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GlossaryBenzimidazole

organic compound with antifungal and antiparasitic properties

Benzimidazole is a type of organic compound that consists of a fusion between benzene and imidazole rings. It is commonly used in pharmaceuticals for its antifungal and antiparasitic properties, making it effective in treating infections and certain types of worms. Additionally, benzimidazole derivatives are being researched for their potential in cancer treatment and other medical applications.

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community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)

in Research/Science 17 upvotes 3 years ago

Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.

community Pyrludimide (KX-826) or Breezula (clascoterone)

in Treatment 9 upvotes 2 months ago

The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

community Pyrilutamide Phase 3 on its way

in Treatment 128 upvotes 4 years ago

Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.

community I'm very skeptical about pyrilutamide

in Product 2 upvotes 3 months ago

Pyrilutamide's effectiveness is questioned due to overstated claims and previous trial ineffectiveness, with some users opting for finasteride instead. Despite skepticism, some consider adding pyrilutamide to their regimen alongside treatments like bicalutamide.

community Best carrier for pyrilutamide?

in Update 9 upvotes 3 years ago

The conversation is about adding a low dose of pyrilutamide to a hair loss treatment regimen. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community Has anyone seen this study before? It claims that B6+Zinc can inhibit 5ar activity

in Technology 77 upvotes 3 years ago

The conversation discusses using B6 and Zinc to inhibit 5ar activity, similar to Fin and Dut. Minoxidil is mentioned as a supplementary treatment.

community So Pyrilutamide has been postponed by one year. How likely is that to happen to GT20029

in Treatment 27 upvotes 2 years ago

The conversation discusses the delay in the release of a new hair loss treatment, Pyrilutamide, and speculates on potential safety concerns as a reason for the delay. It also mentions GT20029 as another future treatment option, with a release at least five years away, and touches on the avoidance of research chemicals due to uncertainty about their authenticity.

community Pyrilutamide binding affinity is similar to RU

in Research/Science 16 upvotes 3 years ago

Comparing the effectiveness of RU58841, Pyrilutamide and CB-03-01 as treatments for hair loss, with people discussing different aspects such as binding affinity, time of inhibition, safety data and cost.

community Pyrilutamide or RU or cb-03-01?

in Minoxidil 2 upvotes 6 months ago

The conversation discusses using Minoxidil, finasteride, RU58841, and pyrilutamide for hair loss treatment. The user is considering adding a topical treatment and has not experienced side effects from current treatments.

community Doctors won't let me try bicalutamide or fin

in Female 6 upvotes 5 years ago

Hair loss treatments discussed include 200mg Spiro, bicalutamide, and finasteride. Endocrinologist advises against bicalutamide and finasteride due to potency and risks.

community What happened to Pyrilutamide?

in Technology 1 upvotes 1 year ago

Pyrilutamide's 0.5% solution showed minimal improvement, while the 1% solution appears more promising but costly. The user is currently using finasteride and oral minoxidil and considering adding Pyrilutamide if effective and affordable.

community Pyrilutamide is literally my only hope

in Chat 91 upvotes 3 years ago

Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.

community Pyrilutamide 0.5 or 0.025% topical fin for maintaining?

in Basic Questions 91 upvotes 1 month ago

The user is considering switching from pyrilutamide to 0.025% topical finasteride due to concerns about effectiveness and past side effects from a scalp elixir. They aim to maintain hair until new treatments like breezula or GT00029 become available.

community pyrilutamide solution progress log

in Product 20 upvotes 3 years ago

A 28 year old using a hair loss prevention protocol to restore thinning hair, which includes finasteride, dutasteride, minoxidil, stemoxydine, alopecin, nizoral shampoo and microneedling; the user is now adding pyrilutamide solution to the regimen with the hope of improving their results. RU58841 was also ordered but not yet used.

community Pyrilutamide release in Europe?

in Treatment 2 upvotes 3 years ago

User asks about Pyrilutamide release in Europe, specifically Germany, and considers importing it from China. No specific treatments mentioned.

community Pyrilutamide available at Actifolic now

in Research/Science 15 upvotes 3 years ago

Pyrilutamide, a new hair loss product with the potential to be more effective than RU58841 and safer than CB, but expensive.

community pyrilutamide GB update please? Anything no matter how big or small

in Update 34 upvotes 4 years ago

The effects of Finasteride on hair loss and its side-effects, such as aching balls. The user has been taking it for two years with no changes to the symptom.

community Pyrilutamide is available at Minoxidilmax

in Research/Science 58 upvotes 3 years ago

Minoxidilmax offering a 0.5% Pyrilutamide solution and debating the cost, effectiveness, and safety of using it alone or with other treatments such as Finasteride and Minoxidil.

community Where the fuck are the pyrilutamide GB guys?

in Chat 23 upvotes 4 years ago

The effects of Pyrilutamide, a hair loss treatment that is being tested for June/July; and reports from people who have experienced side effects similar to those of RU58841, suggesting they may have been sold an incorrect product from their supplier.

community HMI-115: What We Know So Far. HMI-115 (also known as BAY1158061) is a new pharmaceutical drug developed by a biopharmaceutical company called Bioinvent and licensed by Bayer

in Research/Science 51 upvotes 2 years ago

HMI-115 is a new drug developed by Bioinvent and licensed by Bayer, with mixed opinions on its potential effectiveness. Some users are skeptical and prefer proven treatments like Minoxidil, finasteride, and RU58841.

community Bicalutamide effect on androgens?

in Treatment 4 upvotes 5 years ago

Bicalutamide blocks androgen receptors, preventing testosterone and DHT from binding, which can help with hair loss but may cause feminization. It is not recommended for those who do not want feminization effects.

community Clascoterone/ Breezula will it work

in Research/Science 2 months ago

Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.

community The New, Improved CB-03-01/Setipiprant Group Buy

27 upvotes 9 years ago

The group buy for CB-03-01, a topical anti-androgen for hair loss, was postponed and refunded due to issues with the product's form and solubility. The product, also known as Breezula, is an alternative to finasteride with fewer side effects, but its official release is delayed until 2021.

community For those of you applying Pyrilutamide, what's your plan B?

in Treatment 6 upvotes 2 years ago

The user switched from Pyrilutamide to RU58841, changed their Minoxidil solution, and continued using low-dose Finasteride, derma rolling, and specific shampoo. They asked others about their plans after Pyrilutamide's disappointing results.

community Breezula hasn't even begun phase 3 trials yet. F*cking hell.

in Treatment 44 upvotes 4 years ago

The conversation is about the delay in Breezula's phase 3 trials and skepticism regarding its effectiveness compared to other treatments like RU58841 and Pyrilutamide. Some users prefer safety over effectiveness, while others express frustration with the slow progress and doubt Breezula will be a significant treatment for hair loss.

community thoughts on Pyrilutamide early use?

in Treatment 17 upvotes 4 years ago

User asks about Pyrilutamide for hair loss and its cost. Questions include legitimacy of selleckchem, vehicle to use, and storage.

community pyrilutamide – did anybody had any success on it?

in Finasteride/Dutasteride 15 upvotes 3 years ago

Potential success with the hair loss treatment Pyrilutamide, and possible group buying opportunities for it along with other treatments such as Finasteride and Minoxidil.

community Pyrilutamide should not be mixed with Minoxidil?

in Product 6 upvotes 3 years ago

Pyrilutamide should not be mixed with Minoxidil because the water in Minoxidil can degrade it. It's suggested to apply Minoxidil first, wait an hour, then apply Pyrilutamide.

community Beeezula off label (winlevi compounded)

in Treatment 7 upvotes 4 years ago

User seeks availability of Breezula and its delayed trials. Asks for success with similar topical antiandrogens like fluridil.

community CB-03-01 / Breezula Personal Results

in Treatment 17 upvotes 4 months ago

The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.