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      community Azelaic acid with ru58841 combination

      in Treatment 2 months ago
      The conversation discusses using azelaic acid to reduce scalp inflammation while using RU58841 for hair loss. It suggests applying azelaic acid in the morning and RU58841 at night to avoid degradation, while also using dutasteride and minoxidil.

      community How exactly is Eucapil (fluridil) approved in Europe?

      in Product  6 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. Eucapil (fluridil) is approved as a cosmetic hair-care agent in Europe, but users question the level of testing required for approval.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Dutasteride and it’s effect on Erections

      in General  105 upvotes 9 months ago
      The user switched from finasteride to dutasteride and initially experienced increased energy and libido but is now facing erection issues. They are unsure if it's due to performance anxiety and are seeking advice while wanting to continue dutasteride for its benefits.

      community Bicalutamide effect on androgens?

      in Treatment  5 upvotes 5 years ago
      Bicalutamide blocks androgen receptors, preventing testosterone and DHT from binding, which can help with hair loss but may cause feminization. It is not recommended for those who do not want feminization effects.

      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  13 upvotes 4 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community Zyrtec (Cetirizine) antihistamine for hair growth compared to Minoxidil NIH study

      in Minoxidil  35 upvotes 3 years ago
      The conversation discusses the potential of topical cetirizine (Zyrtec) for hair growth in comparison to minoxidil, noting cetirizine's ability to reduce prostaglandin D2, which inhibits hair growth. Users share mixed experiences with cetirizine for allergies and scalp health, and there's a mention of the risk of dementia with long-term antihistamine use.

      community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

      in Research/Science  1 upvotes 1 week ago
      AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

      community My good/bad experience with Creatine

      in Treatment  30 upvotes 11 months ago
      Creatine may cause increased hair shedding in some individuals, especially those with androgenetic alopecia (AGA), despite its physical performance benefits. Many users report stopping creatine to reduce hair loss, while others believe the effects are anecdotal or due to other factors like increased physical activity.

      community Something that helped my Fin sides massively (ED).

       4 upvotes 12 years ago
      Taking 1000mg l-arginine alongside 0.5 mg finasteride every other day helped alleviate erectile dysfunction and possibly increased libido. The user recommends trying l-arginine for those experiencing sexual side effects from finasteride.

      community The mystery of Azelaic Acid

       5 upvotes 10 years ago
      The conversation discusses using Rogaine (Minoxidil) and ketoconazole for hair regrowth, with interest in trying a formulation with Azelaic Acid for potentially better results. Concerns about Azelaic Acid's effectiveness and safety, including skin sensitivity to sunburn, are mentioned.
      Last Attempt at Fighting The Curse

      community Last Attempt at Fighting The Curse

      in General  210 upvotes 4 months ago
      The user is using minoxidil, finasteride, dutasteride, and clobetasol, along with needling, to combat hair loss. They are considering stopping treatment if no improvement is seen.

      community Pyrilutamide from Hairlisciously? Other suppliers?

      in Treatment  8 upvotes 3 years ago
      The conversation is about the effectiveness and trustworthiness of Pyrilutamide hair loss treatment sold by Hairlisciously, with concerns about product purity and a request for alternative suppliers. No specific treatments were confirmed to be used by participants.

      community formula 82D for diffuse androgenic alopecia (DUPA)

      in Is this regrowth?  17 upvotes 1 year ago
      The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.

      community My summation of PP405 - looks promising

      in Research/Science  208 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community 5.5 month progress - 3500 grafts- WSC clinic Istanbul

      in Progress Pictures  13 upvotes 2 years ago
      A user underwent a hair transplant with 3500 grafts at WSC clinic in Istanbul and uses finasteride, biotin, multivitamins, minoxidil with finasteride, biotin shampoo, and coconut oil with peppermint oil for hair loss treatment. Another user commented that the result looks like a barren patch of hair.

      community Annurca Nutraceutical and hair

       17 upvotes 8 years ago
      Apple core extract pills, believed to enhance hair density, are discussed as a potential treatment for hair loss. Users express cautious optimism and interest in trying the product, while acknowledging skepticism and the high cost.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  120 upvotes 5 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community Is there a difference in Fin brands ?

      in Finasteride/Dutasteride  4 upvotes 2 years ago
      Switching from Accord to Aurobindo finasteride initially reduced hair shedding, but after three months, shedding increased again. Users discuss varying experiences with different finasteride brands, with some suggesting brand differences may not matter.

      community Joining clinical study for Clascoterone (Breezula)

      in Research/Science  7 upvotes 1 year ago
      The conversation is about a user considering joining a clinical study for Clascoterone (Breezula) after experiencing no results with topical finasteride and minoxidil, and side effects from oral finasteride. The user is seeking advice on clinical study participation and experiences.