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Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.

The user experienced worsening hair thinning despite using finasteride, minoxidil, and ketoconazole shampoo, and switched to dutasteride five months ago. They are considering adding tretinoin and microneedling to their routine for better results.

The user stopped using Alfatradiol after 4 months due to no hair improvement and side effects like dry scalp and gallbladder pain. They are considering trying topilutamide, which is suggested as an alternative.

The post discusses a successful hair loss treatment involving a hair transplant, finasteride, and minoxidil. The user underwent a 2000 graft hair transplant at the hairline in a clinic in Sweden.

A 19-year-old transgender individual is experiencing worsening temple recession despite taking female hormones and 1.25mg finasteride. They are seeking advice on additional treatments to address hair loss.

The conversation is about dealing with hair shedding due to seborrheic dermatitis and recent illness. Recommendations include treating seborrheic dermatitis with ketoconazole, correcting vitamin D deficiency, and improving sleep.

A user shared their hair loss journey, showing improvement after starting finasteride, dutasteride, minoxidil 5%, and microneedling. They are curious about their degree of baldness and why their hair has thinned.

An 18-year-old is using topical minoxidil 5% and derma rolling weekly for hair regrowth after shaving their head, while also addressing vitamin D deficiency and thyroid imbalance. They are questioning if the changes observed are signs of regrowth.

The user shared their 12-month hair regrowth progress using 1mg finasteride, 5mg oral minoxidil, and topical minoxidil. They also used a derma stamp weekly and treated seborrheic dermatitis with Mometasone and Nizoral.

The user follows an intensive hair loss protocol including dutasteride, biotin, black tea, pumpkin seed oil, peppermint shampoo, rosemary conditioner, mukemame, soy milk, lycopene, garlic, magnesium, chamomile, spicy food, citrus bergamot, zinc, multivitamins, kefir, and Greek yogurt. They plan to alternate between pumpkin seed oil and safflower oil and will share before and after pictures.

The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.

Two twins who used Minoxidil, finasteride and dermarollers to treat their androgenic alopecia over a 10 month time period. The user is providing details on the process they use for dermarolling.

The user is using 5% Minoxidil, a 1 mm derma stamp, Vitamin D3, Zinc, and anti-dandruff shampoo for hair regrowth. They plan to consider DHT blockers like finasteride in the future.

A user shared their hair loss journey, starting treatments with topical minoxidil and finasteride at 17, and later adding oral versions and dutasteride by age 20, but still experiencing hair loss. Others suggested that the treatments have likely slowed the progression, and some recommended considering a hair transplant or adjusting medication, while expressing concerns about the potential side effects of starting such treatments at a young age.

Tressless GPT is now free and accessible for hair loss advice. Treatments discussed include Minoxidil, finasteride, RU58841, dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

A user shared a 10-month update on their hair loss treatment, including a hair transplant of 2300 grafts and 7.5 months of using a topical minoxidil/finasteride solution and ketoconazole shampoo. They expressed regret for not starting the medications sooner and reported side effects like heart palpitations, which improved after cutting out caffeine.

A 28-year-old male is using Minoxidil 5% with tretinoin and azelaic acid for hair loss and is considering finasteride but is concerned about side effects. He seeks advice on recovering his temple area.

A 42-year-old is using dutasteride, oral and topical minoxidil, ketoconazole, and a dermaroller for hair loss, with noticeable progress after six months. They are questioning if further gains are possible and considering stopping the dermaroller, as advised that future improvements may only involve hair thickening.

The user has been using topical minoxidil and finasteride for hair loss, with some regrowth at the temples but continued hairline thinning. The dermatologist suggested possible telogen effluvium due to stress and deficiencies, prescribed oral minoxidil, and may consider dutasteride if the condition doesn't improve by January 2026.

A 36-year-old man with androgenetic alopecia suspects copper and zinc deficiencies may be accelerating hair loss and is supplementing copper to address this. He is also monitoring blood sugar levels due to previous prediabetes concerns and plans to test for insulin resistance.

The user has been using finasteride for four years and topical minoxidil with microneedling for a year but has not seen significant results in slowing hair loss. They are considering trying dutasteride despite concerns about its intensity, and others suggest trying oral minoxidil or combining treatments for better results.

The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

The user is experiencing hair regrowth after 3.5 months using finasteride, dutasteride, oral minoxidil, dermastamping, and ketoconazole shampoo. They are hopeful about the progress but note that topical minoxidil was ineffective for them.

A female, aged 17-18, is experiencing significant hair loss, feeling hopeless despite trying various treatments like leave-in conditioners, omega-3s, supplements, sulfate-free shampoo, and biotin. She is distressed as her hair continues to thin, affecting her body image and self-esteem.

A 27-year-old male with androgenetic alopecia has been using finasteride, topical minoxidil, and microneedling for over six months to stabilize hair loss and prepare for a potential hair transplant. While some users suggest switching to dutasteride and increasing minoxidil usage, others note minimal progress, with some hair stabilization but concerns about thinning at the crown.

A user shared progress pictures after 16 months of using 1 mg finasteride daily and 2% ketoconazole and ZP shampoo. They experienced hair loss after severe weight loss and are concerned about potential shedding from starting minoxidil.

The conversation discusses various treatments for hair loss, including finasteride, minoxidil, dutasteride, microneedling, and checking for nutrient deficiencies. Some users suggest adding hydrocortisone butyrate, low-dose progesterone, or tretinoin to treatment regimens, while others recommend cosmetic solutions like Toppik hair fibers or shaving the head.

The conversation discusses hair loss treatments, focusing on iron supplements for low ferritin levels and considering finasteride and minoxidil if thinning persists. There is debate over starting with finasteride versus dutasteride, with some users advocating for dutasteride due to its potency, while others caution about potential side effects.

A user experienced rapid hair loss and was prescribed Desonide cream for mild Alopecia. They are seeking feedback on its effectiveness and potential side effects.

The user "baselinesims" shared their progress in treating hair loss using 1mg oral finasteride, 1ml topical minoxidil, 0.5ml topical dutasteride, keto shampoo, cosmerna, and micro needling. They are happy with the progress so far, with diffuse thinning being taken care of and baby hairs showing up. They plan on getting a hair transplant in the future. Other users commented on the improved appearance and mentioned that the lighting in the photos may affect the comparison.