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community Pelage Pharmaceutical Raises 120 million to continue PP405 Research. Link inside.

in Research/Science 73 upvotes 6 months ago

Pelage Pharmaceutical raised $120 million to continue research on PP405, a promising hair loss treatment that showed a 20% increase in hair density in 31% of men during a Phase 2a trial. The treatment was well-tolerated, with no systemic absorption, and Phase 3 trials are planned for 2026.

community Starting Pyrilutimide 5% Update

in Treatment 1 upvotes 2 years ago

The user started using Pyrilutamide 5% for hair loss and has not experienced side effects after two days. They previously had side effects from Fluridil and topical Minoxidil 5%, and their hair continued thinning with topical Spironolactone.

community Is there any improvement I have been using Multi-Peptide and Biotin Serums

in Is this regrowth? 1 upvotes 1 year ago

The user has been using Multi-Peptide and Biotin serums for hair loss and is considering starting Fin and Minoxidil. They are seeking feedback on any visible improvement between May and June.

community Don't use PP405 from everychem. it is likely fake.

in Research/Science 66 upvotes 10 months ago

PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

community Switching from Finasteride to RU58841?

in General 168 upvotes 7 months ago

The user experienced severe side effects from finasteride, including cognitive and sexual issues, despite its effectiveness for hair growth. They are considering switching to RU58841 and seek insights from others who have made a similar change.

community PROGRESS! 4 months on fin, 6 months on min

in Update 120 upvotes 6 years ago

The user reported hair regrowth after using 1 mg finasteride daily for 4 months, foam minoxidil twice daily for 6 months, and 5000 mcg biotin daily for 4 months. Commenters are impressed with the results and some are considering starting finasteride after seeing the progress.

community 18 months of 1mg fin and 2.5mg oral min daily no luck

in General 39 upvotes 5 months ago

The user has been using 1mg finasteride and 2.5mg oral minoxidil daily for 18 months without success in treating hair loss. They are frustrated with their diffuse androgenetic alopecia and unsure of what to do next.

community Stopping fin after 1.8 Years??!!

in Finasteride/Dutasteride 10 upvotes 4 months ago

The user is considering stopping finasteride after 1.8 years due to concerns about side effects and is exploring alternatives like minoxidil and topical finasteride. They are also considering microneedling and are advised to wait for new treatments like breezula/clascoterone.

community I think we should all keep an eye out for Pelage PP405. February 2025 will be interesting.

in Technology 120 upvotes 1 year ago

Pelage PP405 is a new hair loss treatment in trials, potentially reactivating dormant hair follicles without affecting hormones. Results are expected in February 2025, offering an alternative to minoxidil and finasteride.

community Bloodwork before/after starting Finasteride (5 months)

in Finasteride/Dutasteride 1 upvotes 11 months ago

A user reported a significant increase in testosterone and estradiol levels after taking Finasteride for 5 months, with estradiol levels rising over 2000%. They plan to consult their doctor, suspecting a lab error, as they feel fine with no side effects.

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