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Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

A user improved their hair health by taking 50,000 IU of vitamin D3 weekly due to a deficiency. Others discussed the potential link between vitamin D and hair growth, with some sharing similar experiences and emphasizing the importance of monitoring vitamin D levels and consulting with doctors.

The reasoning for GSK's approval of dutasteride for hair loss in Japan and South Korea but not the US, with alternatives such as finasteride, minoxidil and RU58841 mentioned.

A user shared their experience with an FUE hair transplant at Dr. Cinik's clinic in Istanbul, detailing the procedure and recovery. They used Minoxidil and finasteride before the transplant and continued finasteride post-op, stopping Minoxidil as advised.

The user is considering using "Grow Gorgeous Intense Hair Density Serum" alongside Minoxidil and is currently taking Finasteride. Some users doubt the serum's effectiveness, while others suggest it may help with hair strength and thickness, but opinions are mixed.

A user shared their experience of using finasteride for hair loss from ages 29 to 37, stopping due to side effects like low libido, and later starting testosterone therapy, which improved their well-being. The discussion includes various opinions on the effects of finasteride and testosterone on hair loss, libido, and overall health, with some users questioning the correlation between finasteride and low testosterone.

Doctors in the UK are hesitant to prescribe finasteride for hair loss, leading many to seek it from online pharmacies. Users discuss side effects and alternative treatments like minoxidil, with some opting for online purchases due to ease and availability.

Switching generic finasteride manufacturers can reduce side effects while maintaining effectiveness. Different fillers in generics may affect bioavailability and cause varying side effects.

Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

The user is pleased with hair regrowth after three months of using minoxidil and plans to start finasteride for further improvement. They experienced initial shedding but no significant side effects and are considering finasteride despite some medical hesitations.

Users discuss using pyrilutamide for hair loss, seeking alternatives to 5AR inhibitors. They mention using minoxidil, ketoconazole shampoo, and RU58841.

Laser caps are found to be more effective than 5% minoxidil for treating hair loss, and when combined with minoxidil, they are even more effective. Some users report positive results with laser treatments, while others see no change; the devices are FDA approved, but opinions on their efficacy vary.

A 20-year-old male's significant hair growth after two months of using 0.25mg Finasteride. The discussion includes varying opinions on the effectiveness and side effects of the treatment, with some users planning to try or adjust their Finasteride dosage.

Liquid minoxidil makes hair sticky and stiff; users suggest oral minoxidil or minoxidil foam as alternatives. Applying minoxidil four hours before showering can help with absorption.

The user experiences irritation from alcohols in minoxidil and is considering alternatives like trichosol mixed with polyethylene glycol or DMSO. They seek advice on the best nonirritating option.

OP is seeking recommendations for thickening tonics and decides to try Aveda thickening tonic after a suggestion. Another user recommends hair powder as an alternative.

The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.

The conversation discusses Melatonin's potential benefits for AGA and a product called "Asatex" by ASATONA AG. The company was uncooperative when contacted for purchase inquiries.

The user is experiencing a burning sensation from using minoxidil and is considering trying an alcohol-free version with added azelaic acid. They are also using finasteride and seeking reliable, low-cost alternatives for minoxidil.

The user is experiencing irritation from using PG with RU58841 and is seeking alternative solutions like K&B in the UK. They report redness, itchiness, and flaky skin from the current treatment.

The user is experiencing scalp irritation from a compounded treatment of finasteride, minoxidil, and tretinoin. They are considering switching to a non-alcohol, propylene glycol-free formula with a lower tretinoin percentage to reduce irritation.

A user with AGA uses topical spironolactone 2% due to side effects from the oral form and is concerned about its use during conception and breastfeeding. They seek alternatives to prevent AGA relapse while planning pregnancy and after childbirth.

A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

Topical minoxidil can cause water retention, making the face appear swollen. Switching from liquid to foam and reducing application frequency may help; using dandelion root extract as a diuretic is also suggested.

A natural compound called C3A from Aronia Chokeberry can help prevent hair loss by counteracting the effects of DHT. The user has been taking 50 grams of dried organic Aronia Chokeberry daily for 30 days and will update with photos in 60 days.

The user experienced side effects from spironolactone and is seeking alternatives for androgenetic alopecia (AGA), considering saw palmetto but unsure of its effectiveness. They are also exploring the possibility of using topical spironolactone, despite availability challenges.

AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.

Crushing spironolactone pills and combining them with minoxidil for topical application may be effective for hair loss, with the addition of finasteride suggested. Adding rosemary and peppermint oils can help mask the unpleasant smell.

The user is experiencing scalp irritation from using tretinoin and alcohol-based hair loss treatments like stemoxydine. They find that Aquaphor helps with the pain but is difficult to apply in hairy areas.

A user is asking about the effectiveness of "Minoxidil tincture 5% Purified Water" compared to other Minoxidil 5% products. They experienced itching and redness with other Minoxidil products and suspect they might be allergic.