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      community KX-826 Phase 3 Results Are Out

      in Research/Science  113 upvotes 3 months ago
      KX-826 shows promising results for hair growth with fewer side effects, offering an alternative to finasteride and minoxidil. Users discuss combining it with minoxidil, dermarolling, and Nizoral for improved results.

      community Sebum production even on dutasteride, and its relation to MPB.

      in Finasteride/Dutasteride  6 upvotes 6 months ago
      The conversation discusses managing hair loss and scalp issues, with users sharing experiences using treatments like dutasteride, finasteride, ketoconazole, sulfur soap, and topical anti-androgens. Suggestions include trying sulfur soap, scalp massages, spironolactone, and dietary changes to reduce sebum production and dandruff.

      community About 2 months and 2 weeks in! I think we’re going places!! 🤞🏻

      in Is this regrowth?  173 upvotes 1 year ago
      The user is experiencing significant hair regrowth after 2.5 months using 1mg oral finasteride, 2.5mg oral minoxidil, 5% topical minoxidil, biotin, vitamin D3, fish oil, and weekly microneedling with a 1mm roller. They are considering switching to a derma stamp and are pleased with the results, despite some concerns about using both oral and topical minoxidil together.

      community How would you react if PP405 isn't successful in phase 3 trials?

      in Chat  23 upvotes 6 months ago
      People are discussing their reactions if PP405 fails in phase 3 trials, with some expressing skepticism and others holding onto hope for future treatments like GT20029 and Breezula. Many mention continuing with existing treatments like minoxidil and finasteride, while others express disappointment and consider alternative solutions.

      community So was the Grey Market Breezula fake all along?

      in Research/Science  4 upvotes 6 months ago
      Breezula's effectiveness may depend on the vehicle used for its application, with concerns about the grey market version's formulation. Phase 3 results are promising, but skepticism remains about the grey market product's authenticity and effectiveness.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 6 months ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

      community 6 months on oral Fin and Min Results 😁 oh

      in Is this regrowth?  149 upvotes 1 year ago
      A 23-year-old male shares positive results after 6 months of using oral finasteride and minoxidil for hair loss, noting initial shedding but no side effects. He plans to continue the treatment long-term, emphasizing the importance of early intervention.

      community Solvent for topical fin with low absorption

      in Product  2 upvotes 1 year ago
      The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.

      community Sharing my 3 month progress big 4 - Male 29 yo

      in Progress Pictures  108 upvotes 4 years ago
      User shared 3-month progress using big 4 hair loss treatments: finasteride, ketoconazole shampoo, minoxidil, and microneedling. Others congratulated progress and discussed vitamin D and biotin's role in hair regrowth.

      community 26M Baseline blood work done before Finasteride

      in Finasteride/Dutasteride  8 upvotes 4 years ago
      A person considering finasteride for hair loss checked their hormone levels before starting treatment. They are concerned about the potential increase in estradiol and its effects, as well as the impact on their sex hormone-binding globulin (SHBG) and free testosterone levels.

      community 3 months later: topical min/fin + MN is working

      in Update  2 upvotes 2 years ago
      The user is seeing positive results in hair growth using a combination of topical minoxidil, finasteride, microneedling, and keto shampoo. They also use a red light panel for collagen rebuilding and are happy with the progress.

      community 3 month Progress update w/before and afters - 4 in 1 topical solution

      in Progress Pictures  17 upvotes 9 months ago
      A user shared their 3-month progress using a topical solution containing 0.3% finasteride, 7% minoxidil, 2.2% ketoconazole, and 0.2% biotin, reporting improvements in thinning areas. Another user mentioned using oral finasteride, oral minoxidil, dutasteride, and minoxidil foam, discussing costs and side effects.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Progress and results of 3 months of Fin+ Min

      in Progress Pictures  662 upvotes 5 months ago
      A user shared their 3-month progress using topical Minoxidil 5% and oral Finasteride 1mg daily, along with ketoconazole shampoo and derma stamping, reporting significant hair growth without side effects. Some users doubted the results, while others discussed potential side effects of Finasteride and alternative treatments.

      community Is the clinic diagnosis legit to you ?

      in Transplants  1 upvotes 1 year ago
      The clinic diagnosed the user with NW3 and AGA, noting thinning hair despite using finasteride for 3 years, and suggested PRP and Mesotherapy before considering a transplant. The user questions the necessity of these treatments without confirming retrograde alopecia and its treatability.

      community Recommend biotin supplement with saw palmetto

      in Product  1 upvotes 7 months ago
      The conversation is about recommending a biotin supplement that includes saw palmetto and possibly copper for hair loss. The user is seeking suggestions for these specific ingredients.