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      community tretinoin cream concentration question

      in Treatment  12 upvotes 3 years ago
      The conversation is about choosing the right concentration of tretinoin cream to enhance the absorption of minoxidil for hair loss treatment. The options discussed are 0.5, 0.05, 0.25, and 1mg/g concentrations.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  51 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Clascoterone - Why are there so few posts if it’s already on the market?

      in Chat  34 upvotes 3 months ago
      Clascoterone is being discussed for hair loss, but its current acne formulation may not be suitable for scalp use due to potential skin irritation and lower dosage compared to Breezula. Users mention other treatments like finasteride, minoxidil, and pyrilutamide, with some expressing skepticism about clascoterone's effectiveness for hair loss.

      community M22 Almost 3 months into treatment

      in Progress Pictures  131 upvotes 4 months ago
      A user shared progress pictures after almost 3 months of using dutasteride, minoxidil, stemoxydine, and tretinoin for hair loss, reporting positive results and no significant side effects. The user chose dutasteride over finasteride due to early balding and noted benefits like better skin and increased libido.

      community Approach: starting with dut then came om finestride

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      The user initially used dutasteride, minoxidil, and vitamins, then switched to finasteride but experienced side effects and hair loss. They found better results with a natural supplement containing stinging nettle and beta-sitosterol, reporting thicker hair without side effects.

      community A vehicle for powdered melatonin

      in Treatment  7 upvotes 4 years ago
      The conversation is about using topical melatonin for hair loss and seeking advice on a safe mixing solution or pre-mixed product. Specific treatments mentioned are minoxidil, finasteride, and RU58841.

      community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound

      in Research/Science  130 upvotes 3 years ago
      The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.

      community Any other treatments to still be hopeful for?

      in Research/Science  20 upvotes 2 years ago
      The conversation discusses the potential of new hair loss treatments, with a focus on pyrilutamide, gt20029, and topical alfatradiol, and the possibility of improving their effectiveness through methods like increased concentration and microneedling. Dutasteride is also mentioned as a stronger option.

      community Has anyone tried latanoprost+microneedle?

      in Microneedling  2 upvotes 2 years ago
      Microneedling combined with latanoprost may convert vellus hairs to transitional or terminal hairs. The user suggests using oral minoxidil to increase vellus hair, then applying a high concentration of latanoprost with microneedling for conversion.

      community Tretinoin, any good, what’s your experience

      in Research/Science  21 upvotes 1 year ago
      The conversation discusses using tretinoin for hair loss and skincare. Users share experiences, noting tretinoin's effectiveness in combination with minoxidil for hair and its proven benefits for anti-aging skincare.

      community Is Retinol effective by itself?

      in Treatment  3 upvotes 8 months ago
      Retinol is not effective alone for hair loss; tretinoin is more potent and sometimes mixed with minoxidil. Retinoids do not stop hair loss, and finasteride or dutasteride is necessary for that.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 8 months ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community CB-03-01 supposed hair loss cure

      in Treatment  9 upvotes 5 years ago
      The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

      community Alfatradiol to combat hair loss

       5 upvotes 12 years ago
      Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Alfatradiol is suggested as another potential solution.

      community Can tretinoin cause problems or issues with min?

      in Minoxidil  2 upvotes 1 year ago
      The user is using a topical routine of finasteride and minoxidil, noticing increased hair growth, and is considering adding tretinoin for skin issues. Tretinoin may enhance minoxidil's effectiveness, but care should be taken to allow proper absorption to avoid unintended facial hair growth.

      community New to tretinoin, when to apply?

      in Minoxidil  2 upvotes 3 months ago
      The conversation is about using tretinoin to enhance the effectiveness of minoxidil for hair loss. Tretinoin should be applied at night on dry skin, and it can be used daily, either before or after minoxidil, with a starting dose of 0.025%.

      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

      in Research/Science  218 upvotes 10 months ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community Blood test and low vitamine D what now ?

      in Treatment  2 upvotes 2 years ago
      A 20-year-old with thinning hair has low vitamin D and normal testosterone. They are prescribed oral minoxidil and vitamin D, and are questioning if finasteride is also necessary.

      community Chat is this real? Compound called clascoterone

      in Research/Science  585 upvotes 4 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community My dermatologist gave me Ell cranell?

      in Treatment  4 upvotes 2 years ago
      The user is seeking advice on a hair loss treatment called Ell Cranell, which contains Alfatradiol. Another user shared information from a study stating that Alfatradiol only slows down or stabilizes hair loss, but does not increase hair density or thickness.

      community How long are Pelage going to milk the phase 2a results of PP405?

      in Chat  21 upvotes 3 months ago
      PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.