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GlossaryBlaschko's lines

invisible skin patterns from embryonic cell migration

Blaschko's lines are invisible patterns on human skin that become apparent in certain skin conditions or diseases. These lines represent the pathways of embryonic cell migration and are typically V-shaped on the back, S-shaped on the abdomen, and wavy on the head and extremities. They are not usually visible under normal conditions but can become evident in disorders like lichen planus or epidermal nevi.

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community A new study by Deng and colleagues set out to explore differences between balding and non balding scalps...

in Research/Science 38 upvotes 4 years ago

Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hair follicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hair loss.

community Does anyone have the removed Breezula phase II 12 month baseline comparison results?

in Research/Science 8 upvotes 5 years ago

The conversation discusses the removal of Breezula phase II 12-month results by Cassiopea and the search for the original data. Concerns were raised about potential negative long-term effects on hair growth, such as androgen receptor upregulation.

community The theory that explains everything. The malloclusion theory has been proven.

in Research/Science 27 upvotes 2 years ago

Brian Dye's theory links skeletal malocclusion type II to hair loss, suggesting it's a blood flow issue. Treatments mentioned include minoxidil, finasteride, and anti-inflammatory drugs like benaxoprofen.

community Hair line Mount Rushmore. Bastards lol.

in Chat 851 upvotes 6 months ago

Hairlines and hair loss treatments like finasteride and hair transplants. Celebrities' hairlines are discussed, noting genetics and interventions.

community Mature hairlines in general and defining them

in Chat 13 upvotes 4 years ago

A "mature hairline" is subjective and may not indicate future stability. Finasteride and minoxidil are suggested treatments for hair loss.

community ABS-201 KOL Seminar: Dr. Ralf Paus on Human Ex Vivo Hair Regrowth Data

in Research/Science 15 upvotes 6 months ago

ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.

community If bloodflow, and scalp tightness is cope why does scalp Botox produce results?

in Chat 4 upvotes 3 months ago

Scalp Botox may help hair loss by relaxing muscles and increasing blood flow, potentially benefiting conditions other than androgenetic alopecia. DHT affects hair follicles differently, causing tension and hair loss in some areas but not others.

community Track hairline of Pelage executives

in Research/Science 38 upvotes 8 months ago

Pelage executives' hairlines were discussed, with speculation about them using PP405 for hair regrowth. Concerns were raised about using untested drugs, with some suggesting executives might not risk using them without safety data.

community Are these new follicle?

in Finasteride 58 upvotes 1 year ago

The user is questioning if black points on their scalp are new hair follicles. They are using finasteride and minoxidil for hair growth.

community Thoughts on scalp/hairline tattoos's ?

in Chat 15 upvotes 2 months ago

Scalp tattoos can look good but often appear artificial, especially in sunlight or up close, and require regular maintenance. They may boost confidence if done well, but opinions vary on their effectiveness and natural appearance.

community Dr. Maksim Plikus Putting in the Work!

in Progress Pictures 4 upvotes 3 years ago

The conversation discusses new research on hair growth by Dr. Maksim Plikus, with a call for clinical trials to begin. No specific treatments are mentioned.

community blood flow and scalp tension - put up or shut up

in Chat 31 upvotes 9 months ago

The conversation discusses skepticism about the effectiveness of scalp tension theory and scalp massagers for hair regrowth, contrasting it with treatments like finasteride and minoxidil, which have more user-reported results. Participants question the belief in scalp tension theory, suggesting it may be a marketing tactic, while others argue for a multifactorial approach to hair loss.

community Shiseido filed for this patent in May 2019. Let's get some big brain discussion on this.

4 upvotes 6 years ago

The conversation discusses a patent filed by Shiseido for cloning Dermal Papilla (DP) cells to treat hair loss. The method involves using viral vectors to maintain the cells' growth-inducing properties, differing from Replicel's approach with Dermal Sheath Cup (DSC) cells.

community Hair Multiplication Projects in China - Promising clinical trial results on Mice

in Technology 35 upvotes 1 year ago

A breakthrough in hair follicle cultivation using induced pluripotent stem cells (iPSCs) has been achieved, producing large hair follicles suitable for transplantation. Clinical trials for this hair multiplication technology are planned in partnership with Yinguan Biotechnology.

community Expectations control for SCUBE3

in Research/Science 22 upvotes 2 years ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

community Ronaldo and his Brothers Hairline (10 years difference)

in Chat 498 upvotes 2 years ago

Ronaldo's hairline remains sharp, while his brother's is receding. Opinions vary on whether Ronaldo uses treatments like finasteride or has had hair transplants, with some attributing his hairline to genetics and others to possible medical interventions.

community Dr. Bloxham Final verteporfin update

in Research/Science 59 upvotes 1 year ago

Verteporfin is being explored for its potential to improve hair transplant outcomes by reducing scarring and increasing donor hair follicles. There is skepticism about the results, with some claiming misleading presentation of evidence.

community KX-826 Phase II Results Just Dropped (Male AGA) – Key Takeaways

in Research/Science 14 upvotes 11 months ago

KX-826 Phase II results show that a 0.5% concentration performs better than 1% for treating male pattern baldness. Concerns about receptor upregulation from long-term DHT antagonism were mentioned.

community Breezula phase 3 results said to be released next month

in Product 27 upvotes 1 year ago

Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

community Dr. Bloxham's Verteporfin Trial

in Research/Science 30 upvotes 2 years ago

Dr. Bloxham's trial is testing verteporfin on hair transplant patients to see if it can improve hair regrowth in treated areas. People are discussing the potential for follicle regeneration, expected results timeline, and concerns about side effects like cancer.

community What do you think of these hair transplants?

in Transplants 304 upvotes 7 months ago

Hair transplants in Bangkok are praised for their natural appearance, with a zigzag hairline design being favored over straight lines. The clinic Hairtran and Dr. Patty receive positive feedback, though some users express skepticism about photo filters and the authenticity of results.

community Koshine826 - LX-826? machine translation of the news article

in Product 5 upvotes 1 year ago

KOSHINE826 is a new anti-hair loss and hair growth solution that claims to effectively control oil, reduce hair fall, and promote real hair growth. It targets androgenetic alopecia by inhibiting DHT and has shown promising results in clinical trials.

community Published in Nature: Osteopontin, a protein involved in the growth of hair on moles could be the key to our troubles.

in Research/Science 12 upvotes 2 years ago

Osteopontin, a protein involved in hair growth on moles, may help with hair loss. However, it is also linked to Alzheimer's, cancer, and bone development, so caution is advised.

community Is trichogram a good thing for testing genetic hair loss

in Research/Science 2 upvotes 4 months ago

A dermatologist checked for hereditary hair loss using blood tests and plans to perform a trichogram. The user had slightly low Vitamin D3 levels, and the trichogram may help confirm androgenetic alopecia.

community Clascoterone study going on right now

in Research/Science 355 upvotes 2 years ago

A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hair growth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.

community Pelage Recruiting Now for Phase 2

in Research/Science 11 upvotes 2 years ago

Pelage is recruiting for phase 2 trials, showing promise for treating bald regions. The discussion highlights its potential effectiveness based on its mechanism of action.

community Kintor Pharma Announced Successful Dosing of the First Patient for Acne Vulgaris Phase II Clinical Trial of KX-826

in Research/Science 11 upvotes 4 years ago

Kintor Pharma successfully dosed the first patient in a Phase II trial for KX-826 for acne vulgaris. Users are more interested in results for male pattern baldness (MPB).

community Hair follicle neogenesis

7 upvotes 11 years ago

A user plans to experiment with creating new hair follicles using methods like derma rolling, applying lithium chloride, tannic acid, and various other substances including caffeine, ketoconazole, and raspberry ketones. They also consider using anti-inflammatories, immunosuppressants, and DHT inhibitors to potentially improve results.

community Han Bio Planning Hair Multiplication Trial This Year?

in Technology 6 upvotes 5 years ago

Han Bio plans to start clinical trials for a new hair multiplication technology this year, which could significantly reduce the cost and time of hair transplantation. The technology uses a single hair strand to cultivate enough cells for 30,000 hair strands.

community Dr. Tsuji online lectures today and tomorrow

in Research/Science 4 upvotes 5 years ago

Dr. Tsuji is giving online lectures about hair multiplication trials. Users express hope for a cure, but some are skeptical about its timeline.