussing the significance, potential release dates, and comparing it to other treatments and technologies like stem cell hair transplants and SAMIRNA.

An 18-year-old is using a high-dose hair loss treatment with 40mg daily dutasteride, finasteride, minoxidil, tretinoin, and topical bicalutamide. Despite health risk concerns, especially liver issues, they report hair regrowth progress and intend to continue the regimen.

The user plans to maintain and improve hair health using finasteride, a balanced diet, exercise, and regular hair care, while avoiding minoxidil. They intend to share weekly updates on their progress.

The conversation humorously discusses George Clooney's hair and aging, suggesting he switch to dutasteride for his temples. It also mentions minoxidil and finasteride, debating the effects of hair dye and styling on his appearance.

User discusses using finasteride, ketoconazole, fish oil, nettle root, saw palmetto, emu oil, and plans to start minoxidil for hair loss. They report maintaining hair with minor side effects like slightly lower libido and watery semen.

Taking dutasteride daily with finasteride is more effective in reducing hair loss and itching than taking dutasteride four times a week. The combination reduces shedding and anxiety.

Pelage Pharmaceuticals announced positive Phase 2a trial results for PP405 in hair loss therapy. The conversation discusses the delay in publishing full results and the need for further trials and approvals.

The user shared their experience with dutasteride for hair loss prevention, noting side effects like muscle weakness and brain fog, and observed increased testosterone levels. They recommend starting with a low dose and adjusting based on individual needs and blood work results.

Salicylic acid is discussed as a potential treatment for hair growth. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

A user who was able to get dutasteride for free with their insurance, and another user mentioning that finasteride is only covered if it is used for medical reasons.

Topical finasteride in Europe is often seen as less effective than oral forms, with users suggesting alternative application methods for better results. Many prefer oral finasteride due to cost and effectiveness.

Using Dutasteride as a hair loss treatment and its potential benefits, including availability in certain countries without a prescription and lower side effects than Minoxidil or RU58841.

Flax seeds may block DHT and prevent hair loss. Users discuss its potential benefits, with one noting it likely has negligible effects on hair but is good for the diet.

The user is concerned about potential alopecia areata. They are seeking advice on whether this condition is normal.

Dutasteride's half-life varies with dosage, and lower doses can be effective with fewer side effects compared to finasteride. Some users report different side effects with dutasteride and finasteride, and extreme dosages of dutasteride are unnecessary and potentially harmful.

The post and conversation are about a hair loss treatment stack without finasteride or dutasteride. The suggested treatments include Alfatradiol, Koshine826, Ketoconazole lotion, Minoxidil, microneedling, Tretinoin, and Stemoxydine.

Clascoterone 5% shows potential for hair thickening and darkening, especially when combined with treatments like finasteride. It may be a good alternative for those who experience side effects from other treatments.

AI advancements, like AlphaFold, are speeding up drug discovery for hair loss, promising more effective treatments. Current options like minoxidil and finasteride have limitations, but new developments could improve solutions in 5-10 years.

Natural vitamins like pumpkin seed oil, saw palmetto, and ecklonia cava are discussed for their potential to lower DHT levels. They may work similarly to finasteride but are significantly weaker.

The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

The user experienced significant hair improvement after 15 months of treatment, using finasteride initially, then switching to dutasteride, and recently adding topical minoxidil. They credit their progress to dutasteride and support from Haircafe, a YouTuber.

A person experienced hair regrowth after reducing testosterone levels and using saw palmetto tincture and Alpecin shampoo. Other users suggested treatments like Nizoral shampoo, Aldactone, and supplements for hair loss.

Female considering adding topical anti-androgen, seeks advice on RU58841 or pyrilutamid's binding affinity compared to spironolactone.

New treatments for AGA are emerging, including pyrilutumide, gt0029, scube3, kx-826, and pp405. Verteporfin is mentioned as a promising option.

Beta-sitosterol may inhibit 5-alpha reductase type 2 enzyme, potentially reducing DHT levels and promoting hair growth, similar to finasteride but possibly with fewer side effects. Its effectiveness and side effects compared to other treatments like saw palmetto and finasteride remain uncertain due to limited research.

Woman uses antiandrogens for hair thinning prevention, experiences severe dry eye with finasteride. Asks if dutasteride could be better despite potential for worse dry eye.

Hair loss discussion includes Minoxidil, Finasteride, and RU58841 treatments. User seeks where to buy topical Adenosine.

A 19-year-old plans to start Dutasteride 0.5mg three times a week to combat genetic alopecia and preserve hair density, with concerns about potential shedding before prom. Users suggest starting the treatment after prom to avoid shedding, and provide advice on where to purchase the medication.