Breezula (clascoterone) Phase 3 hair loss trial results are delayed, with no official updates yet. The acne version is approved, but hair loss results are still pending.
The conversation is about identifying ingredients in a scalp serum and their effects on DHT levels. The serum contains various ingredients like Aqua, Biotin, and Oleanolic Acid.
The user wants to try using 0.025% topical finasteride every day by diluting their 0.1% topical finasteride with alfatradiol, and is asking if it's possible to mix them or if there are other options. They heard that alfatradiol might not be suitable for this purpose.
Mixing minoxidil and alfatradiol in one bottle may affect their effectiveness due to potential stability issues. It's recommended to apply them separately for full benefits.
The user's consideration of taking finasteride as a short-term treatment, while awaiting advances in medical technology such as Pyrilutamide and GT20029; other users' experiences with Finasteride, including potential side effects.
Using tretinoin with minoxidil can cause burning and flaky skin due to alcohol in minoxidil and tretinoin's effects. Solutions include using minoxidil foam, starting with low tretinoin doses, moisturizing, and gradually increasing usage.
The conversation discusses using RU58841, Minoxidil, and finasteride for hair loss treatment. It focuses on homebrewing RU58841 while using other treatments.
The conversation is about making topical finasteride using ethanol. The user is advised to use non-denatured or food-grade ethanol, as denatured ethanol may be harmful with prolonged skin exposure.
New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.
User tried topical fin, dut, min, tret, hydrocortisone, microneedling, nizoral, collagen, propidren supplements, and laser helmet for hair loss with slow progress. They ask if topical spironolactone is a safer, effective alternative to RU for suppressing testosterone and treating hair loss in men.
RU58841 is being mixed with Minoxidil solution, but concerns arise about water causing instability. Mixing with water may lead to hydrolysis, potentially reducing effectiveness.
A user is seeking a UK source for a combined minoxidil and RU58841 solution that doesn't contain scalp-irritating ingredients. They specifically want a product without propylene glycol (PG).
Upcoming hair loss treatments for those who can't tolerate DHT blockers, focusing on Minoxidil, microneedling, and ketoconazole. Promising treatments include GT20029, PP405, KX-826, and RU58841, though RU58841 may not be safe.
The conversation is about using tretinoin with a topical finasteride/minoxidil spray for hair loss. The user seeks information on combining tretinoin with their current treatment.
A 26-year-old man has seen hair regrowth after one month of using oral finasteride (1.1mg), minoxidil (3mg), and biotin daily, along with weekly ketoconazole shampoo and plans to add derma stamping. He reports minimal side effects and attributes an increase in libido to starting exercise, not the hair loss treatments.
Combining dutasteride and an aromatase inhibitor may increase testosterone levels significantly, potentially enhancing athletic performance but also posing health risks like elevated blood pressure and worsened cholesterol. The user is experimenting with dutasteride, anastrozole, minoxidil, and ketoconazole shampoo to manage hair loss and estradiol levels, while monitoring side effects and hormone levels.
The user started using topical finasteride three days ago alongside minoxidil and is experiencing testicular pain, which they believe is a nocebo effect. They are anxious about the dosage and seeking advice on whether increasing the application frequency affects the overall dosage.
Hair loss treatments discussed include cosmeRNA, minoxidil, finasteride, RU58841, and pyrilutamide. Users debate effectiveness, side effects, and upcoming treatments, with some expressing skepticism and others optimism.
The user has been using Minoxidil for 6 months and biotin for 2 months without seeing results and is considering starting finasteride due to receding hair at the right temple. Replies suggest starting finasteride and comment on the user's hairline.
GT20026 is discussed as a potential treatment for hair loss that targets androgen receptors without affecting hormone levels, but it may not promote significant regrowth. It is expected to be available by 2028, with other treatments like Breezula and Clascoterone also mentioned.
Topical spironolactone is gaining attention as an alternative hair loss treatment, but it's not as effective as other options like finasteride. Oral spironolactone can cause side effects in men, and there are better topical alternatives like RU, Pyril, and CB.
A user made a 70/30 ethanol/propylene glycol topical finasteride solution but noticed chunks at the bottom. The discussion focuses on this issue with the DIY hair loss treatment.
The user is taking 0.5mg finasteride and 0.5mg Loniten orally daily, using Eucapil twice weekly, and Minoxidil foam once daily for hair loss. They believe Eucapil effectively stops hair loss despite side effects like breast growth.
Capilia Longa and Scandinavian Biolabs are discussed, with skepticism about their effectiveness and value. The conversation suggests avoiding these products due to high cost and perceived lack of results.
The conversation discusses the effectiveness of pyrithione zinc and GT20029 for hair loss. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.
An 18-year-old shares progress in hair regrowth after 1.5 months using a topical treatment with finasteride, ketoconazole, minoxidil, and biotin. They report significant hairline improvement and a decrease in sex drive as a side effect.
The conversation discusses using natural DHT blockers like saw palmetto, beta sitosterol, pumpkin seed oil, pygeum africanum bark, and nettle root as alternatives to finasteride for hair loss, with mixed opinions on their effectiveness. Some users report minimal improvement with natural options and better results with finasteride or dutasteride, despite concerns about potential side effects.
HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.