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      community How's your progress on kx-826 (pyrilutamide)?

      in Treatment  11 upvotes 1 month ago
      People are discussing their experiences with kx-826 (pyrilutamide) for hair loss, using concentrations of 0.5% and 0.9%. They are sharing personal results and progress with this treatment.

      community 1 year and 2 months on fin and no regrowth

      in Chat  13 upvotes 2 years ago
      The user has seen no regrowth after 1 year and 2 months on finasteride, despite increasing the dose, and is inquiring about the potential of future treatments like verteporfin and gt20029 for hair regrowth.

      community Ru58841 + Minox progress (1 month

      in Progress Pictures  15 upvotes 2 years ago
      A user shared their one-month progress using Minoxidil and RU58841 for hair loss, noting significant shedding after micro-needling and seeking opinions on their regrowth. They stopped micro-needling and added RU58841 to their treatment.

      community Approve PP405 quickly you coward

      in Satire  193 upvotes 11 months ago
      Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

      community Pelage Recruiting Now for Phase 2

      in Research/Science  11 upvotes 2 years ago
      Pelage is recruiting for phase 2 trials, showing promise for treating bald regions. The discussion highlights its potential effectiveness based on its mechanism of action.

      community GT20029 Will Replace Finasteride For Hair Loss

      in Research/Science  50 upvotes 4 weeks ago
      GT20029 shows promise as a topical treatment for hair loss, potentially replacing finasteride for some due to its low systemic exposure and ability to degrade androgen receptors. However, skepticism remains about its long-term efficacy and availability, with some users expressing doubt about new treatments consistently failing to reach the market.

      community Is Pyri worth it at the moment?

      in Chat  26 upvotes 2 years ago
      The conversation is about the effectiveness and safety of a hair loss treatment called Pyri, with users discussing its availability and comparing it to other treatments like RU58841, fluridil, and alfatradiol. Some users are waiting for FDA approval before using Pyri, while others share their positive experiences with RU58841 and suggest additional treatments with minimal side effects.

      community Verteporfin Update with Dr Blake Bloxham

      in Research/Science  27 upvotes 2 years ago
      The conversation discusses Dr. Blake Bloxham's experiment with Verteporfin for hair loss, with one person suggesting more doctors should try it as it seems beneficial. Another comment notes that results at 4-5 months were not very impressive.

      community RCP (redensyl, capixyl, procapil) combination over minoxidil long term?

      in Treatment  5 upvotes 5 years ago
      The conversation discusses using a combination of redensyl, capixyl, and procapil (RCP) for hair loss, with some users also mentioning minoxidil and finasteride. Users shared mixed experiences, with some suggesting "RevivHair Max Hair Stimulating Serum" for better results, while others reported no noticeable effects from using products like The Ordinary Multi-Peptide Serum.

      community 23M Wierd blood test results after 7 months on finasteroid (1mg daily)

      in Finasteride/Dutasteride  5 upvotes 5 months ago
      A user experienced unexpected hormone test results after 7 months on 1mg daily finasteride, noting a decrease in estradiol despite expectations of an increase. Other users suggested that hormone responses can vary and that finasteride might still be effective if DHT levels are within range, while also mentioning factors like circadian rhythm and stress that could impact results.

      community Am I the chosen one? Minoxidil experience.

      in Research/Science  25 upvotes 2 years ago
      A user applied Minoxidil foam to their face to grow a beard and experienced increased hair density and darker hair as unintended benefits, despite initially using it for diffuse thinning on the scalp. Another person suggested that the user's heart rate increase might indicate a high conversion rate of Minoxidil to its active form, similar to taking oral Minoxidil.

      community Pyrilutamide real life results?

      in Research/Science  15 upvotes 3 years ago
      The results of using Pyrilutamide, a hair loss treatment available on the gray market, and other treatments such as Minoxidil, Finasteride and RU58841.

      community How likely do you think it is for PP405 to come out?

      in Research/Science  21 upvotes 8 months ago
      PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  739 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community 10 day solo pyrilutamide update

      in Chat  11 upvotes 3 years ago
      The user started using pyrilutamide for hair loss on January 24, applying 1ml daily without other treatments, and after 10 days noticed reduced hair shedding and improved hair quality, with plans to continue for at least 6 months. They experienced chest pain initially, which could be related to starting methylphenidate or pyrilutamide, but the pain has since subsided.

      community Questions about alfatradiol logistics

      in Treatment  5 upvotes 2 years ago
      The user is seeking help with using Ell-Cranell for hair loss treatment. They are unsure about the correct application method and dosage. They also inquire about combining microneedling with topical alfatradiol and question a study that referred to alfatradiol as a hair growth inhibitor in male mice.

      community Additional supplements / peptides to maximize finasteride benefit

      in Research/Science  3 upvotes 3 weeks ago
      The user is using finasteride, HGH, GHK-CU, BPC-157, KPV, biotin/collagen/keratin vitamins, ketoconazole shampoo, and low-dose naltrexone to address hair loss, avoiding minoxidil due to past shedding experiences. Adenosine is discussed as a potential alternative to minoxidil, though it is noted to be expensive and hard to find.

      community Pyrilutamide release in Europe?

      in Treatment  2 upvotes 3 years ago
      User asks about Pyrilutamide release in Europe, specifically Germany, and considers importing it from China. No specific treatments mentioned.