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      community Fin working well but dull orgasm

      in Update  21 upvotes 9 months ago
      A 31-year-old experienced significant hair regrowth after switching to oral Finasteride but reported dull orgasms as a side effect. Users suggested waiting for the body to adjust, reducing the dosage, or switching to topical Finasteride to manage side effects.

      community Insulins impact on androgen levels

      in Research/Science  16 upvotes 4 years ago
      Controlling insulin levels through intermittent fasting and a low glycemic diet may improve hair quality by reducing androgens. It's important to maintain proper nutrition, including electrolytes and protein, during fasting.

      community Who won’t respond to minoxidil? (Studies)

      in Research/Science  33 upvotes 4 months ago
      Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.

      community Finasteride affects both 5a reductase and 5b reductase

       6 upvotes 6 years ago
      Finasteride not only inactivates the 5a reductase enzyme but also affects the 5b reductase enzyme in a dose-dependent manner, which can impact sexual behavior and brain activity. The user experienced significant hair regrowth and side effects on 1mg of finasteride, which diminished after reducing the dose to 0.5mg, leading to no side effects and further hair improvement.

      community Anyone else a non-responder to spiro?

      in Treatments  63 upvotes 2 years ago
      The conversation discusses hair loss treatments, specifically mentioning Spiro, Min, Fin, and RU. It highlights that Spiro is generally for women and can affect men's hormonal balance.

      community Found a slide summary for PP405

      in Research/Science  33 upvotes 3 months ago
      PP405 shows promise in stimulating new terminal hair growth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.

      community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

      in Treatment  13 upvotes 6 years ago
      PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

      community CB-03-01 supposed hair loss cure

      in Treatment  9 upvotes 5 years ago
      The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

      community NMN supplementation experiences?

      in Research/Science  2 upvotes 6 months ago
      The conversation discusses experiences with NMN supplementation for hair growth, with some users reporting increased hair growth activity and others seeing no significant changes. OP has been using dutasteride and oral minoxidil, and recently added NMN, noticing increased shedding, which they hope indicates new hair growth.

      community HT scheduled. Am I over reacting?

      in Transplants  13 upvotes 1 year ago
      The user has scheduled a hair transplant after stabilizing hair loss with finasteride and minoxidil, considering additional dermarolling. They are advised to use 2500-3000 grafts conservatively for temple filling without lowering the hairline too much.

      community IGE Hair Loss and Miniaturization

      in Chat  3 upvotes 1 year ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

      community How an SSRI seemed to help my hairloss

      in Chat  7 upvotes 3 years ago
      An SSRI (paroxetine) reduced hair loss and itching for a user with male-pattern baldness, but liver issues forced discontinuation, leading to increased hair loss and anxiety. The user plans to try other anti-anxiety medications, noting stress and anxiety significantly impact hair loss.

      community What the hell happened in my family genes?

      in Chat  116 upvotes 2 years ago
      A user is frustrated about early balding despite older male relatives retaining hair into old age. Another user plans to start finasteride soon to address their hair thinning.

      community Non-Responder to everything and currently at the lowest point in my life

      in Update  60 upvotes 4 years ago
      A user expressed frustration with hair loss treatments, including finasteride, minoxidil with micro-needling, and RU58841, which all failed to stop hair thinning and miniaturization. Suggestions from others included accepting baldness, considering hair systems, and continuing prescribed antidepressants for depression.

      community Is anyone on topical NMN 1% here?

      in Research/Science  1 upvotes 2 years ago
      A user added 1% NMN to their 5% minoxidil mix for hair loss, which also includes melatonin, ginkgo, nettle root, and plans to add caffeine. They are asking if anyone has tried topical NMN for hair growth.

      community TresslessGPT is available to ChatGPT Plus users

      in 📣 Announcement  107 upvotes 2 years ago
      The conversation introduces a specialized chatbot for ChatGPT Plus users that provides advice on hair loss treatments, drawing from research and community insights. It mentions treatments like RU58841, the "big 4" (likely minoxidil, finasteride, ketoconazole, and tretinoin), dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

      community AHK vs GHK for hair growth in the crown area?

      in Product  2 upvotes 3 months ago
      AHK and GHK are discussed for hair growth in the crown area, with questions about side effects and safety after microneedling. Users share experiences and concerns about these treatments.

      community My "natural" hair care regimen--will keep updates

       4 upvotes 7 years ago
      A 25-year-old is experiencing mild hair loss and is using a regimen including scalp brushing, dermarolling, topical minoxidil, caffeine, melatonin, and a DHT-blocking shampoo. Another person shares their struggle with hair loss due to drug use and plans to start finasteride while trying to quit drugs.