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      community Extreme caution: my experience using Ru58841 only once

      in Treatment  10 upvotes 1 year ago
      An 18-year-old experienced severe side effects, including heart palpitations and high blood pressure, after using RU58841 once, leading to a referral to cardiology for suspected left ventricular hypertrophy. The user regrets using RU58841 and seeks advice on recovery, while others suggest preexisting conditions or genetic predispositions may be factors.

      community 4 months on dut and topical min as a 23 year old

      in Progress Pictures  76 upvotes 1 year ago
      A 23-year-old shares progress in hair quality after 4 months using dutasteride, topical minoxidil, and other treatments, noting improved crown thickness but persistent temple thinning. They switched from finasteride to dutasteride due to side effects and started testosterone replacement therapy, which they believe helps mitigate side effects.

      community Bryan Johnson and his Hair routine, what's the point?

      in Hair Systems  24 upvotes 2 months ago
      Dutasteride and high-dose Minoxidil are the primary treatments maintaining hair, with additional supplements and therapies like red light offering minimal extra benefit. The discussion criticizes promoting expensive hair care products when basic medications are doing most of the work.

      community Can HMI-115 reverse miniaturization?

      in Research/Science  12 upvotes 3 years ago
      HMI-115, a potential treatment for hair loss that can reverse miniaturization and make individual hairs thicker, as evidenced by data from macaques given the treatment and one subject in the phase I trial.

      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes 4 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

      community Where is GT20029 already? Grrrr

      in Research/Science  20 upvotes 2 years ago
      The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.

      community Clascoterone for hair loss. Promising study.

      in Treatment  12 upvotes 6 months ago
      A new topical medication, Clascoterone, shows promise for hair loss, improving hair count significantly. Trials for Breezula are ending, but sign-ups for PP405 trials are available for 2026.

      community 5 months since I became obsessed with my hair

      in Is this regrowth? 7 months ago
      The user is experiencing hair regrowth and increased hair thickness after using supplements like biotin, zinc, selenium, and a complex with various natural ingredients, along with topical caffeine. They are considering using topical minoxidil and mesotherapy in the future.

      community what is the problem with straight low hairline? Hair transplant question

      in Transplants  8 upvotes 9 months ago
      The user is concerned about having a straight, low hairline after a hair transplant and is unable to take finasteride due to high estrogen and prolactin levels. They have used minoxidil with limited success and are considering further transplants to lower the hairline, while others suggest the risks of using up donor hair too quickly.

      community Debunking Androgenetic Theory (Hair Transplants)

      in Research/Science  25 upvotes 2 years ago
      The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

      community Huge holes on donor area of scalp is this even normal?

      in Transplants  106 upvotes 2 years ago
      The conversation is about a person experiencing significant hair loss in the donor area after a hair transplant, with others suggesting it might be shock loss. The person is taking oral minoxidil and dutasteride to help with the issue.

      community Justin Bieber hair loss new photos update

      in Chat  594 upvotes 2 years ago
      The conversation suggests Justin Bieber has had a hair transplant, with many users agreeing on the change in his hairline and discussing the commonality of hair loss and transplants among men, including celebrities. Some speculate he might also be using hair loss medications like minoxidil and finasteride.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2446 upvotes 5 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community Non responsive diffuse thinning

      in Progress Pictures  9 upvotes 8 months ago
      The user has been experiencing diffuse hair thinning despite using finasteride, minoxidil, dermarolling, clobetasol cream, and PRP sessions. They seek advice on additional treatments and are advised to check vitamin D, iron, and thyroid levels.

      community FTM/NB Hairloss from HRT, treatment started and feeling hopeless.

      in Transgender  61 upvotes 1 year ago
      A non-binary individual experienced hair loss after stopping hormone replacement therapy and is using oral Dutasteride, oral Minoxidil, and ketoconazole shampoo. They are hopeful for regrowth but may use wigs due to the high cost and uncertain effectiveness of additional treatments like mesotherapy and PRP.

      community The Theory of BURN THE SCALP. !! PHOTOS ¡¡

      in Update  13 upvotes 1 year ago
      The conversation discusses a user's experiment of "burning the scalp" to treat hair loss, with mixed opinions on its effectiveness. Some suggest returning to proven treatments like finasteride and minoxidil, while others note slight improvements in hair density.

      community A theory about "embracing" the bald look

      in Chat  173 upvotes 6 months ago
      Baldness and modern fashion trends, with a focus on shaving heads and using treatments like minoxidil to manage hair loss and enhance appearance.

      community My endless RU58841 cycle [experience thread)

      in Update  10 upvotes 1 year ago
      The user experienced hair loss and itching after stopping RU58841 and resumed it to stop these symptoms. They also use Dutasteride and question which treatment is effective.

      community Exploring all options - Scalp tension theory

      in Research/Science  13 upvotes 1 year ago
      The conversation discusses the scalp tension theory as a potential factor in hair loss, alongside DHT, inflammation, and other mechanisms. Treatments mentioned include finasteride, minoxidil, and botox injections, with some users exploring additional methods due to varying effectiveness.