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      community Efficacy of Dut at 0.5mg VS 1mg VS 2.5mg

      in Finasteride/Dutasteride  49 upvotes 1 year ago
      Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.

      community Dutasteride mesotherapy to lower dut dose

      in Finasteride/Dutasteride  1 upvotes 9 months ago
      The conversation is about a user considering reducing their dutasteride dose due to side effects like lower libido and watery semen. They plan to use dutasteride mesotherapy every three months to maintain hair while reducing systemic DHT suppression.

      community Painkillers May Block Minoxidil

      in Research/Science  14 upvotes 1 year ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community Similar 5ar inhibitors to fin?

      in Finasteride/Dutasteride 4 years ago
      Natural vitamins like pumpkin seed oil, saw palmetto, and ecklonia cava are discussed for their potential to lower DHT levels. They may work similarly to finasteride but are significantly weaker.

      community Early Signs - Notes for diffuse thinners

      in Treatment  11 upvotes 4 months ago
      Diffuse thinning is often due to androgenetic alopecia, and DHT blockers like finasteride are recommended. Treatments mentioned include minoxidil, finasteride, dutasteride, and RU58841, with emphasis on starting early and using a holistic approach.

      community Question about solution to pill conversion

      in General  67 upvotes 1 year ago
      The user left their 2.5 mg pills at home and is considering using 5% topical minoxidil as a substitute. They also inquire about where to obtain over-the-counter minoxidil pills.

      community (Serious) Updates and discussion, new treatments in development

      in Treatment  7 upvotes 1 year ago
      Finasteride, minoxidil, and derma rolling are currently the best treatments for hair loss. New treatments like TDM-105795, GT20029, PP405, HMI 115, Tsuji, Scube 3, RU, JW0061, Topilutamide, and verteporfin show promise but have uncertain timelines.

      community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

       22 upvotes 8 years ago
      Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.

      community 4 months progress at oral fin and oral minoxidil

      in Treatment  25 upvotes 1 year ago
      The user reported progress in hair growth after 4 months using 0.5 mg finasteride and 2.5 mg minoxidil daily, and is considering adding RU58841 to block DHT on the scalp. They experienced side effects like reduced libido and mild erectile dysfunction, and take supplements like zinc, iron, fish oil, vitamin D, magnesium, and vitamin E.

      community 3 months oral Minox 1.25 mg topical fin .1 %

      in Is this regrowth?  95 upvotes 1 year ago
      A 27-year-old male has been using oral minoxidil and topical finasteride for 3 months, noticing fuller, thicker hair with no side effects. Users discuss the effectiveness and side effects of oral versus topical treatments, with some recommending higher doses or additional treatments like topical minoxidil.

      community How to make topical melatonin?

      in Treatment  1 upvotes 2 years ago
      The conversation is about creating a topical melatonin treatment for hair loss. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.

      community Switching from topical min to oral min. Is it the right choice?

      in General  97 upvotes 6 months ago
      The user is considering switching from topical minoxidil to a combined oral treatment of finasteride and minoxidil for better consistency but is concerned about potential side effects like shedding, dizziness, and swelling. Another user advises that oral minoxidil should only be used under medical supervision with regular health checks and suggests using reputable brands like Pfizer's Loniten.

      community Anyone read oral minoxidil's leaflet?

      in Minoxidil  4 upvotes 1 year ago
      Oral minoxidil is discussed, highlighting potential cardiovascular risks at high doses, but users note that lower doses commonly used for hair loss are generally considered safe. Monitoring by doctors is advised, and some users report taking it without issues, comparing its risks to those of common medications like ibuprofen.

      community 4 month progress .5mg dut + 2.5mg min

      in Is this regrowth?  102 upvotes 3 months ago
      A user shared their 4-month hair regrowth progress using 0.5mg dutasteride and 2.5mg minoxidil, reporting no side effects and significant improvement. The conversation includes discussions on treatment choices, dosages, and personal experiences with hair loss treatments.

      community A scary individual report of RU58841.

      in Research/Science  33 upvotes 1 year ago
      RU58841 caused severe side effects like heart palpitations and shortness of breath, leading the user to stop using it. Minoxidil and finasteride were effective without side effects, while RU58841's safety and effectiveness remain uncertain.

      community Anagenic is trying to compound Gt20029

      in Treatment  56 upvotes 3 years ago
      The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

      community the ordinary retinol & minoxidil

      in Minoxidil  13 upvotes 1 year ago
      Using retinol with minoxidil may not be as effective as tretinoin, but retinaldehyde or adapalene could be alternatives. A micro-roller with minoxidil is suggested for better results.

      community 4 months on 2.5 mg OM, no improvement

      in Minoxidil  6 upvotes 3 years ago
      After 4 months on oral minoxidil with no significant hair regrowth, a user is frustrated and considering alternative treatments since they can't take finasteride due to side effects. Suggestions include natural DHT blockers, lifestyle changes, and other hair care tips.