A user's hair loss progress after 4 months of using a topical fin and min mix, with responses from other users about their experience with the same treatments.
The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.
The conversation discusses using a liposomal gel with Adenosine and caffeine for hair loss, questioning if caffeine's role as an adenosine receptor antagonist might counteract the benefits of Adenosine or worsen hair loss.
Dutasteride is more effective than finasteride for hair loss, especially at the crown and midscalp, but both have similar side-effect profiles with low incidence of sexual adverse events. Improvement is measured visually, and significant results may take over 12 months to appear.
The post discusses the potential of GT20029 in treating hair loss, questioning if it will replace finasteride or be used alongside existing treatments. A reply indicates that its role is still uncertain.
A 23-year-old male has been using 0.25mg finasteride daily for 4.5 months to address early-stage male pattern baldness, with positive results and no significant side effects. He plans to continue with this dosage and may consider increasing it or adding minoxidil if necessary.
The user is experiencing hair regrowth after 4.5 months using 1 mg finasteride daily, 5% minoxidil twice daily, and ketoconazole 2% shampoo. Suggestions include microneedling and possibly a hair transplant for further improvement.
The user reported positive results with thicker and denser hair after four months of taking 1mg oral finasteride daily, without using minoxidil. Some users discussed potential side effects like mild testicular ache and debated the timing and benefits of adding minoxidil to the regimen.
The conversation discusses the use of coenzyme Q10 as a potential aid for androgenetic alopecia, alongside dutasteride. The user is seeking feedback on whether coenzyme Q10 improves or worsens hair condition.
Topilutamide is a potential hair loss treatment between Clascoterone and RU58841. Users discuss finding Topilutamide powder and its possible benefits for those who can't afford or tolerate other treatments.
The user is using oral finasteride, topical minoxidil, Nizoral, dermarolling, a hair thickening conditioner, and hair vitamins for hair loss treatment. They stopped taking testosterone due to medical reasons and are now technically on estrogen, but it's unclear if this impacts their hair growth.
A 36-year-old man restarted hair loss treatment after a break, using topical Minoxidil 5% twice daily, topical Finasteride 0.01% daily, and Ketoconazole 2% three times a week, along with supplements like Vitamin B12, D3, C, Biotin, Omega-3, zinc, and copper. He avoids oral Finasteride due to side effects and plans to evaluate progress after a year.
The conversation discusses concerns about using cordyceps while on dutasteride due to potential DHT increase, with OP experiencing hair loss after using creatine. OP is advised to stop creatine and give dutasteride more time to evaluate its effectiveness.
The conversation is about the progress of verteporfin in hair loss trials, with users expressing curiosity about its effectiveness and updates. Specific treatments mentioned include FUE (Follicular Unit Extraction) combined with verteporfin, with one reported case of donor area regrowth after a year, and three patients being monitored post-treatment by Dr. Bloxham with monthly updates on YouTube.
The user has been using finasteride for over four years with minimal side effects, successfully stopping hair thinning and achieving some regrowth. They shared progress photos, but some commenters requested clearer pictures of the crown to better assess the treatment's effectiveness.
Dr. Toyos is recruiting more participants for a larger trial on hair loss treatments. The discussion mentions Minoxidil, finasteride, and RU58841 as potential treatments.
Caffeine may promote hair growth and potentially inhibit 5-α-reductase activity in hair follicles, but its effectiveness and systemic impact remain unclear. Users discuss using topical caffeine solutions, with some experiencing no side effects compared to finasteride.
Pyrilutamide is considered by some as an alternative for those avoiding 5AR inhibitors like finasteride and dutasteride, but opinions on its effectiveness vary. Some users report similar results with fluridil and pyrilutamide, while others find pyrilutamide less effective compared to prescription treatments.
GT20029 is discussed as a potential treatment for androgenetic hair loss by targeting androgen receptors, unlike finasteride which reduces DHT broadly. Concerns include its effectiveness, genetic variations in androgen receptors, and availability, with some skepticism about its potential as a true alternative.
Dr. Bloxham's 9-month update on FUT scar revision with Verteporfin shows promising results. Excitement is high for FUE, which appears highly effective based on Dr. Barghouthi's findings.
PP405 may not need daily use like minoxidil, but finasteride might still be needed to maintain hair regrowth. PP405 reawakens dormant hair follicles, potentially offering a long-term solution, though not a permanent cure.
The user shared a 4-month update on hair loss treatment using finasteride, minoxidil, and derma stamps, showing significant progress. The user experienced no side effects and plans to continue the treatment, updating monthly.
Creatine may increase DHT levels, potentially leading to hair loss, but whey protein and BCAAs are generally considered safe for hair. Finasteride can mitigate creatine's effects on hair loss.
KPV, a peptide patented by L'Oreal, may promote hair growth and reduce hair loss by extending the anagen phase and has anti-inflammatory properties. It could be combined with treatments like minoxidil for enhanced effects.
The post is about whether there is any additional benefit to using alfatradiol or other estrogen treatments for hair loss if someone is already using finasteride, dutasteride, or an androgen receptor inhibitor like RU58841, pyrithione zinc, or fluridil.
The user has been using 1mg oral finasteride daily for four years, experiencing significant hair regrowth and increased testosterone levels without negative side effects. They advise patience and monitoring for side effects, noting that their hair continues to improve with this treatment.
PP405 updates are seen as vague and lacking substance, causing frustration among users. Some users report positive effects from using minoxidil and dutasteride, while others remain skeptical about new treatments.
The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.
Eirion Therapeutics is recruiting for phase 1 of ET-02 in Texas, which showed promising hair growth results in non-clinical studies. ET-02 demonstrated significantly more hair growth compared to Minoxidil.
Hair loss treatments RU55841, CB-03-01, and Eucapil were discussed, with concerns about needing increased dosages over time and potential side effects. A user suggested that CB's results could be due to various factors and that combining it with finasteride might slow down any upregulation.