community Trial for TDM-105795 update from research office
The trial for TDM-105795 has been completed, and it was in phase 2A. The discussion seeks input on the next phases, 2B or 3, based on safety and efficacy.
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840-870 / 1000+ resultscommunity Discussion: Evidence Refuting the "24-Hour Rule" for Minoxidil and Dermarolling
The 24-hour waiting period after dermarolling before applying minoxidil is unnecessary. New research supports the simultaneous application of minoxidil with microneedling for better hair growth results.
community Intermittent fasting triggers hair loss in study (suppresses hair follicle regeneration)
Intermittent fasting may suppress hair follicle regeneration, but opinions vary on its impact on hair loss. Some users report no negative effects or even hair improvement while using treatments like finasteride and minoxidil.
community Anybody getting RU58841 from RUdirect?
RU58841 is discussed for hair loss treatment, with questions about its legitimacy from RUdirect. Minoxidil and finasteride are also mentioned as treatments.
community Minoxidil and skin aging worry - which prevention methods (platelet rich plasma, microneedlig, mesotherapy, stem cells, co2, ultherapy, ...)
User started minoxidil, noticed forehead lines and dark circles, and asked for non-invasive skin aging prevention methods. Another user suggested using tretinoin and hyaluronic acid for long-term benefits.
community 4 months min 1.5 times a day, 3 months fin 1mg, microneedling once a week
The user has been using Minoxidil 1.5 times a day for 4 months, Finasteride 1mg for 3 months, and microneedling once a week. They are unsure about their progress due to colorblindness, but another user noted some improvement.
community If RU58841 is such an effective anti androgen
RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.
community 1.25 mg Fin for a year, and very inconsistent oral min for 3 months.
The user experienced significant hair regrowth using 1.25 mg finasteride daily and inconsistent oral minoxidil, with no side effects reported. Finasteride primarily increased hair density, while minoxidil contributed to thicker, healthier hair.
community Persistent Shedding on 2.5mg Oral Minoxidil: No Reduction After 13 Weeks
The user experienced prolonged hair shedding after restarting oral minoxidil (OM) at 2.5 mg in September 2023, following a break due to hypertrichosis. Despite seeing regrowth, the shedding has not decreased after 11 weeks on the increased dosage.
community Amplifica AMP-303 study results are expected late this summer
Results for Amplifica's AMP-303 hair loss treatment study are expected late summer 2024. The study, fully enrolled in Q1 2024, focuses on safety and tolerability.
community Anybody have any remedies for an irritated scalp with treatment?
The user is experiencing scalp irritation after increasing their finasteride and minoxidil dosage with tretinoin and is considering reducing application frequency. They seek advice on managing the irritation.
community 6 months - 0.5mg dutasteride, 5mg oral minoxidil, 80mg Ru58841, microneedle 1.5mm every other week
User started hair loss treatment 6 months ago using 0.5mg dutasteride, 5mg oral minoxidil, 80mg RU58841, and microneedling 1.5mm every other week. They experienced significant hair regrowth and no side effects, with others encouraging continued progress.
community Should I give minoxidil a try or should I wait to see if I can get any more results from my regimen (fin, Ru58841, microneedling) almost at the 1year mark since starting also wondering if I can mix my ru58841 powder into minoxidil and just use that as my solvent
The conversation discusses whether to add minoxidil to an existing hair loss treatment regimen that includes finasteride, RU58841, and microneedling. Some users suggest trying minoxidil and monitoring for side effects, while others advise waiting to see if current treatments improve results after one year.
community 2 month difference, not missing a single dose.
The user experienced significant hair regrowth over two months using a regimen of daily minoxidil, daily finasteride, and weekly microneedling. They reported no major side effects, except for temporary watery loads, and emphasized the importance of consistency.
community Any ru58841 users here, where do you get it from?
The conversation is about sourcing RU58841 for hair loss treatment, with a focus on finding reputable sellers. The user plans to use 10mg/ml daily, split into two doses, prioritizing quality over price.
community Low Estradiol while on 1mg Fin, what should I do?
A user on 1mg finasteride for a year has low estradiol levels but no significant symptoms, and others suggest monitoring without immediate concern. Some users discuss potential effects of low estrogen, like low libido, but the user reports no erectile dysfunction.
community Finasteride/ Dut dosage advice
A 33-year-old user is seeking advice on adjusting their hair loss treatment, which includes daily finasteride, oral minoxidil, and various supplements. They are considering switching to alternate-day dosing of finasteride or dutasteride and are concerned about potential shedding and effectiveness.
community cb-03-01 research chem (winlevi/clascoterone cream)
The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.
community Effect of melatonin on aromatase expression
Melatonin's effect on aromatase expression is unclear, with studies showing both increases and decreases. Hormonal impacts are complex and inconsistent, similar to changing health advice on other substances.
community 3 month progress with fin, min, once weekly microneedling + hair supplements and half hour daily scalp massage
A man's successful hair regrowth after using finasteride, minoxidil, microneedling, hair supplements, and scalp massages. He noticed significant improvements and is excited about future progress.
community Crown regrowth - Fin 1mg ED, Min Foam once Daily
User shared progress on crown regrowth using Minoxidil Foam, oral Minoxidil 2.5mg daily, and Finasteride 1mg daily. They experienced initial headaches with oral Minoxidil, had a hair transplant, and are seeing regrowth but with thin hairs.
community Increased Shedding After 1 Month on 0.25 mg Finasteride Despite Initial Improvement
The user experienced increased hair shedding after one month on 0.25 mg finasteride, despite initial improvement. This shedding may be a normal phase in the hair cycle and could improve in the coming months.
community Microneedling sometimes feels like
Microneedling for hair loss is discussed, with users mentioning using 0.6mm needles twice a week. Treatments like Minoxidil, finasteride, and RU58841 are implied but not directly mentioned.
community 25M with Uneven Thinning Despite Oral Minox, Considering PRP and Microneedling
A user is experiencing uneven hair thinning and has tried topical minoxidil without success and finasteride with adverse effects. They are considering microneedling and PRP treatments while avoiding finasteride, and another user suggests trying dutasteride as an alternative.
community 1 year Fin/Min + sporadic use of RU58841 (a few months here or there)
The conversation is about a person's one-year progress using finasteride and minoxidil for hair loss, with intermittent use of RU58841, showing improved hair quality, density, and thickness without side effects. Users complimented the improved appearance and suggested the longer hair also enhanced their look.
community Dut increase dose after year of no progress?
The user has been on dutasteride and oral minoxidil for a year with no progress and is considering increasing the dutasteride dose or adding RU58841. Other users suggest consulting a doctor, trying derma needling with topical minoxidil, and note that hair loss treatments can have varying effectiveness.
community day 107 of kx826 .5% . 1+ years on topical minoxidil.
The user has been using topical minoxidil for over a year and added kx826/pyrilutamide to improve hair growth, avoiding finasteride due to side effects like lowered libido and panic attacks. They report positive results with reduced shedding and healthier hair, particularly in areas previously unresponsive to minoxidil.
community One year anti androgen update CROWN
User used Finasteride, Dutasteride, and Minoxidil for one year to treat hair loss. They discussed possibly trying RU58841 or pyrilutamide in the future.
community 2/3 month update (Telogen Effluvium, diffuse thinning) 5% Minoxidil
User experienced telogen effluvium and diffuse thinning, started using 5% minoxidil two months ago, and resolved several deficiencies. They report noticeable improvement in hair health and plan to update progress in a month.
community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.
ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.