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GlossaryAutosomal Recessive Woolly Hair

genetic condition causing tightly curled, wool-like hair

Autosomal Recessive Woolly Hair is a genetic condition characterized by tightly curled, wool-like hair that is inherited in an autosomal recessive pattern. This means that an individual must inherit two copies of the mutated gene, one from each parent, to exhibit the trait. The condition is often associated with mutations in specific genes such as LIPH or LPAR6, which are involved in hair follicle development and function.

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community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

in Research/Science 26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community Pirfenidone - The answer to fibrosis and baldness

in Treatment 19 upvotes 4 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

community Woolly mice but no hair growth treatment for humans yet 🤷‍♂️

in Technology 225 upvotes 1 year ago

Hair regrowth treatments are effective in mice but not yet available for humans. The discussion humorously highlights frustration over this disparity and mentions a project to genetically modify elephants to resemble mammoths.

community Korean scientists breakthrough in hair regeneration targeting CXXC5 protein and WNT Signaling Pathway

54 upvotes 8 years ago

A potential non-invasive topical treatment targeting the WNT Signaling Pathway for hair regeneration is being researched, with positive results on human hair follicle cells. Current effective treatments for hair loss include Minoxidil, finasteride, and hair transplantation.

community Hair loss and ethnicity - Caucasian men the most likely to experience hair loss

in Chat 17 upvotes 3 years ago

The conversation discusses how Caucasian men are more likely to experience hair loss due to genetic predisposition, with factors like the androgen receptor on the X chromosome playing a significant role. The user also expresses confusion about the evolutionary reasons for hair loss, especially in colder climates where it would seem beneficial to retain hair for warmth.

community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 8 months ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

community Fuzzy weird hair in the front, seasonal shedding

4 upvotes 7 years ago

A 22-year-old is experiencing hair loss, particularly fuzzy hair in the front, and is concerned about male pattern baldness. Treatments mentioned include Propecia (finasteride), minoxidil, PRP treatments, dermarolling, peppermint oil, and apple cider vinegar.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 50 upvotes 1 year ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Anyone else got the short, curly and wiry beard-like hair above and behind the ears?

6 upvotes 12 years ago

The conversation discusses a user experiencing short, curly, wiry hair above and behind the ears, linking it to pattern baldness. The user suggests starting treatment early but personally chose not to pursue treatments like Minoxidil, finasteride, or RU58841 due to the hassle.

community Another blow to the cursed baldness

in Research/Science 91 upvotes 8 months ago

A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.

community Naturally mummified remains found in the coast of Chile around 7020 BC. Still has more hair than everyone on this sub

in Satire 2042 upvotes 5 years ago

Hair loss treatments, including finasteride and RU58841, with humorous speculation about the cause of death for an ancient mummy that still had hair.

community norwood 7 from both sides of family, destined to go bald 17M

in Chat 9 upvotes 3 years ago

17M approaching Norwood 2, using topical minoxidil and considering finasteride, oral minoxidil, and pyrilutamide. Plans to study dermatology and possibly get a hair transplant at 25 if treatments don't work.

community Shedding hair like crazy idk why

in Chat 4 upvotes 2 years ago

An 18-year-old male is experiencing significant hair shedding, particularly from the back of his head, despite normal blood test results except for slightly low vitamin D. A dermatologist prescribed minoxidil for receding temples, but the cause of the shedding remains unclear.

community Genetics are so weird and unpredictable

in Minoxidil 118 upvotes 1 year ago

The user experienced male pattern baldness starting at 18, tried finasteride with no success, and switched to dutasteride, which halted hair loss. Minoxidil had no effect for them, while their brother, who didn't use AR inhibitors, maintained a juvenile hairline and successfully grew a beard with minoxidil, highlighting the unpredictable nature of genetics in hair loss and treatment response.

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 2 years ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

community r/tressless members when encountering people with good hair genetics

in Satire 290 upvotes 3 years ago

Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. Users share experiences and support, mentioning that many people face hair thinning.

community Welcome to Tressless, OG! Ötzi was dark-skinned and balding.

in Chat 11 upvotes 2 years ago

The conversation discusses that genetic analysis of the Iceman Ötzi shows he had male-pattern baldness and dark skin, with a joke about using beards and tattoos to distract from hair loss. No specific hair loss treatments are mentioned.

community Sustaining minoxidil dependent hairs?

in Research/Science 9 upvotes 2 years ago

Minoxidil-dependent hairs fall out if minoxidil is stopped. New treatments like GT20029, FOL055, or TDM105795 might help sustain these hairs.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 3 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community I want to sacrifice my hair in the name of science

in Chat 12 upvotes 2 years ago

The conversation discusses various theories of hair loss, including DHT sensitivity and genetic factors, with the user willing to use themselves for research due to having a hair loss gene but different hair loss patterns compared to their brothers. Specific treatments were not mentioned in the provided text.

community Chromosome 20’s balding effects and why fin likely isn’t working for some.

in Treatment 96 upvotes 8 months ago

Finasteride is effective for DHT/AR-driven hair loss but not for chromosome 20-driven cases, where treatments like minoxidil, prostaglandin analogs, and low-level laser therapy may be more beneficial. Genetic testing can help determine the underlying cause of hair loss to tailor treatment effectively.

community I’ve always lacked a patch of hair, can it be fixed?

in General 36 upvotes 1 year ago

The conversation discusses a small patch of missing hair and whether treatments like Minoxidil, finasteride, or RU58841 could help. The user is seeking advice on addressing this specific hair issue.

community If all these vellus hairs turn terminal I’m gonna be a chewbacca

in Is this regrowth? 91 upvotes 3 months ago

The user is using minoxidil, finasteride, dermarolling, and other treatments for hair regrowth, showing promising results in the temple area. Despite some skepticism, there is optimism about potential improvement.

community Losing the genetic lottery - venting

in Chat 67 upvotes 1 month ago

The user is experiencing hair loss and has tried various treatments including topical and oral finasteride, minoxidil, dutasteride, and ketoconazole, but continues to lose hair. They are considering alternative solutions like hair systems due to the lack of improvement and a scalp condition called CVG.

community Does My Grandfather Being Bald Mean I'm F***ed?

in Advice 4 upvotes 8 years ago

Hair loss is influenced by multiple genetic factors, not just maternal lineage. Treatments like finasteride, minoxidil, and nizoral are suggested if male pattern baldness progresses.