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CB 03 01 (Breezula) was tried for hair loss but showed no significant improvement, with issues in dissolving and application. Finasteride and dutasteride remain the most effective treatments, while minoxidil is also used; CB's effectiveness is questioned, and topical alternatives like bicalutamide are considered.

Breezula's potential as a hair loss treatment is debated, with some seeing promise despite delays, while others suggest alternatives like Pyrilutamide. Breezula is compared to topical finasteride, with hopes for a better side effect profile.

RU58841's potential side effects, particularly heart palpitations, are debated, with some attributing them to contamination with minoxidil. Users report mixed experiences, with some seeing no side effects and others cautioning about the lack of reliable data on RU58841's safety.

Breezula may be released around 2027 but its effectiveness for advanced thinning is uncertain, and it might be expensive. Users discuss alternatives like low-dose topical finasteride and combining it with Breezula for better results.

The conversation is about alternatives to minoxidil for hair growth, as the original poster experienced chest tightness from using it. They are currently using finasteride and considering options like rosemary oil, pumpkin seed oil, and other topical treatments, but acknowledge that minoxidil and finasteride are the most scientifically supported treatments.

The user experienced anxiety and a rapid heartbeat after restarting finasteride at 0.25-0.3 mg, considering whether to continue or stop. They also use minoxidil but did not have these side effects with minoxidil alone.

, I’m on fin as well. This conversation discussed the user's successful results from 5 weeks of taking an oral minoxidil medication and their experience with hair shedding while using it in combination with finasteride.

The conversation is about hair loss treatments, specifically oral finasteride (1.2mg) and oral minoxidil (3mg), and the user's concern about increased shedding and brittle hair after 7 months of use. It is suggested that shedding is common and may be influenced by stress, and switching to dutasteride might help, but patience is advised as results can take up to a year.

The conversation discusses the removal of Breezula phase II 12-month results by Cassiopea and the search for the original data. Concerns were raised about potential negative long-term effects on hair growth, such as androgen receptor upregulation.

A user shared their positive experience with a clinical trial for a new oral medication, VDPHL01, which is a reformulated version of oral minoxidil taken at a high dose of 17mg daily, showing significant hair regrowth after six months. The user noted that this formulation is believed to be more effective and time-released, with fewer side effects compared to regular oral minoxidil.

The user experienced prolonged hair shedding after restarting oral minoxidil (OM) at 2.5 mg in September 2023, following a break due to hypertrichosis. Despite seeing regrowth, the shedding has not decreased after 11 weeks on the increased dosage.

An 18-year-old experienced chest pain, headaches, and vomiting after taking oral minoxidil for hair loss. They reduced the dosage, felt better, but experienced sharp chest pain again after increasing it, and are advised to stop the medication and see a doctor.

The user is experiencing breast tenderness and lumps after three weeks on 0.5 mg oral finasteride, a common side effect. They also report mild brain fog and fatigue but are less concerned about these symptoms.

User reports 12-week progress with HIMS spray, Minoxidil, micro-needling, and biotin. Notable baby hairs on crown and temples, hoping for further improvement.

New hair loss treatments, including Breezula, VDPHL01, and PP405, are nearing Phase 3 trials, offering hope for effective solutions. Current treatments like finasteride and minoxidil remain effective, but early intervention is crucial.

The conversation is about identifying the vehicle used in the Breezula (clascoterone) trial for hair loss. No specific treatments were mentioned.

User started oral minoxidil 2.5mg in September 2022, experienced initial shedding, then reduced shedding, but now shedding increased again after 8 months. User is a 43-year-old female also on Spironolactone, seeking advice.

A 25-year-old male experienced hair loss after taking breaks from oral dutasteride and minoxidil, leading to concerns about losing progress. He is advised to remain consistent with his current regimen and avoid adding spironolactone.

The user has been using a daily capsule containing 1mg finasteride and 2.5mg minoxidil for 11 months, with noticeable regrowth on the crown but minimal improvement on the hairline. They experienced no significant side effects and plan to continue the treatment long-term.

The user has been using oral finasteride and minoxidil chews for over a year, noticing slowed hair loss in the crown area. They plan to continue this treatment for another nine months before considering switching to Dutasteride if no regrowth occurs.

The conversation discusses the differences between PG/Ethanol and KB solutions for RU58841 application, focusing on potential scalp irritation. KB solution is suggested for those allergic to PG, though both contain ethanol which can dry the scalp.

Oral minoxidil users should monitor heart health with periodic echocardiograms and cardiologist visits due to potential side effects. While some experience serious side effects, they are rare, and the benefits for hair growth often outweigh the risks.

User mixed RU58841 with stemoxydine, experienced no side effects. Mixing RU58841 with fluridil caused chest tightness.

The user experienced hair regrowth using a chewable combination of oral minoxidil and finasteride without side effects, unlike when taken separately. The treatment is from Hims, and the user is satisfied with the progress, especially on the crown.

The user shared progress on hair regrowth after almost 5 months of using oral finasteride and minoxidil, noting improvements in hair thickness, especially around the crown, with some shedding initially. The user reported no significant side effects aside from shedding and sourced the treatment from Hims.

The user experienced significant hair regrowth over five months using Locklabs oral tablets, with no side effects and only a minor shed. They dye their hair black to cover natural blonde, which may affect perceived hair density.

A 30-year-old male experienced rapid hair shedding over 6-7 months due to stress, depression, and nicotine/alcohol use, but has since stopped these habits. He seeks advice on remedies, medications, or diet changes to address hair loss.

A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.

A user shared progress pictures after one year on oral minoxidil and eight months on oral finasteride, noting improved hair density and recession at the corners. The user also mentioned using volumizing shampoo, conditioner, and a homemade sea salt spray, while others debated the necessity and effectiveness of the treatments.

The user has been using finasteride for several years and 2.5mg oral minoxidil for 9 months, noticing stable and slightly thicker hair. They are considering increasing to 5mg oral minoxidil and are concerned about potential shedding or negative effects.