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      community Is microneedling really that effective?

      in Microneedling  35 upvotes 10 months ago
      Microneedling's effectiveness for hair growth is debated, with some users reporting positive results when combined with minoxidil and finasteride, while others experienced scarring and no benefits. Needle depth and frequency vary, with some suggesting 0.5-1mm as effective, but caution is advised to avoid overuse and potential harm.

      community Let’s get PP405 trending on Twitter!

      in Chat  69 upvotes 11 months ago
      People are excited about a new hair loss treatment, PP405, and some suggest using Twitter to increase its visibility. Current treatments mentioned include finasteride, minoxidil, and dutasteride, but skepticism remains about the effectiveness of new treatments.

      community What do you think about this study?

      in Product  112 upvotes 11 months ago
      The conversation discusses skepticism about new hair loss treatments, with many users expressing doubt about the effectiveness and availability of future solutions. Current treatments like minoxidil, finasteride, and hair transplants are mentioned as reliable options.

      community Why is it so hard to select one

      in Satire  645 upvotes 1 year ago
      Choosing hair loss treatments is challenging due to concerns about side effects from finasteride and minoxidil. Users suggest starting with topical treatments and gradually increasing dosage, while some recommend oral finasteride for its effectiveness despite potential side effects.

      community Breaking hair loss news! GT20029 is a resounding success!

      in Product  132 upvotes 2 years ago
      GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  444 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Do you think clascoterone is overhyped

      in Treatment  14 upvotes 1 month ago
      Clascoterone is considered overhyped and not as effective as finasteride or dutasteride, but it may be useful as a supportive treatment in combination with other therapies. Users express skepticism about its effectiveness compared to clinical trials, with some suggesting it could be beneficial for those who cannot tolerate other treatments.

      community Breezula is a good alternative

      in Research/Science  5 upvotes 1 month ago
      Clascoterone 5% solution (Breezula) is a promising alternative for androgenetic alopecia, showing continued hair growth with consistent use and no significant side effects. It may be suitable for those who cannot tolerate finasteride or dutasteride, especially when trying to conceive.

      community Pp405 - it has to work. It has to.

      in Research/Science  170 upvotes 3 months ago
      Hair loss treatments, including PP405, minoxidil, finasteride, and RU58841, with hopes for future solutions. Participants discuss the emotional impact of hair loss and consider alternatives like hair transplants or acceptance.

      community Chat is this real? Compound called clascoterone

      in Research/Science  588 upvotes 6 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community How would you react if PP405 isn't successful in phase 3 trials?

      in Chat  23 upvotes 6 months ago
      People are discussing their reactions if PP405 fails in phase 3 trials, with some expressing skepticism and others holding onto hope for future treatments like GT20029 and Breezula. Many mention continuing with existing treatments like minoxidil and finasteride, while others express disappointment and consider alternative solutions.

      community Long Term Dutasteride experiences wanted!

      in Finasteride/Dutasteride  26 upvotes 6 months ago
      Users discuss their experiences with dutasteride for hair loss, noting varying results such as regrowth, shedding, and side effects. Some users also mention using finasteride, minoxidil, and microneedling, with mixed outcomes on hair quality and side effects.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  122 upvotes 7 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community M30, month 5 of dutasteride and minoxidil

      in Progress Pictures  250 upvotes 8 months ago
      A 30-year-old male experienced significant hair regrowth after five months of using topical minoxidil (5% foam) and oral dutasteride (0.5 mg daily). The user reported no side effects and was grateful for the progress, despite the rapid gains slowing down.

      community Topical finasteride vs oral Dutasteride?

      in Finasteride/Dutasteride  7 upvotes 9 months ago
      Oral Dutasteride and topical Finasteride may have similar effects on scalp DHT, but topical Dutasteride might be less effective due to poor absorption. Combining oral Dutasteride with topical Finasteride could potentially enhance results by blocking DHT in both the scalp and serum.

      community Pp405 - lowkey kinda bad results

      in Treatment  16 upvotes 11 months ago
      PP405 increased hair density by 20% in 31% of participants, but results are considered underwhelming. Minoxidil and finasteride are seen as more effective treatments.

      community New article on PP405..........

      in Research/Science  109 upvotes 1 year ago
      Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

      community Tressless users finding the Scroll of Truth

      in Satire  131 upvotes 1 year ago
      The conversation humorously discusses hair loss treatments, focusing on the use of finasteride and dutasteride, with some users debating the effectiveness and cost of different dosages. Some users mention using topical minoxidil and express concerns about side effects and availability of higher doses.

      community 24M oral fin/min 1 year progress

      in Progress Pictures  405 upvotes 1 year ago
      A 24-year-old male shares his one-year progress using oral finasteride (1 mg) and minoxidil (3 mg) for hair growth, reporting positive results without significant side effects. Other users discuss their experiences with these treatments, including concerns about side effects and the importance of consulting a doctor.

      community High Nicotine use and Hair Loss

      in Chat  91 upvotes 1 year ago
      Heavy nicotine use can lead to hair thinning and loss, but quitting can reverse these effects. The user noticed significant hair regrowth after quitting vaping.