The conversation discusses the potential of developing a selective oral SARM to target androgen activity in the scalp and skin, as an alternative to oral Dutasteride and Finasteride, which have systemic side effects. It also mentions Clascoterone and RU58841 as topical treatments for hair loss.
21-year-old female experiencing hair loss and visible scalp seeks advice on PRP effectiveness. Currently taking spironolactone and krimson for high androgens, unsure if PRP can be done with these medications.
Hair transplant recipients are concerned about whether dormant follicles are permanently damaged by incisions, but some believe undamaged follicles could still regrow if a treatment like PP405 is effective. Opinions vary on the impact of transplants on original follicles, with some suggesting treatments like finasteride can help regrow hair.
Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.
The user has seen no regrowth after 1 year and 2 months on finasteride, despite increasing the dose, and is inquiring about the potential of future treatments like verteporfin and gt20029 for hair regrowth.
The conversation discusses hair loss treatments, specifically mentioning Spiro, Min, Fin, and RU. It highlights that Spiro is generally for women and can affect men's hormonal balance.
The user experienced significant hair regrowth after 2.5 years of using Minoxidil 5% and hormone replacement therapy (HRT) with Lupron, despite initial scalp irritation. Finasteride was ineffective for them.
A user is considering using a 0.025% topical finasteride solution with DMSO to enhance absorption but is unsure about its effectiveness and safety. Other users express concerns about DMSO's properties and potential effects on the scalp.
A user shared their hair transplant experience with 5,100 grafts at Hair of Istanbul, costing $4,500, but many commenters suspect the post is promotional for the clinic. The user did not use Minoxidil or Finasteride post-surgery, which some commenters criticized.
A female user's experience with topical and oral finasteride for hair loss, which has been successful as evidenced by the reduction of miniaturized hairs. Replies to the post discussed the recommended dosage for females versus males.
A new company is introducing a topical treatment combining Minoxidil, Finasteride, and Bimatoprost for hair loss. Users are also inquiring about updates on a minoxidil-enhancing shampoo from Applied Biology.
A user shared their positive experience with Laq herbal shampoo and Sevich Batana oil for hair loss due to PCOS and an unbalanced diet. They noticed significant improvement after three weeks of using these products.
A user shared a 2-year progress picture showing improvement in hair loss using only finasteride, with others discussing their own experiences and considering additional treatments like minoxidil or hair transplants. Some users reported hair loss stabilization, while one user experienced regrowth after increasing their finasteride dosage.
Significant hair regrowth was achieved using oral finasteride 1mg, oral minoxidil 5mg daily, ketoconazole shampoo, and dermarolling. It is advised to continue this regimen for 12-18 months before considering any changes.
User shared 6-month progress using topical finasteride, biotin, and occasional dermarolling, reporting no side effects except possible depression. Replies praised the results and shared personal experiences with finasteride.
The user is exploring topical Saw Palmetto as a milder alternative to microdosing topical Finasteride for hair loss, aiming to minimize systemic DHT impact. They plan to experiment with this herbal remedy for a year to assess its effectiveness on their mild androgenetic alopecia without significant side effects.
User noticed beard and sideburn hair loss, and thinning eyebrows, diagnosed with alopecia barbae and male pattern baldness, and prescribed Desonide cream. User seeks feedback on Desonide cream.
Minoxidil helped with temple regrowth, and finasteride improved overall hair appearance and stopped further hair loss. Minoxidil was also applied to eyebrows and eyelids, with noticeable gains, but was stopped on the beard due to bloating.
Progesterone, hydrocortisone butyrate, and estrone base are discussed as treatments for hair loss. Topical progesterone and dutasteride are suggested to potentially reverse androgenic alopecia.
The user has been using finasteride, minoxidil, and needling for 11 months with limited progress and plans to add sulforaphane for 3 months. Another user suggested trying Procyanidin B2 for better results.
This user experienced severe hair loss, but was able to successfully treat it with finasteride over a two year period. Despite experiencing multiple shedding cycles while on the medication, Mission5896 reported that their hair continued to get thicker and stronger. Additionally, they tried both minoxidil orally and topically, but only found success with finasteride.
A user experienced high estrogen levels after 10 months of taking 1mg oral finasteride but is happy with hair regrowth. They are considering switching to topical finasteride and are also taking DIM and Zinc supplements.
Hair cell therapy and follicle cloning are still in experimental stages, with treatments like hair multiplication and regenerative hair therapy being marketed but not yet proven to create unlimited new follicles. There is skepticism about the effectiveness and legitimacy of these treatments, with some considering them scams.
A user is trying fluridil/topilutamide for hair loss and experiencing side effects like pain in the testicles and genital discomfort. They previously had adverse effects with finasteride, dutasteride, and RU58841, and are considering other treatments like topical dutasteride and spironolactone for maintenance before a hair transplant.
Considering a hair transplant abroad for cost savings, the user seeks experiences and advice on choosing clinics, addressing concerns, and ensuring safety. They are interested in insights from those who have undergone or considered the procedure.
A dermatologist prescribed oral minoxidil, finasteride, and spironolactone, suggesting minoxidil and finasteride as the most effective combination, but with potential side effects. Another user recommended minoxidil (both topical and oral) and spironolactone for female hair loss, advising against finasteride.
A user has been taking finasteride 1mg for 10 years without side effects but is concerned about high estradiol levels affecting weight loss. Another user suggests using estradiol blockers under medical supervision to manage the levels.
The positive effects of one year of treatments with topical minoxidil and oral finasteride for hair loss, with encouraging progress pictures as evidence.
ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.